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Protein

Putative pterin-4-alpha-carbinolamine dehydratase

Gene

aq_049

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase (EC:4.2.1.96)
Short name:
PHS
Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name:
PCD
Gene namesi
Ordered Locus Names:aq_049
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000630701 – 99Putative pterin-4-alpha-carbinolamine dehydrataseAdd BLAST99

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_049.

Structurei

3D structure databases

ProteinModelPortaliO66462.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108ZCD. Bacteria.
COG2154. LUCA.
HOGENOMiHOG000007680.
InParanoidiO66462.
KOiK01724.
OMAiHEGGMIR.
OrthoDBiPOG091H05H0.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha. 1 hit.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.

Sequencei

Sequence statusi: Complete.

O66462-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRKLSEEEV KRELENLEGW EFCKDYIQKE FSTKNWKTTI FVVNAIASLA
60 70 80 90
EAQWHHPDLE VSFKKVKVKL TTHEAGGITE RDIKLAKSID ELVKEILKH
Length:99
Mass (Da):11,581
Last modified:August 1, 1998 - v1
Checksum:i6C65B8D7296470F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06420.1.
PIRiC70304.
RefSeqiNP_213022.1. NC_000918.1.
WP_010879960.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06420; AAC06420; aq_049.
GeneIDi1192659.
KEGGiaae:aq_049.
PATRICi20957795. VBIAquAeo85532_0038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06420.1.
PIRiC70304.
RefSeqiNP_213022.1. NC_000918.1.
WP_010879960.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66462.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_049.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06420; AAC06420; aq_049.
GeneIDi1192659.
KEGGiaae:aq_049.
PATRICi20957795. VBIAquAeo85532_0038.

Phylogenomic databases

eggNOGiENOG4108ZCD. Bacteria.
COG2154. LUCA.
HOGENOMiHOG000007680.
InParanoidiO66462.
KOiK01724.
OMAiHEGGMIR.
OrthoDBiPOG091H05H0.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha. 1 hit.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPHS_AQUAE
AccessioniPrimary (citable) accession number: O66462
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.