O66426 (YZ38_AQUAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable adenosine monophosphate-protein transferase aq_aa38
EC=2.7.7.n1

Gene names

Ordered Locus Names:

aq_aa38

Encoded on

Plasmid ece1

Organism

Aquifex aeolicus (strain VF5) [Reference proteome] [HAMAP]

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Aquificae › Aquificae › Aquificales › Aquificaceae › Aquifex › Aquifex aeolicus

Protein attributes

Sequence length	320 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins By similarity.
Catalytic activity	ATP + [protein] = diphosphate + [protein]-AMP.
Sequence similarities	Belongs to the fic family. Contains 1 fido domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Plasmid Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro nucleotidyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 320	320	Probable adenosine monophosphate-protein transferase aq_aa38		PRO_0000187004
Regions
	Domain	76 – 206	131	Fido
	Nucleotide binding	100 – 101	2	ATP By similarity
	Nucleotide binding	157 – 159	3	ATP By similarity
Sites
	Binding site	163	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	O66426 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: A395DC9B53D8647A	FASTA	320	37,061
	10 20 30 40 50 60 MTYQNGVEVL LEEFLDYLTK EETICSLEIE KLKVSIDELE KETDEPRVLQ GINYFRTAKE 70 80 90 100 110 120 VYQLSRKAYE TKEEVVSEAL ILWIYENLWK GFNVPKGYRK SDMVIFGAKF SPPPPYVVPN 130 140 150 160 170 180 LIRTIVNWLR NEKTIDVVKK SIIFHTLFEV IHPFPDGNGR VGRILLNAIL VENGLLNVAF 190 200 210 220 230 240 RNREKYISAL REAEEGAIVV VEKLSRGRKI DYSSITETVE YYGNLNVFDE LIRTEMMHSL 250 260 270 280 290 300 KVYSNIKQVF LTPEEAAKLL GLKNKDYVRV LIHRGKLKAV KEEGKWKIPL SEVVKNFEHK 310 320 LKGEEFKLAN NLFKGKLSPS

References

[1]

"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000667 Genomic DNA. Translation: AAC07978.1.
RefSeq	NP_046426.1. NC_001880.1.
3D structure databases
ProteinModelPortal	O66426.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC07978; AAC07978; aq_aa38.
GeneID	1192478.
KEGG	aae:aq_aa38.
PATRIC	20961343. VBIAquAeo85532_1761.
Phylogenomic databases
eggNOG	COG3177.
Enzyme and pathway databases
BioCyc	AAEO224324:GJBH-1609-MONOMER.
Family and domain databases
InterPro	IPR003812. Fido. IPR010093. Xis_DNA-bd. [Graphical view]
Pfam	PF02661. Fic. 1 hit. [Graphical view]
SUPFAM	SSF140931. SSF140931. 1 hit.
TIGRFAMs	TIGR01764. excise. 1 hit.
PROSITE	PS51459. FIDO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YZ38_AQUAE

Accession

Primary (citable) accession number: O66426

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	August 1, 1998
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program