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Protein

Putative leucine-rich repeat receptor-like protein kinase At2g19210

Gene

At2g19210

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei603ATPPROSITE-ProRule annotation1
Active sitei699Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi582 – 590ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative leucine-rich repeat receptor-like protein kinase At2g19210 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:At2g19210
ORF Names:F27F23.1
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G19210.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26 – 518ExtracellularSequence analysisAdd BLAST493
Transmembranei519 – 539HelicalSequence analysisAdd BLAST21
Topological domaini540 – 881CytoplasmicSequence analysisAdd BLAST342

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000040133526 – 881Putative leucine-rich repeat receptor-like protein kinase At2g19210Add BLAST856

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi143N-linked (GlcNAc...)Sequence analysis1
Glycosylationi234N-linked (GlcNAc...)Sequence analysis1
Glycosylationi295N-linked (GlcNAc...)Sequence analysis1
Glycosylationi310N-linked (GlcNAc...)Sequence analysis1
Glycosylationi404N-linked (GlcNAc...)Sequence analysis1
Glycosylationi419N-linked (GlcNAc...)Sequence analysis1
Glycosylationi435N-linked (GlcNAc...)Sequence analysis1
Glycosylationi446N-linked (GlcNAc...)Sequence analysis1
Glycosylationi462N-linked (GlcNAc...)Sequence analysis1
Modified residuei734PhosphothreonineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO65924.
PRIDEiO65924.

Expressioni

Gene expression databases

GenevisibleiO65924. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G19210.1.

Structurei

3D structure databases

ProteinModelPortaliO65924.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati438 – 460LRR 1Add BLAST23
Repeati462 – 483LRR 2Add BLAST22
Domaini576 – 850Protein kinasePROSITE-ProRule annotationAdd BLAST275

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 2 LRR (leucine-rich) repeats.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IID2. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116550.
InParanoidiO65924.
OMAiRIWIPLR.
OrthoDBiEOG09360280.
PhylomeDBiO65924.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR024788. Malectin-like_Carb-bd_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF12819. Malectin_like. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O65924-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHYNFLSLI IFACFFAVFV LLVRAQDQSG FVSIDCGIPE DSSYNDETTD
60 70 80 90 100
IKYVSDAAFV ESGTIHSIDP EFQTSSLEKQ FQNVRSFPEG NRNCYDVKPP
110 120 130 140 150
QGKGFKYLIR TRFMYGNYDN LGKAPDFDLY LGFNIWDSVT IDNATTIVTK
160 170 180 190 200
EIIHTLRSDH VHVCLVDKNR GTPFLSALEI RLLKSNTYET PYDSLILFKR
210 220 230 240 250
WDLGGLGALP VRYKDDVFDR IWIPLRFPKY TIFNASLTID SNNNEGFQPA
260 270 280 290 300
RFVMNTATSP EDLSQDIIFS WEPKDPTWKY FVYMHFAEVV ELPSNETREF
310 320 330 340 350
KVLLNEKEIN MSSFSPRYLY TDTLFVQNPV SGPKLEFRLQ QTPRSTLPPI
360 370 380 390 400
INAIETYRVN EFLQSPTDQQ DVDAIMRIKS KYGVKKSWLG DPCAPVKYPW
410 420 430 440 450
KDINCSYVDN ESPRIISVNL SSSGLTGEID AAFSNLTLLH ILDLSNNSLT
460 470 480 490 500
GKIPDFLGNL HNLTELNLEG NKLSGAIPVK LLERSNKKLI LLRIDGNPDL
510 520 530 540 550
CVSASCQISD EKTKKNVYII PLVASVVGVL GLVLAIALFL LYKKRHRRGG
560 570 580 590 600
SGGVRAGPLD TTKRYYKYSE VVKVTNNFER VLGQGGFGKV YHGVLNDDQV
610 620 630 640 650
AVKILSESSA QGYKEFRAEV ELLLRVHHKN LTALIGYCHE GKKMALIYEF
660 670 680 690 700
MANGTLGDYL SGEKSYVLSW EERLQISLDA AQGLEYLHNG CKPPIVQRDV
710 720 730 740 750
KPANILINEK LQAKIADFGL SRSVALDGNN QDTTAVAGTI GYLDPEYHLT
760 770 780 790 800
QKLSEKSDIY SFGVVLLEVV SGQPVIARSR TTAENIHITD RVDLMLSTGD
810 820 830 840 850
IRGIVDPKLG ERFDAGSAWK ITEVAMACAS SSSKNRPTMS HVVAELKESV
860 870 880
SRARAGGGSG ASSVTDPAMT NFDSGMFPQA R
Length:881
Mass (Da):98,433
Last modified:August 1, 1998 - v1
Checksum:iB94105659A923A54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002392 Genomic DNA. Translation: AAM14837.1.
AC003058 Genomic DNA. Translation: AAC16451.1.
CP002685 Genomic DNA. Translation: AEC06857.1.
PIRiT01269.
RefSeqiNP_179511.1. NM_127478.1.
UniGeneiAt.52826.

Genome annotation databases

EnsemblPlantsiAT2G19210.1; AT2G19210.1; AT2G19210.
GeneIDi816438.
GrameneiAT2G19210.1; AT2G19210.1; AT2G19210.
KEGGiath:AT2G19210.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002392 Genomic DNA. Translation: AAM14837.1.
AC003058 Genomic DNA. Translation: AAC16451.1.
CP002685 Genomic DNA. Translation: AEC06857.1.
PIRiT01269.
RefSeqiNP_179511.1. NM_127478.1.
UniGeneiAt.52826.

3D structure databases

ProteinModelPortaliO65924.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G19210.1.

Proteomic databases

PaxDbiO65924.
PRIDEiO65924.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G19210.1; AT2G19210.1; AT2G19210.
GeneIDi816438.
GrameneiAT2G19210.1; AT2G19210.1; AT2G19210.
KEGGiath:AT2G19210.

Organism-specific databases

TAIRiAT2G19210.

Phylogenomic databases

eggNOGiENOG410IID2. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116550.
InParanoidiO65924.
OMAiRIWIPLR.
OrthoDBiEOG09360280.
PhylomeDBiO65924.

Miscellaneous databases

PROiO65924.

Gene expression databases

GenevisibleiO65924. AT.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR024788. Malectin-like_Carb-bd_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF12819. Malectin_like. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY2921_ARATH
AccessioniPrimary (citable) accession number: O65924
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.