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O65100 (FRI3_VIGUN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferritin-3, chloroplastic

EC=1.16.3.1
OrganismVigna unguiculata (Cowpea)
Taxonomic identifier3917 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeVigna

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation By similarity.

Catalytic activity

4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

Subunit structure

Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited By similarity.

Subcellular location

Plastidchloroplast By similarity.

Sequence similarities

Belongs to the ferritin family.

Contains 1 ferritin-like diiron domain.

Ontologies

Keywords
   Biological processIron storage
   Cellular componentChloroplast
Plastid
   DomainTransit peptide
   LigandIron
Metal-binding
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processcellular iron ion homeostasis

Inferred from electronic annotation. Source: UniProtKB-KW

iron ion transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionferric iron binding

Inferred from electronic annotation. Source: InterPro

ferroxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 5454Chloroplast Potential
Chain55 – 256202Ferritin-3, chloroplastic
PRO_0000008871

Regions

Domain88 – 241154Ferritin-like diiron
Region55 – 8733Extension peptide (EP)

Sites

Metal binding1051Iron 1 By similarity
Metal binding1401Iron 1 By similarity
Metal binding1401Iron 2 By similarity
Metal binding1431Iron 1 By similarity
Metal binding1891Iron 2 By similarity
Metal binding2231Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
O65100 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 8B913652C017822B

FASTA25628,444
        10         20         30         40         50         60 
MALSCSKVLT FSLSSVVGGD DAKKKLSLCS SSSLSASVNG GGSRNMRVCA AASNAPAPLT 

        70         80         90        100        110        120 
GVIFEPFQEL KKDYLAVPIA PNVSLSRQNY SDEAEAAINE QINVEYNVSY VYHSLFAYFD 

       130        140        150        160        170        180 
RDNIALKGLA KFFKESSEEE REHAEKLIKY QNIRGGRVVL HPITSPPSEF EHPEKGDALY 

       190        200        210        220        230        240 
AMELALSLEK LTNEKLLYVH SVADRNNDAQ LADFIESEFL NEQVESIKKI AEYVTQLRLV 

       250 
GKGHGVWHFD QRLLHD 

« Hide

References

[1]"Occurrence and expression of members of the ferritin gene family in cowpeas."
Wardrop A.J., Wicks R.E., Entsch B.
Biochem. J. 337:523-530(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. N41.
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF052057 mRNA. Translation: AAC06026.1.
PIRT08123.

3D structure databases

ProteinModelPortalO65100.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1260.10. 1 hit.
InterProIPR001519. Ferritin.
IPR009040. Ferritin-like_diiron.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR014034. Ferritin_CS.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PANTHERPTHR11431. PTHR11431. 1 hit.
PfamPF00210. Ferritin. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
PROSITEPS00540. FERRITIN_1. 1 hit.
PS00204. FERRITIN_2. 1 hit.
PS50905. FERRITIN_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFRI3_VIGUN
AccessionPrimary (citable) accession number: O65100
Entry history
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: August 1, 1998
Last modified: February 19, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families