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Protein

Syntaxin-41

Gene

SYP41

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Vesicle trafficking protein that functions in the secretory pathway.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-6811438 Intra-Golgi traffic
R-ATH-6811440 Retrograde transport at the Trans-Golgi-Network

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-41
Short name:
AtSYP41
Short name:
AtTLG2a
Gene namesi
Name:SYP41
Ordered Locus Names:At5g26980
ORF Names:F2P16.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G26980
TAIRilocus:2148513 AT5G26980

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 301CytoplasmicSequence analysisAdd BLAST301
Transmembranei302 – 322Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002102581 – 322Syntaxin-41Add BLAST322

Proteomic databases

PaxDbiO65359
PRIDEiO65359

Expressioni

Gene expression databases

ExpressionAtlasiO65359 baseline and differential
GenevisibleiO65359 AT

Interactioni

Subunit structurei

Interacts with VTI12 and SYP61 to form a t-SNARE complex and with VPS45.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
VPS45O490486EBI-1750331,EBI-1750377

GO - Molecular functioni

Protein-protein interaction databases

BioGridi18031, 29 interactors
IntActiO65359, 25 interactors
STRINGi3702.AT5G26980.1

Structurei

3D structure databases

ProteinModelPortaliO65359
SMRiO65359
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini226 – 288t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili116 – 146Sequence analysisAdd BLAST31

Sequence similaritiesi

Belongs to the syntaxin family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0809 Eukaryota
COG5325 LUCA
HOGENOMiHOG000190358
InParanoidiO65359
KOiK08489
OMAiRENQSSC
OrthoDBiEOG09360K11
PhylomeDBiO65359

Family and domain databases

InterProiView protein in InterPro
IPR010989 SNARE
IPR006012 Syntaxin/epimorphin_CS
IPR006011 Syntaxin_N
IPR000727 T_SNARE_dom
PfamiView protein in Pfam
PF05739 SNARE, 1 hit
SMARTiView protein in SMART
SM00503 SynN, 1 hit
SM00397 t_SNARE, 1 hit
SUPFAMiSSF47661 SSF47661, 1 hit
PROSITEiView protein in PROSITE
PS00914 SYNTAXIN, 1 hit
PS50192 T_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

O65359-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATRNRTLLF RKYRNSLRSV RAPLSSSSLT GTRSGGVGPV IEMASTSLLN
60 70 80 90 100
PNRSYAPIST EDPGTSSKGA ITVGLPPAWV DVSEEISVNI QRARTKMAEL
110 120 130 140 150
GKAHAKALMP SFGDGKEDQH NIESLTQEIT FLLKKSEKQL QRLSASGPSE
160 170 180 190 200
DSNVRKNVQR SLATDLQLLS MELRKKQSTY LKRLRQQKED GMDLEMNLSR
210 220 230 240 250
NRYRPEEDDF GDMLNEHQMS KIKKSEEVSV EREKEIQQVV ESVNDLAQIM
260 270 280 290 300
KDLSALVIDQ GTIVDRIDYN IENVATTVED GLKQLQKAER TQRHGGMVKC
310 320
ASVLVILCFI MLLLLILKEI FL
Length:322
Mass (Da):36,134
Last modified:August 1, 1998 - v1
Checksum:iC7314E34BA0DD8E9
GO

Sequence cautioni

The sequence AAB61065 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF067789 mRNA Translation: AAC27707.1
AF007270 Genomic DNA Translation: AAB61065.1 Sequence problems.
CP002688 Genomic DNA Translation: AED93636.1
CP002688 Genomic DNA Translation: AED93637.1
CP002688 Genomic DNA Translation: ANM70302.1
RefSeqiNP_001031950.1, NM_001036873.2
NP_001331924.1, NM_001343989.1
NP_198050.1, NM_122580.4
UniGeneiAt.24148

Genome annotation databases

EnsemblPlantsiAT5G26980.1; AT5G26980.1; AT5G26980
AT5G26980.2; AT5G26980.2; AT5G26980
AT5G26980.3; AT5G26980.3; AT5G26980
GeneIDi832756
GrameneiAT5G26980.1; AT5G26980.1; AT5G26980
AT5G26980.2; AT5G26980.2; AT5G26980
AT5G26980.3; AT5G26980.3; AT5G26980
KEGGiath:AT5G26980

Similar proteinsi

Entry informationi

Entry nameiSYP41_ARATH
AccessioniPrimary (citable) accession number: O65359
Secondary accession number(s): O04639
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 12, 2003
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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