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Protein

RNA polymerase II transcriptional coactivator KELP

Gene

KELP

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. Binds single-stranded DNA (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase II transcriptional coactivator KELP
Gene namesi
Name:KELP
Ordered Locus Names:At4g10920
ORF Names:F25I24.130, F8M12.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G10920.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 165165RNA polymerase II transcriptional coactivator KELPPRO_0000215948Add
BLAST

Proteomic databases

PaxDbiO65155.
PRIDEiO65155.

PTM databases

iPTMnetiO65155.

Expressioni

Gene expression databases

ExpressionAtlasiO65155. baseline and differential.
GenevisibleiO65155. AT.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
KIWIO651544EBI-2112322,EBI-2112286

Protein-protein interaction databases

BioGridi11989. 1 interaction.
IntActiO65155. 1 interaction.
STRINGi3702.AT4G10920.1.

Structurei

3D structure databases

ProteinModelPortaliO65155.
SMRiO65155. Positions 101-159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2712. Eukaryota.
ENOG410XUB8. LUCA.
HOGENOMiHOG000238208.
InParanoidiO65155.
OMAiQEFRGKS.
PhylomeDBiO65155.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
2.30.31.10. 1 hit.
InterProiIPR014876. DEK_C.
IPR009057. Homeodomain-like.
IPR017415. KELP.
IPR003173. PC4.
IPR009044. ssDNA-bd_transcriptional_reg.
[Graphical view]
PfamiPF08766. DEK_C. 1 hit.
PF02229. PC4. 1 hit.
[Graphical view]
PIRSFiPIRSF038156. RNA_pol_II_KELP. 1 hit.
SUPFAMiSSF54447. SSF54447. 1 hit.

Sequencei

Sequence statusi: Complete.

O65155-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKETKEKIE KTVIEILSES DMKEITEFKV RKLASEKLAI DLSEKSHKAF
60 70 80 90 100
VRSVVEKFLD EERAREYENS QVNKEEEDGD KDCGKGNKEF DDDGDLIICR
110 120 130 140 150
LSDKRRVTIQ EFKGKSLVSI REYYKKDGKE LPTSKGISLT DEQWSTFKKN
160
MPAIENAVKK MESRV
Length:165
Mass (Da):19,177
Last modified:August 1, 1998 - v1
Checksum:i6620F1693D40D3D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF053303 mRNA. Translation: AAC08575.1.
AF080118 Genomic DNA. Translation: AAC33951.1.
AL049525 Genomic DNA. Translation: CAB40060.1.
AL161518 Genomic DNA. Translation: CAB81193.1.
CP002687 Genomic DNA. Translation: AEE82943.1.
CP002687 Genomic DNA. Translation: AEE82944.1.
AY085896 mRNA. Translation: AAM63108.1.
BT005847 mRNA. Translation: AAO64782.1.
PIRiT52114.
RefSeqiNP_001078372.1. NM_001084903.1.
NP_192830.1. NM_117160.3.
UniGeneiAt.21693.

Genome annotation databases

EnsemblPlantsiAT4G10920.1; AT4G10920.1; AT4G10920.
AT4G10920.2; AT4G10920.2; AT4G10920.
GeneIDi826690.
GrameneiAT4G10920.1; AT4G10920.1; AT4G10920.
AT4G10920.2; AT4G10920.2; AT4G10920.
KEGGiath:AT4G10920.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF053303 mRNA. Translation: AAC08575.1.
AF080118 Genomic DNA. Translation: AAC33951.1.
AL049525 Genomic DNA. Translation: CAB40060.1.
AL161518 Genomic DNA. Translation: CAB81193.1.
CP002687 Genomic DNA. Translation: AEE82943.1.
CP002687 Genomic DNA. Translation: AEE82944.1.
AY085896 mRNA. Translation: AAM63108.1.
BT005847 mRNA. Translation: AAO64782.1.
PIRiT52114.
RefSeqiNP_001078372.1. NM_001084903.1.
NP_192830.1. NM_117160.3.
UniGeneiAt.21693.

3D structure databases

ProteinModelPortaliO65155.
SMRiO65155. Positions 101-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi11989. 1 interaction.
IntActiO65155. 1 interaction.
STRINGi3702.AT4G10920.1.

PTM databases

iPTMnetiO65155.

Proteomic databases

PaxDbiO65155.
PRIDEiO65155.

Protocols and materials databases

DNASUi826690.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G10920.1; AT4G10920.1; AT4G10920.
AT4G10920.2; AT4G10920.2; AT4G10920.
GeneIDi826690.
GrameneiAT4G10920.1; AT4G10920.1; AT4G10920.
AT4G10920.2; AT4G10920.2; AT4G10920.
KEGGiath:AT4G10920.

Organism-specific databases

TAIRiAT4G10920.

Phylogenomic databases

eggNOGiKOG2712. Eukaryota.
ENOG410XUB8. LUCA.
HOGENOMiHOG000238208.
InParanoidiO65155.
OMAiQEFRGKS.
PhylomeDBiO65155.

Miscellaneous databases

PROiO65155.

Gene expression databases

ExpressionAtlasiO65155. baseline and differential.
GenevisibleiO65155. AT.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
2.30.31.10. 1 hit.
InterProiIPR014876. DEK_C.
IPR009057. Homeodomain-like.
IPR017415. KELP.
IPR003173. PC4.
IPR009044. ssDNA-bd_transcriptional_reg.
[Graphical view]
PfamiPF08766. DEK_C. 1 hit.
PF02229. PC4. 1 hit.
[Graphical view]
PIRSFiPIRSF038156. RNA_pol_II_KELP. 1 hit.
SUPFAMiSSF54447. SSF54447. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation of putative plant transcriptional coactivators using a modified two-hybrid system incorporating a GFP reporter gene."
    Cormack R.S., Hahlbrock K., Somssich I.E.
    Plant J. 14:685-692(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
  2. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiKELP_ARATH
AccessioniPrimary (citable) accession number: O65155
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: August 1, 1998
Last modified: June 8, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.