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Protein

Endoglucanase 12

Gene

At2g44540

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei413PROSITE-ProRule annotation1
Active sitei465PROSITE-ProRule annotation1
Active sitei474PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cell wall biogenesis/degradation, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

BioCyciARA:AT2G44540-MONOMER

Protein family/group databases

CAZyiGH9 Glycoside Hydrolase Family 9

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase 12 (EC:3.2.1.4)
Alternative name(s):
Endo-1,4-beta glucanase 12
Gene namesi
Ordered Locus Names:At2g44540
ORF Names:F4I1.52
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G44540
TAIRilocus:2042376 AT2G44540

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_000024926432 – 491Endoglucanase 12Add BLAST460

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi6N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO64889

PTM databases

iPTMnetiO64889

Expressioni

Gene expression databases

ExpressionAtlasiO64889 baseline and differential
GenevisibleiO64889 AT

Interactioni

Protein-protein interaction databases

IntActiO64889, 1 interactor
STRINGi3702.AT2G44540.1

Structurei

3D structure databases

ProteinModelPortaliO64889
SMRiO64889
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IKVV Eukaryota
ENOG410XPC9 LUCA
HOGENOMiHOG000021033
InParanoidiO64889
OMAiMVNATHP
OrthoDBiEOG093607Q1
PhylomeDBiO64889

Family and domain databases

Gene3Di1.50.10.10, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR001701 Glyco_hydro_9
IPR018221 Glyco_hydro_9_His_AS
PfamiView protein in Pfam
PF00759 Glyco_hydro_9, 1 hit
SUPFAMiSSF48208 SSF48208, 1 hit
PROSITEiView protein in PROSITE
PS00592 GLYCOSYL_HYDROL_F9_1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O64889-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQSKNGSSQ CLWTSICIVV LVMSMARGAV STNYAEALQK SLLYFEAQRS
60 70 80 90 100
GKLPPNQKVT WRGDSALKDG SDAHIDLTGG YYDAGDNMKF GFPLAFTTTM
110 120 130 140 150
LAWSNIEMGS ELRAHHEQGN SLRALKWATD YLIKAHPQPN VLYGQVGEGN
160 170 180 190 200
SDHKCWMRPE DMTTPRTSYR IDAQHPGSDL AGETAAAMAA ASIAFAPFDK
210 220 230 240 250
AYANILIGHA KDLFAFAKAH PGLYQNSITN AGGFYASSGY EDELLWAAAW
260 270 280 290 300
LHRATNDQIY LNYLTQASGT GGPRSVFAWD DKFVGAQVLM AKLALERKVG
310 320 330 340 350
SNGKIAEYKS MAEQFICNCA QKGSNNVKKT PGGLLYFLPW NNLQYTTTAS
360 370 380 390 400
FVLSAYSKYL TKAKASIQCP KGALQASDLL QIARSQVDYI LGSNPQKMSY
410 420 430 440 450
MVGVGTNYPK KPHHRAASIV SIRKDKTPVT CSGGYDKWYN NPAPNPNVLM
460 470 480 490
GALVGGPNEN DVYGDERSNF QQAEPATVTV APFVGVLAAV F
Length:491
Mass (Da):53,421
Last modified:August 1, 1998 - v1
Checksum:iE8C02220EA89635B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003672 Genomic DNA Translation: AAC27456.1
AC004521 Genomic DNA Translation: AAM14965.1
CP002685 Genomic DNA Translation: AEC10436.1
PIRiT02410
RefSeqiNP_181982.1, NM_130018.2
UniGeneiAt.12528

Genome annotation databases

EnsemblPlantsiAT2G44540.1; AT2G44540.1; AT2G44540
GeneIDi819062
GrameneiAT2G44540.1; AT2G44540.1; AT2G44540
KEGGiath:AT2G44540

Similar proteinsi

Entry informationi

Entry nameiGUN12_ARATH
AccessioniPrimary (citable) accession number: O64889
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health