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O64888 (KPRS5_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribose-phosphate pyrophosphokinase 5, chloroplastic
EC=2.7.6.1
Alternative name(s):
Phosphoribosyl pyrophosphate synthase 5
Gene names
Name:PRS5
Ordered Locus Names:At2g44530
ORF Names:F16B22.2
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.

Subcellular location

Plastid › chloroplast Potential.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family.

Sequence caution

The sequence AAC27455.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence AAM14963.1 differs from that shown. Reason: Erroneous gene model prediction.

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: O64888-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3333Chloroplast Potential
Chain34 – 394361Ribose-phosphate pyrophosphokinase 5, chloroplastic
PRO_0000141096

Regions

Region288 – 30316Binding of phosphoribosylpyrophosphate Potential

Sites

Metal binding2021Magnesium Potential
Metal binding2041Magnesium Potential
Metal binding2131Magnesium Potential
Metal binding2171Magnesium Potential

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified March 29, 2005. Version 2.
Checksum: 022EFEF64AF12D60

FASTA39442,625
        10         20         30         40         50         60 
MASIVQPSPT FPALNLRRSS LIRPPSSVRF PLKCNAADPY KFDGGNSAGF HLLTGDTVPA 

        70         80         90        100        110        120 
SFSRTRLEDS IYQNTTRLRI FSGTANPILA QEISCYLGLD LGKIKIKRFA DGEIYVQLQE 

       130        140        150        160        170        180 
SVRGCDVFLV QPTCPPANEN LMELLVMIDA CRRASAKTIT AVIPYFGYAR ADRKTQGRES 

       190        200        210        220        230        240 
IAAKLVANLI TQSGADRVLA CDLHSGQSMG YFDIPVDHVY GQPVILDYLA SKAISSEDLV 

       250        260        270        280        290        300 
VVSPDVGGVA RARAFAKKLS DAPLAIVDKR RHGHNVAEVM NLIGDVKGKV AIMVDDMIDT 

       310        320        330        340        350        360 
AGTISKGAAL LHQEGAREVY ACTTHAVFSP PAISRLSSGL FQEVIITNTI PLSEKNYFPQ 

       370        380        390 
LTVLSVANLL GETIWRVHDD CSGAIEPFST LGID

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC003672 Genomic DNA. Translation: AAC27455.1. Sequence problems.
AC004521 Genomic DNA. Translation: AAM14963.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC10434.1.
AY127024 mRNA. Translation: AAM83248.1.
BT001041 mRNA. Translation: AAN46795.1.
IPIIPI00547336.
PIRT02409.
RefSeqNP_181981.2. NM_130017.4.
UniGeneAt.27497.
At.43497.
At.73198.

3D structure databases

ProteinModelPortalO64888.
SMRO64888. Positions 78-382.
ModBaseSearch...

Protein-protein interaction databases

IntActO64888. 1 interaction.
STRING3702.AT2G44530.1-P.

Proteomic databases

PaxDbO64888.
PRIDEO64888.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G44530.1; AT2G44530.1; AT2G44530.
GeneID819061.
KEGGath:AT2G44530.

Organism-specific databases

GeneFarm4839. 468.
TAIRAt2g44530.

Phylogenomic databases

eggNOGCOG0462.
HOGENOMHOG000210449.
InParanoidO64888.
KOK00948.
OMAAFCTHPV.
PhylomeDBO64888.
ProtClustDBPLN02369.

Gene expression databases

ArrayExpressO64888.
GenevestigatorO64888.
GermOnlineAT2G44530. Arabidopsis thaliana.

Family and domain databases

InterProIPR000842. PRib_PP_synth_CS.
IPR000836. PRibTrfase_dom.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. ribP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKPRS5_ARATH
AccessionPrimary (citable) accession number: O64888
Secondary accession number(s): Q8L7T8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: March 29, 2005
Last modified: May 1, 2013
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents