Reviewed, UniProtKB/Swiss-Prot O65198 (SODCP_MEDSA)

Names and origin

Protein names

Recommended name:
    Superoxide dismutase [Cu-Zn], chloroplastic
    EC=1.15.1.1

Gene names

Name:

SODCP

Organism

Medicago sativa (Alfalfa)

Taxonomic identifier

3879 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids I › Fabales › Fabaceae › Papilionoideae › Trifolieae › Medicago

Protein attributes

Sequence length	202 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homotetramer By similarity.
Subcellular location	Plastid › chloroplast.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	antioxidant activity Inferred from electronic annotation. Source: UniProtKB-KW copper ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 48	48	Chloroplast Potential
	Chain	49 – 202	154	Superoxide dismutase [Cu-Zn], chloroplastic		PRO_0000032846
Sites
	Metal binding	94	1	Copper; catalytic By similarity
	Metal binding	96	1	Copper; catalytic By similarity
	Metal binding	111	1	Copper; catalytic By similarity
	Metal binding	111	1	Zinc; structural By similarity
	Metal binding	119	1	Zinc; structural By similarity
	Metal binding	128	1	Zinc; structural By similarity
	Metal binding	131	1	Zinc; structural By similarity
	Metal binding	168	1	Copper; catalytic By similarity
Amino acid modifications
	Disulfide bond	105 ↔ 194		By similarity

Sequences

	Sequence		Length	Mass (Da)
	O65198-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 628FB9CD9AFE2D0F	FASTA	202	20,825
	10 20 30 40 50 60 MASHSLMSPS PLTSHSLLRS SFSGVSVKLS PQFSTLSRSK FQPLSVVAAA KKAVAVLKGN 70 80 90 100 110 120 STVEGVVTLT QENESPTTVN VRITGLTPGL HGFHLHEYGD TTNGCISTGP HFNPNQLTHG 130 140 150 160 170 180 APEDEIRHAG DLGNIIADAN GVAEATIVDN QIPLTGPNSV IGRALVVHEL EDDLGKGGHE 190 200 LSLSTGNAGG RLACGVVGLT PV

References

[1]	"Stress related gene expression in Medicago sativa." Deng M., McKersie B.D. Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Leaf.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF056621 mRNA. Translation: AAC14127.1.
3D structure databases
HSSP	HSSP built from PDB template 1SRD based on UniProtKB P07505.
SMR	O65198. Positions 49-202.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.15.1.1. 815.
Family and domain databases
InterPro	IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn. [Graphical view]
Gene3D	G3DSA:2.60.40.200. SOD_Cu_Zn. 1 hit.
PANTHER	PTHR10003. SOD_Cu_Zn. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
ProDom	PD000469. SOD_CU_ZN. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODCP_MEDSA

Accession

Primary (citable) accession number: O65198

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
Last sequence update:	August 1, 1998
Last modified:	June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)