Reviewed, UniProtKB/Swiss-Prot O65768 (SODC_CARPA)

Names and origin

Protein names

Recommended name:
    Superoxide dismutase [Cu-Zn]
    EC=1.15.1.1

Gene names

Name:

SODCC

Organism

Carica papaya (Papaya)

Taxonomic identifier

3649 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Caricaceae › Carica

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	antioxidant activity Inferred from electronic annotation. Source: UniProtKB-KW copper ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 152	152	Superoxide dismutase [Cu-Zn]		PRO_0000164136
Sites
	Metal binding	45	1	Copper; catalytic By similarity
	Metal binding	47	1	Copper; catalytic By similarity
	Metal binding	62	1	Copper; catalytic By similarity
	Metal binding	62	1	Zinc; structural By similarity
	Metal binding	70	1	Zinc; structural By similarity
	Metal binding	79	1	Zinc; structural By similarity
	Metal binding	82	1	Zinc; structural By similarity
	Metal binding	119	1	Copper; catalytic By similarity
Amino acid modifications
	Disulfide bond	56 ↔ 145		By similarity

Sequences

	Sequence		Length	Mass (Da)
	O65768-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: E17074E8458B9FA3	FASTA	152	15,213
	10 20 30 40 50 60 MVKAVAVLSS SEGVSGTIFF TQAADGPTTV TGEISGLKPG HHGFHVHALG DTTNGCMSTG 70 80 90 100 110 120 PHFNPAGKEH GAPEDDIRHA GDLGNVNVGD DGKVSFSIID SQIPLTGPNS IVGRAVVVHA 130 140 150 DPDDLGKGGH ELSKTTGNAG GRVACGVIGL QG

References

[1]	"Molecular cloning of a cDNA encoding copper/zinc superoxide dismutase from papaya fruit and overexpression in Escherichia coli." Lin M.T., Kuo T.J., Lin C.T. J. Agric. Food Chem. 46:344-348(1998) [PubMed: 10554243] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Tainong 2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y13610 mRNA. Translation: CAA73929.1.
PIR	T09778.
3D structure databases
HSSP	HSSP built from PDB template 1OZU based on UniProtKB P00441.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.15.1.1. 18730.
Family and domain databases
InterPro	IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn. [Graphical view]
Gene3D	G3DSA:2.60.40.200. SOD_Cu_Zn. 1 hit.
PANTHER	PTHR10003. SOD_Cu_Zn. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
ProDom	PD000469. SOD_CU_ZN. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODC_CARPA

Accession

Primary (citable) accession number: O65768

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
Last sequence update:	August 1, 1998
Last modified:	June 16, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)