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Protein

Alpha-amylase

Gene

amy

Organism
Streptomyces sp.
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
Name:amyImported
OrganismiStreptomyces sp.Imported
Taxonomic identifieri1931 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500415947825 – 453Alpha-amylaseSequence analysisAdd BLAST429

Structurei

3D structure databases

ProteinModelPortaliO65947.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 366AamyInterPro annotationAdd BLAST336
Domaini375 – 451Aamy_CInterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

O65947-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRTLAGAA RSRALVMTPT TAQASPPGTK DVTAVLFEWK YDSVAKECTS
60 70 80 90 100
HLGPGLPYVQ VSPPAEHIQG SQWWTSYQPV SYKIAGPVGD RTAFRNMVNT
110 120 130 140 150
CHAAGVKVVA DTVINHMSAG SGTGTGGSSY TKYSYPGLYS SYDFDDSTSQ
160 170 180 190 200
VTNYQDRWNV QHCELVGLAD LDTGESYVRG GIARYMNDLL SLGVDGFRID
210 220 230 240 250
AAKHIDAADL ANIKSRLTNP SVYWKQEVIY GAGEAVQPTE YTGNGDVQEF
260 270 280 290 300
PYAYDLKRVF NNENLAYLKN YGEAWGYLNS SVAGVFVDNH DTDANGSTLN
310 320 330 340 350
YRDGANYTLA NVFMLAWPYG APDINSGYEW SDAAAGPPNA TVNACWQDGW
360 370 380 390 400
KCQHKWPEII RMVGFRNATR GQAVTDWWDN GGDAIAFGRG SKGFVAINHE
410 420 430 440 450
SATISRTYQT SLPPGPYCNV QNNTTCSVNG SGQLTATLAA NTALAVYAGK

SSC
Length:453
Mass (Da):49,048
Last modified:August 1, 1998 - v1
Checksum:i297A22A46DB1DCB1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y13332 Genomic DNA. Translation: CAA73775.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y13332 Genomic DNA. Translation: CAA73775.1.

3D structure databases

ProteinModelPortaliO65947.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO65947_STRSQ
AccessioniPrimary (citable) accession number: O65947
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.