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Protein

Glucose-6-phosphate 1-dehydrogenase

Gene
N/A
Organism
Nicotiana tabacum (Common tobacco)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate dehydrogenase activity Source: UniProtKB-EC
  2. NADP binding Source: InterPro

GO - Biological processi

  1. glucose metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolismUniRule annotation

Keywords - Ligandi

NADPUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate 1-dehydrogenaseUniRule annotation (EC:1.1.1.49UniRule annotation)
OrganismiNicotiana tabacum (Common tobacco)Imported
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Structurei

3D structure databases

ProteinModelPortaliO65856.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glucose-6-phosphate dehydrogenase family.UniRule annotation

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00966. G6PD.
InterProiIPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23429. PTHR23429. 1 hit.
PfamiPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000110. G6PD. 1 hit.
PRINTSiPR00079. G6PDHDRGNASE.
TIGRFAMsiTIGR00871. zwf. 1 hit.
PROSITEiPS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O65856-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGQLQLNPC SSSSVATTFH NGAHKFCRNF NILPFKAHSL ESSVASTFHN
60 70 80 90 100
GIYSRIQPRK HFEIMSSNGF HLNAVSLLDG SASKSMPEQV PLTELENAET
110 120 130 140 150
TVSITVIGAS GDLAKKKIFT ALFALFYEDC LPENFIVFGY SRTKMSDEEL
160 170 180 190 200
RNMISKTLTC RIDQRENCEA KMDHFLERCF YHSGQYHSED DFAELDYKLK
210 220 230 240 250
AKEGSRVSNR LFYLSIPPNI FVDVVRCASL KASSTSGWTR VIVEKPFGRD
260 270 280 290 300
LESSSELTRC LKKYLTEEQI FRIDHYLGKE LVENLSVLRF SNLVFEPLWS
310 320 330 340 350
RNYIRNVQFI FSEDSGTEGR GGYFDNYGII RDIMQNHLLQ ILALFAMETP
360 370 380 390 400
VSMDAEDIRN EKVKVLRSMR PLQLEDVVLG QYKGHSKGGK LYPAYTDDPT
410 420 430 440 450
VPNGSVTPTF SAAALFINNA RWDGVPFLMK AGKALHTRRA EIRVQFRHVP
460 470 480 490 500
GNLYKRNFGT DLDKATNELV LRLQPDEAIY LKINNKVPGL GMRLDRSDLN
510 520 530 540 550
LLYKAKYRGE IPDAYERLLL DAIEGERRLF IRSDELDAAW ALFTPLLKEL
560 570 580
EEKKIAPELY PYGSRGPVGA HYLAAKHNVR WGDLSGDD
Length:588
Mass (Da):66,801
Last modified:August 1, 1998 - v1
Checksum:i68106BC1E1CF5F62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001772 mRNA. Translation: CAA04994.1.
PIRiT03740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001772 mRNA. Translation: CAA04994.1.
PIRiT03740.

3D structure databases

ProteinModelPortaliO65856.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00966. G6PD.
InterProiIPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23429. PTHR23429. 1 hit.
PfamiPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000110. G6PD. 1 hit.
PRINTSiPR00079. G6PDHDRGNASE.
TIGRFAMsiTIGR00871. zwf. 1 hit.
PROSITEiPS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evidence for functional convergence of redox regulation in G6PDH isoforms of cyanobacteria and higher plants."
    Wendt U.K., Hauschild R., Lange C., Pietersma M., Wenderoth I., von Schaewen A.
    Plant Mol. Biol. 40:487-494(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Young sink leavesImported.

Entry informationi

Entry nameiO65856_TOBAC
AccessioniPrimary (citable) accession number: O65856
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: April 1, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.