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Protein

Putative leucine-rich repeat receptor-like protein kinase At2g19210

Gene

At2g19210

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei603 – 6031ATPPROSITE-ProRule annotation
Active sitei699 – 6991Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi582 – 5909ATPPROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT2G19210-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative leucine-rich repeat receptor-like protein kinase At2g19210 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:At2g19210
ORF Names:F27F23.1
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G19210.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini26 – 518493ExtracellularSequence analysisAdd
BLAST
Transmembranei519 – 53921HelicalSequence analysisAdd
BLAST
Topological domaini540 – 881342CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 881856Putative leucine-rich repeat receptor-like protein kinase At2g19210PRO_0000401335Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi143 – 1431N-linked (GlcNAc...)Sequence analysis
Glycosylationi234 – 2341N-linked (GlcNAc...)Sequence analysis
Glycosylationi295 – 2951N-linked (GlcNAc...)Sequence analysis
Glycosylationi310 – 3101N-linked (GlcNAc...)Sequence analysis
Glycosylationi404 – 4041N-linked (GlcNAc...)Sequence analysis
Glycosylationi419 – 4191N-linked (GlcNAc...)Sequence analysis
Glycosylationi435 – 4351N-linked (GlcNAc...)Sequence analysis
Glycosylationi446 – 4461N-linked (GlcNAc...)Sequence analysis
Glycosylationi462 – 4621N-linked (GlcNAc...)Sequence analysis
Modified residuei734 – 7341PhosphothreonineBy similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO65924.
PRIDEiO65924.

Expressioni

Gene expression databases

GenevisibleiO65924. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G19210.1.

Structurei

3D structure databases

ProteinModelPortaliO65924.
SMRiO65924. Positions 384-497, 549-847.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati438 – 46023LRR 1Add
BLAST
Repeati462 – 48322LRR 2Add
BLAST
Domaini576 – 850275Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 2 LRR (leucine-rich) repeats.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IID2. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116550.
InParanoidiO65924.
OMAiRIWIPLR.
OrthoDBiEOG09360280.
PhylomeDBiO65924.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR024788. Malectin-like_Carb-bd_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF12819. Malectin_like. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O65924-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHYNFLSLI IFACFFAVFV LLVRAQDQSG FVSIDCGIPE DSSYNDETTD
60 70 80 90 100
IKYVSDAAFV ESGTIHSIDP EFQTSSLEKQ FQNVRSFPEG NRNCYDVKPP
110 120 130 140 150
QGKGFKYLIR TRFMYGNYDN LGKAPDFDLY LGFNIWDSVT IDNATTIVTK
160 170 180 190 200
EIIHTLRSDH VHVCLVDKNR GTPFLSALEI RLLKSNTYET PYDSLILFKR
210 220 230 240 250
WDLGGLGALP VRYKDDVFDR IWIPLRFPKY TIFNASLTID SNNNEGFQPA
260 270 280 290 300
RFVMNTATSP EDLSQDIIFS WEPKDPTWKY FVYMHFAEVV ELPSNETREF
310 320 330 340 350
KVLLNEKEIN MSSFSPRYLY TDTLFVQNPV SGPKLEFRLQ QTPRSTLPPI
360 370 380 390 400
INAIETYRVN EFLQSPTDQQ DVDAIMRIKS KYGVKKSWLG DPCAPVKYPW
410 420 430 440 450
KDINCSYVDN ESPRIISVNL SSSGLTGEID AAFSNLTLLH ILDLSNNSLT
460 470 480 490 500
GKIPDFLGNL HNLTELNLEG NKLSGAIPVK LLERSNKKLI LLRIDGNPDL
510 520 530 540 550
CVSASCQISD EKTKKNVYII PLVASVVGVL GLVLAIALFL LYKKRHRRGG
560 570 580 590 600
SGGVRAGPLD TTKRYYKYSE VVKVTNNFER VLGQGGFGKV YHGVLNDDQV
610 620 630 640 650
AVKILSESSA QGYKEFRAEV ELLLRVHHKN LTALIGYCHE GKKMALIYEF
660 670 680 690 700
MANGTLGDYL SGEKSYVLSW EERLQISLDA AQGLEYLHNG CKPPIVQRDV
710 720 730 740 750
KPANILINEK LQAKIADFGL SRSVALDGNN QDTTAVAGTI GYLDPEYHLT
760 770 780 790 800
QKLSEKSDIY SFGVVLLEVV SGQPVIARSR TTAENIHITD RVDLMLSTGD
810 820 830 840 850
IRGIVDPKLG ERFDAGSAWK ITEVAMACAS SSSKNRPTMS HVVAELKESV
860 870 880
SRARAGGGSG ASSVTDPAMT NFDSGMFPQA R
Length:881
Mass (Da):98,433
Last modified:August 1, 1998 - v1
Checksum:iB94105659A923A54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002392 Genomic DNA. Translation: AAM14837.1.
AC003058 Genomic DNA. Translation: AAC16451.1.
CP002685 Genomic DNA. Translation: AEC06857.1.
PIRiT01269.
RefSeqiNP_179511.1. NM_127478.1.
UniGeneiAt.52826.

Genome annotation databases

EnsemblPlantsiAT2G19210.1; AT2G19210.1; AT2G19210.
GeneIDi816438.
GrameneiAT2G19210.1; AT2G19210.1; AT2G19210.
KEGGiath:AT2G19210.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002392 Genomic DNA. Translation: AAM14837.1.
AC003058 Genomic DNA. Translation: AAC16451.1.
CP002685 Genomic DNA. Translation: AEC06857.1.
PIRiT01269.
RefSeqiNP_179511.1. NM_127478.1.
UniGeneiAt.52826.

3D structure databases

ProteinModelPortaliO65924.
SMRiO65924. Positions 384-497, 549-847.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G19210.1.

Proteomic databases

PaxDbiO65924.
PRIDEiO65924.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G19210.1; AT2G19210.1; AT2G19210.
GeneIDi816438.
GrameneiAT2G19210.1; AT2G19210.1; AT2G19210.
KEGGiath:AT2G19210.

Organism-specific databases

TAIRiAT2G19210.

Phylogenomic databases

eggNOGiENOG410IID2. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116550.
InParanoidiO65924.
OMAiRIWIPLR.
OrthoDBiEOG09360280.
PhylomeDBiO65924.

Enzyme and pathway databases

BioCyciARA:AT2G19210-MONOMER.

Miscellaneous databases

PROiO65924.

Gene expression databases

GenevisibleiO65924. AT.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR024788. Malectin-like_Carb-bd_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF12819. Malectin_like. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY2921_ARATH
AccessioniPrimary (citable) accession number: O65924
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.