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O64882 (BGL17_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-glucosidase 17

Short name=AtBGLU17
EC=3.2.1.21
Gene names
Name:BGLU17
Ordered Locus Names:At2g44480
ORF Names:F4I1.29
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length517 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: O64882-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: O64882-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-102: Missing.
Note: Derived from EST data. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 517494Beta-glucosidase 17
PRO_0000389580

Regions

Region473 – 4742Substrate binding By similarity

Sites

Active site2041Proton donor By similarity
Active site4171Nucleophile By similarity
Binding site541Substrate By similarity
Binding site1581Substrate By similarity
Binding site2031Substrate By similarity
Binding site3461Substrate By similarity
Binding site4661Substrate By similarity

Amino acid modifications

Glycosylation2291N-linked (GlcNAc...) Potential
Glycosylation3611N-linked (GlcNAc...) Potential
Glycosylation3711N-linked (GlcNAc...) Potential
Glycosylation5101N-linked (GlcNAc...) Potential
Disulfide bond223 ↔ 230 By similarity

Natural variations

Alternative sequence1 – 102102Missing in isoform 2.
VSP_038456

Experimental info

Sequence conflict2591E → V in BAC42451. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 1A9E4DD65EE1A760

FASTA51759,121
        10         20         30         40         50         60 
MAIKSIFIII IISIITSISE LYALDPSFLR LSTSLQRSSF PQDFRFGAAS SAYQSEGAAN 

        70         80         90        100        110        120 
VDGREPSIWD TFTKQYPEKI SDGSNGDVAD EFYYRFKEDV AHMKEIGLDS FRFSISWSRI 

       130        140        150        160        170        180 
LPRGTVAGGV NQAGINFYNH LINELISNGI RPLVTLFHWD TPQALEDEYG GFLNPQIVKD 

       190        200        210        220        230        240 
FVEYVDICFK EFGDRVKEWI TINEPNMFAV LGYNVGNIAP GRCSSYVQNC TVGNSATEPY 

       250        260        270        280        290        300 
LVAHYLILSH AATVQLYREK YQSFHGGTIG MTIQTYWMIP KYNTPACREA AKRALDFFFG 

       310        320        330        340        350        360 
WFADPITYGD YPKTMRELVG NRLPKFTKKQ SKMVRGSFDF FGLNYYTSRY VEDVMFYANT 

       370        380        390        400        410        420 
NLSYTTDSRV NQTTEKNGVP VGEPTSADWL FICPEGFQDV LLYIKSKFQN PVILVTENGM 

       430        440        450        460        470        480 
PSENDKSLSV NIALNDEAKI KYHQLHLTAL LEAVSQGADV RGYYIWSLMD DFEWEFGYKY 

       490        500        510 
RYGLVYVDFQ DGLKRHLKSS ALWYHHFLSN SSSYQMD 

« Hide

Isoform 2 [UniParc].

Checksum: DD5945D9BAF200B7
Show »

FASTA41547,698

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
[5]"Functional genomic analysis of Arabidopsis thaliana glycoside hydrolase family 1."
Xu Z., Escamilla-Trevino L.L., Zeng L., Lalgondar M., Bevan D.R., Winkel B.S.J., Mohamed A., Cheng C.-L., Shih M.-C., Poulton J.E., Esen A.
Plant Mol. Biol. 55:343-367(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC004521 Genomic DNA. Translation: AAC16094.1.
CP002685 Genomic DNA. Translation: AEC10426.1.
CP002685 Genomic DNA. Translation: AEC10427.1.
AK117809 mRNA. Translation: BAC42451.1.
AY074629 mRNA. Translation: AAL69445.1.
PIRT02403.
RefSeqNP_001118525.1. NM_001125053.1. [O64882-2]
NP_181976.1. NM_130011.2. [O64882-1]
UniGeneAt.28778.

3D structure databases

ProteinModelPortalO64882.
SMRO64882. Positions 35-508.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT2G44480.1-P.

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Proteomic databases

PaxDbO64882.
PRIDEO64882.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G44480.1; AT2G44480.1; AT2G44480. [O64882-1]
GeneID819055.
KEGGath:AT2G44480.

Organism-specific databases

TAIRAT2G44480.

Phylogenomic databases

eggNOGCOG2723.
HOGENOMHOG000088630.
InParanoidO64882.
KOK01188.
OMAKEWITIN.
PhylomeDBO64882.

Enzyme and pathway databases

BioCycARA:AT2G44480-MONOMER.
ARA:GQT-532-MONOMER.

Gene expression databases

GenevestigatorO64882.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10353. PTHR10353. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGL17_ARATH
AccessionPrimary (citable) accession number: O64882
Secondary accession number(s): B3H6D8, Q8GY78
Entry history
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names