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Protein

RNA-splicing ligase RtcB

Gene

aq_032

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Mn2+UniRule annotationNote: Binds 2 manganese ions per subunit.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. RNA ligase activity Source: InterPro

GO - Biological processi

  1. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-25-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-splicing ligase RtcBUniRule annotation (EC:6.5.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:aq_032Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798 Componenti: Chromosome

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi224324.aq_032.

Structurei

3D structure databases

ProteinModelPortaliO66450.
SMRiO66450. Positions 6-480.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RtcB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000220065.
InParanoidiO66450.
KOiK14415.
OMAiYDVAHNV.
OrthoDBiEOG6F81M0.

Family and domain databases

InterProiIPR001233. RtcB.
[Graphical view]
PANTHERiPTHR11118. PTHR11118. 1 hit.
PfamiPF01139. RtcB. 1 hit.
[Graphical view]
SUPFAMiSSF103365. SSF103365. 1 hit.

Sequencei

Sequence statusi: Complete.

O66450-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLKEKLIRK GKYIWELPKE TIEGQRVPVI LYLSDALFEL LEEDALRQAA
60 70 80 90 100
NAATLPGVEK AIYVMPDVHV GYGFPVGGVM ATNTETGIIS PGSIGYDINC
110 120 130 140 150
GVRLIATNLK AVDVAPRIKE IMNNMLKNVP AGVGSTSEIK LSKSQMKEVL
160 170 180 190 200
VKGAGWAVEH GFGFPEDLQH IEGFGALPNA DPEKASHEAY ERGSDELGTV
210 220 230 240 250
GSGNHFVEVQ AVEQIYEPEI AEKLGIWEGQ VMVMVHSGSR GFGHQVCTDY
260 270 280 290 300
LRVALKVRDK YKIKLPDPQL ACMPFNSPEG QAYFKAMNAA ANYAFANRQI
310 320 330 340 350
LGFKAANTVR KTLGISWEEF GYRLIYDHAH NIGKVEKHEV DGKKVEVIVH
360 370 380 390 400
RKGATRAFPP YNPEVPPAYR EVGQPVIIPG DMGRASFLLV GQTNSMKMSF
410 420 430 440 450
GTACHGAGRV MSRRQAKKYV KEVGLEKVIG NLVVVARGKG TIMEEIPQAY
460 470 480
KDVTEVVRVI DELGIAKAVA RLKPLGTLKG
Length:480
Mass (Da):52,497
Last modified:July 31, 1998 - v1
Checksum:i63E697BBAAF645C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06415.1.
PIRiG70302.
RefSeqiNP_213010.1. NC_000918.1.
WP_010879948.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06415; AAC06415; aq_032.
GeneIDi1192647.
KEGGiaae:aq_032.
PATRICi20957771. VBIAquAeo85532_0026.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06415.1.
PIRiG70302.
RefSeqiNP_213010.1. NC_000918.1.
WP_010879948.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66450.
SMRiO66450. Positions 6-480.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_032.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06415; AAC06415; aq_032.
GeneIDi1192647.
KEGGiaae:aq_032.
PATRICi20957771. VBIAquAeo85532_0026.

Phylogenomic databases

HOGENOMiHOG000220065.
InParanoidiO66450.
KOiK14415.
OMAiYDVAHNV.
OrthoDBiEOG6F81M0.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-25-MONOMER.

Family and domain databases

InterProiIPR001233. RtcB.
[Graphical view]
PANTHERiPTHR11118. PTHR11118. 1 hit.
PfamiPF01139. RtcB. 1 hit.
[Graphical view]
SUPFAMiSSF103365. SSF103365. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5Imported.

Entry informationi

Entry nameiO66450_AQUAE
AccessioniPrimary (citable) accession number: O66450
Entry historyi
Integrated into UniProtKB/TrEMBL: July 31, 1998
Last sequence update: July 31, 1998
Last modified: March 31, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.