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O65735 (ALF_CICAR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Fructose-bisphosphate aldolase, cytoplasmic isozyme

EC=4.1.2.13
Gene names
Name:ALDC
OrganismCicer arietinum (Chickpea) (Garbanzo)
Taxonomic identifier3827 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeCicereaeCicer

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the class I fructose-bisphosphate aldolase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionfructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Fructose-bisphosphate aldolase, cytoplasmic isozyme
PRO_0000216920

Sites

Active site1841Proton acceptor By similarity
Active site2261Schiff-base intermediate with dihydroxyacetone-P
Binding site521Substrate
Binding site1421Substrate
Site3591Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphate

Sequences

Sequence LengthMass (Da)Tools
O65735 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: DD68864B745A5195

FASTA35938,452
        10         20         30         40         50         60 
MSNFKSKYHD ELIANAAYIG TPGKGILAAD ESTGTIGKRL ASINVENVET NRRALRELLF 

        70         80         90        100        110        120 
TAPNVLQYLS GVILFEETLY QSTAAGKPFV DVLNEAGVLP GIKVDKGTVE LAGTDGETTT 

       130        140        150        160        170        180 
QGLDGLGARC AKYYEAGARF AKWRAVLKIG PNEPSLSILS IENAYGLARY AVICQENGLV 

       190        200        210        220        230        240 
PIVELEILVD GSHDIHKCAA ITERVLAATY KALSDHHVLL EGTLLKPNMV TPGSDSPKVA 

       250        260        270        280        290        300 
PEVVAEHTVR ALQRTVPAAV PAVVFLSGGQ SEEEATVNLN AINQVKGKKP WTLSFSFGRA 

       310        320        330        340        350 
LQQSTLKAWS GKEENVKNAQ DALLTRAKAN SEATLGTYKG NSQLGEGASE SLHVKDYKY 

« Hide

References

[1]"cDNA and deduced amino-acid sequence of a cytosolic aldolase from Cicer arietinum L. epicotyls."
Dopico B., Munoz F.J., Labrador E.
Plant Gene Register PGR98-110
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Castellana.
Tissue: Etiolated epicotyl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ005041 mRNA. Translation: CAA06308.1.
RefSeqNP_001265896.1. NM_001278967.1.

3D structure databases

ProteinModelPortalO65735.
SMRO65735. Positions 11-359.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO65735.
ProMEXO65735.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID101501462.
KEGGcam:101501462.

Phylogenomic databases

KOK01623.

Enzyme and pathway databases

UniPathwayUPA00109; UER00183.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR000741. Aldolase_I.
IPR013785. Aldolase_TIM.
[Graphical view]
PANTHERPTHR11627. PTHR11627. 1 hit.
PfamPF00274. Glycolytic. 1 hit.
[Graphical view]
PROSITEPS00158. ALDOLASE_CLASS_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALF_CICAR
AccessionPrimary (citable) accession number: O65735
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: August 1, 1998
Last modified: June 11, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways