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Protein

Thioredoxin H-type

Gene

SB09

Organism
Picea mariana (Black spruce) (Abies mariana)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The H form is known to activate a number of cytosolic enzymes (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei32Deprotonates C-terminal active site CysBy similarity1
Active sitei38NucleophileBy similarity1
Sitei39Contributes to redox potential valueBy similarity1
Sitei40Contributes to redox potential valueBy similarity1
Active sitei41NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin H-type
Short name:
Trx-H
Gene namesi
Name:SB09
OrganismiPicea mariana (Black spruce) (Abies mariana)
Taxonomic identifieri3335 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaPinidaePinalesPinaceaePicea

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001200581 – 125Thioredoxin H-typeAdd BLAST125

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi38 ↔ 41Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliO65049.
SMRiO65049.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 112ThioredoxinPROSITE-ProRule annotationAdd BLAST111

Sequence similaritiesi

Keywords - Domaini

Redox-active center

Family and domain databases

InterProiView protein in InterPro
IPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR013766. Thioredoxin_domain.
PANTHERiPTHR10438. PTHR10438. 1 hit.
PfamiView protein in Pfam
PF00085. Thioredoxin. 1 hit.
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS51352. THIOREDOXIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O65049-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEGNVFACH STEGWRSKLQ EAIDTKRLVA VDFTATWCGP CRVIGPVFVE
60 70 80 90 100
LSKKFPEIFF LKVDVDELRD VAQEWDVEAM PTFIFIKDGK AVDKVVGAKK
110 120
DDLERKVAAL AAAATTTEAT LPAQA
Length:125
Mass (Da):13,732
Last modified:August 1, 1998 - v1
Checksum:i37E1A22E0B5E229F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051206 mRNA. Translation: AAC32111.1.
PIRiT50866.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiTRXH_PICMA
AccessioniPrimary (citable) accession number: O65049
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: May 10, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families