Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60 kDa chaperonin

Gene

groL

Organism
Serratia marcescens
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation, mopA
OrganismiSerratia marcescens
Taxonomic identifieri615 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia

Subcellular locationi

O66206:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000635251 – ›54060 kDa chaperoninAdd BLAST›540

Proteomic databases

PRIDEiO66206.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO66206.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Fragment.

O66206-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVKFGN DARVKMLRGV NVLADAVKVT LGPKGRNVVL DKSFGAPTIT
60 70 80 90 100
KDGVSVAREI ELEDKFENMG AQMVKEVASK ANDAAGDGTT TATVLAQSII
110 120 130 140 150
TEGLKAVAAG MNPMDLKRGI DKAVVAAVEE LKKLSVPCSD SKAIAQVGTI
160 170 180 190 200
SANSDETVGK LIAEAMEKVG KEGVITVEEG TGLQDELDVV EGMQFDRGYL
210 220 230 240 250
SPYFINKPET GSVELESPFI LLADKKISNI REMLPVLEAV AKAGKPLLII
260 270 280 290 300
AEDVEGEALA TLVVNTMRGI VKVAAVKAPG FGDRRKDMLQ DIATLTAGTV
310 320 330 340 350
ISEEIGLELE KATLEDLGQA KRVVINKDTT IIIDGVGDEA TIQGRVAQIR
360 370 380 390 400
QQIEEATSDY DREKLQERVA KLAGGVAVIK VGAATEVEMK EKKARVEDAL
410 420 430 440 450
HATRAAVEEG VVAGGGVALI RVAGKIAALK GDNEDQNVGI KVALRAMEAP
460 470 480 490 500
LRQIVVNAGE EASVIANQVK AGEGSYGYNA YSEEYGDMIA MGILDPTKVT
510 520 530 540
RSALQYAASV AGLMITTECM VTDLPKADAP DLGAXGGMGG
Length:540
Mass (Da):56,672
Last modified:August 1, 1998 - v1
Checksum:iEBE1706F8DB87CBD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei5401

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB008145 Genomic DNA. Translation: BAA25223.1.

Similar proteinsi

Entry informationi

Entry nameiCH60_SERMA
AccessioniPrimary (citable) accession number: O66206
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families