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Protein

Beta-glucosidase 26, peroxisomal

Gene

BGLU26

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of an inducible preinvasion resistance mechanism that prevents penetration of the nonhost fungal species B.graminis and E.pisi.1 Publication

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331SubstrateBy similarity
Binding sitei137 – 1371SubstrateBy similarity
Binding sitei182 – 1821SubstrateBy similarity
Active sitei183 – 1831Proton donorBy similarity
Binding sitei326 – 3261SubstrateBy similarity
Active sitei398 – 3981NucleophileBy similarity
Binding sitei450 – 4501SubstrateBy similarity

GO - Molecular functioni

  • beta-glucosidase activity Source: UniProtKB-EC
  • thioglucosidase activity Source: TAIR

GO - Biological processi

  • carbohydrate metabolic process Source: InterPro
  • defense response by callose deposition in cell wall Source: TAIR
  • defense response to bacterium Source: TAIR
  • defense response to fungus, incompatible interaction Source: TAIR
  • glucosinolate metabolic process Source: TAIR
  • indole glucosinolate catabolic process Source: TAIR
  • induced systemic resistance Source: TAIR
  • response to bacterium Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Plant defense

Enzyme and pathway databases

BioCyciMetaCyc:AT2G44490-MONOMER.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase 26, peroxisomal (EC:3.2.1.21)
Short name:
AtBGLU26
Alternative name(s):
Protein PENETRATION 2
Gene namesi
Name:BGLU26
Synonyms:PEN2
Ordered Locus Names:At2g44490
ORF Names:F4I1.30
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G44490.

Subcellular locationi

GO - Cellular componenti

  • chloroplast envelope Source: TAIR
  • membrane Source: TAIR
  • peroxisome Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Peroxisome

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi183 – 1831E → D: Susceptibility to the nonhost powdery mildew species B.graminis and E.pisi. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 560560Beta-glucosidase 26, peroxisomalPRO_0000389588Add
BLAST

Proteomic databases

PaxDbiO64883.
PRIDEiO64883.

Expressioni

Gene expression databases

GenevestigatoriO64883.

Interactioni

Protein-protein interaction databases

BioGridi4392. 1 interaction.
STRINGi3702.AT2G44490.1-P.

Structurei

3D structure databases

ProteinModelPortaliO64883.
SMRiO64883. Positions 16-488.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni457 – 4582Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.Curated

Phylogenomic databases

eggNOGiCOG2723.
HOGENOMiHOG000088630.
InParanoidiO64883.
KOiK01188.
OMAiVIGYCTW.
PhylomeDBiO64883.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O64883-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHLQRTFPT EMSKGRASFP KGFLFGTASS SYQYEGAVNE GARGQSVWDH
60 70 80 90 100
FSNRFPHRIS DSSDGNVAVD FYHRYKEDIK RMKDINMDSF RLSIAWPRVL
110 120 130 140 150
PYGKRDRGVS EEGIKFYNDV IDELLANEIT PLVTIFHWDI PQDLEDEYGG
160 170 180 190 200
FLSEQIIDDF RDYASLCFER FGDRVSLWCT MNEPWVYSVA GYDTGRKAPG
210 220 230 240 250
RCSKYVNGAS VAGMSGYEAY IVSHNMLLAH AEAVEVFRKC DHIKNGQIGI
260 270 280 290 300
AHNPLWYEPY DPSDPDDVEG CNRAMDFMLG WHQHPTACGD YPETMKKSVG
310 320 330 340 350
DRLPSFTPEQ SKKLIGSCDY VGINYYSSLF VKSIKHVDPT QPTWRTDQGV
360 370 380 390 400
DWMKTNIDGK QIAKQGGSEW SFTYPTGLRN ILKYVKKTYG NPPILITENG
410 420 430 440 450
YGEVAEQSQS LYMYNPSIDT ERLEYIEGHI HAIHQAIHED GVRVEGYYVW
460 470 480 490 500
SLLDNFEWNS GYGVRYGLYY IDYKDGLRRY PKMSALWLKE FLRFDQEDDS
510 520 530 540 550
STSKKEEKKE SYGKQLLHSV QDSQFVHSIK DSGALPAVLG SLFVVSATVG
560
TSLFFKGANN
Length:560
Mass (Da):63,916
Last modified:August 1, 1998 - v1
Checksum:iBDDE6F7ED328CCBC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004521 Genomic DNA. Translation: AAC16095.1.
CP002685 Genomic DNA. Translation: AEC10428.1.
AY091016 mRNA. Translation: AAM14038.1.
BT000990 mRNA. Translation: AAN41390.1.
PIRiT02404.
RefSeqiNP_181977.1. NM_130012.3.
UniGeneiAt.36752.

Genome annotation databases

EnsemblPlantsiAT2G44490.1; AT2G44490.1; AT2G44490.
GeneIDi819056.
KEGGiath:AT2G44490.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004521 Genomic DNA. Translation: AAC16095.1.
CP002685 Genomic DNA. Translation: AEC10428.1.
AY091016 mRNA. Translation: AAM14038.1.
BT000990 mRNA. Translation: AAN41390.1.
PIRiT02404.
RefSeqiNP_181977.1. NM_130012.3.
UniGeneiAt.36752.

3D structure databases

ProteinModelPortaliO64883.
SMRiO64883. Positions 16-488.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4392. 1 interaction.
STRINGi3702.AT2G44490.1-P.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Proteomic databases

PaxDbiO64883.
PRIDEiO64883.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G44490.1; AT2G44490.1; AT2G44490.
GeneIDi819056.
KEGGiath:AT2G44490.

Organism-specific databases

TAIRiAT2G44490.

Phylogenomic databases

eggNOGiCOG2723.
HOGENOMiHOG000088630.
InParanoidiO64883.
KOiK01188.
OMAiVIGYCTW.
PhylomeDBiO64883.

Enzyme and pathway databases

BioCyciMetaCyc:AT2G44490-MONOMER.

Miscellaneous databases

PROiO64883.

Gene expression databases

GenevestigatoriO64883.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. Cited for: GENE FAMILY, NOMENCLATURE.
  5. Cited for: FUNCTION, SUBCELLULAR LOCATION, MUTAGENESIS OF GLU-183.

Entry informationi

Entry nameiBGL26_ARATH
AccessioniPrimary (citable) accession number: O64883
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: August 1, 1998
Last modified: April 29, 2015
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.