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O65084 (PSB3_PICMA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proteasome subunit beta type-3

EC=3.4.25.1
Alternative name(s):
20S proteasome alpha subunit C
20S proteasome subunit beta-3
Gene names
Name:PBC1
Synonyms:SB65
OrganismPicea mariana (Black spruce) (Abies mariana)
Taxonomic identifier3335 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaPinidaePinalesPinaceaePicea

Protein attributes

Sequence length204 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Catalytic activity

Cleavage of peptide bonds with very broad specificity.

Subunit structure

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the peptidase T1B family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 204204Proteasome subunit beta type-3
PRO_0000148068

Sequences

Sequence LengthMass (Da)Tools
O65084 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: F6F92CEB4BDC17A6

FASTA20422,908
        10         20         30         40         50         60 
MSIFEYNGSA LVAMVGKNCF AIASDRRLGV QLQTIATDFQ RIFKIHDKLY VGLSGLATDV 

        70         80         90        100        110        120 
QTLYQRFAFR HKLYQLREER NMRPETFASL VSALLYEKRF GPYFCQPVIA GLGEDDKPFI 

       130        140        150        160        170        180 
CTMDSIGAKE LAKDFVVAGT AAESLYGACE SMYKPDMEPE ELFETISQAL LSSIDRDCLS 

       190        200 
GWGGHVYVVS PNQVIERTLK GRMD 

« Hide

References

[1]"Sequence-tagged-site (STS) markers of arbitrary genes: development, characterization and analysis of linkage in black spruce."
Perry D.J., Bousquet J.
Genetics 149:1089-1098(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF051246 mRNA. Translation: AAC32146.1.

3D structure databases

ProteinModelPortalO65084.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.60.20.10. 1 hit.
InterProIPR029055. Ntn_hydrolases_N.
IPR016050. Proteasome_bsu_CS.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
[Graphical view]
PfamPF00227. Proteasome. 1 hit.
[Graphical view]
SUPFAMSSF56235. SSF56235. 1 hit.
PROSITEPS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSB3_PICMA
AccessionPrimary (citable) accession number: O65084
Entry history
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: August 1, 1998
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries