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Protein

Beta-glucosidase 17

Gene

BGLU17

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei54SubstrateBy similarity1
Binding sitei158SubstrateBy similarity1
Binding sitei203SubstrateBy similarity1
Active sitei204Proton donorBy similarity1
Binding sitei346SubstrateBy similarity1
Active sitei417NucleophileBy similarity1
Binding sitei466SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciARA:AT2G44480-MONOMER.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase 17 (EC:3.2.1.21)
Short name:
AtBGLU17
Gene namesi
Name:BGLU17
Ordered Locus Names:At2g44480
ORF Names:F4I1.29
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G44480.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000038958024 – 517Beta-glucosidase 17Add BLAST494

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi223 ↔ 230By similarity
Glycosylationi229N-linked (GlcNAc...)Sequence analysis1
Glycosylationi361N-linked (GlcNAc...)Sequence analysis1
Glycosylationi371N-linked (GlcNAc...)Sequence analysis1
Glycosylationi510N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiO64882.

Expressioni

Gene expression databases

GenevisibleiO64882. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G44480.1.

Structurei

3D structure databases

ProteinModelPortaliO64882.
SMRiO64882.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni473 – 474Substrate bindingBy similarity2

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG0626. Eukaryota.
COG2723. LUCA.
HOGENOMiHOG000088630.
InParanoidiO64882.
KOiK01188.
OMAiKYKNPPI.
OrthoDBiEOG093606W7.
PhylomeDBiO64882.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR033132. Glyco_hydro_1_N_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: O64882-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAIKSIFIII IISIITSISE LYALDPSFLR LSTSLQRSSF PQDFRFGAAS
60 70 80 90 100
SAYQSEGAAN VDGREPSIWD TFTKQYPEKI SDGSNGDVAD EFYYRFKEDV
110 120 130 140 150
AHMKEIGLDS FRFSISWSRI LPRGTVAGGV NQAGINFYNH LINELISNGI
160 170 180 190 200
RPLVTLFHWD TPQALEDEYG GFLNPQIVKD FVEYVDICFK EFGDRVKEWI
210 220 230 240 250
TINEPNMFAV LGYNVGNIAP GRCSSYVQNC TVGNSATEPY LVAHYLILSH
260 270 280 290 300
AATVQLYREK YQSFHGGTIG MTIQTYWMIP KYNTPACREA AKRALDFFFG
310 320 330 340 350
WFADPITYGD YPKTMRELVG NRLPKFTKKQ SKMVRGSFDF FGLNYYTSRY
360 370 380 390 400
VEDVMFYANT NLSYTTDSRV NQTTEKNGVP VGEPTSADWL FICPEGFQDV
410 420 430 440 450
LLYIKSKFQN PVILVTENGM PSENDKSLSV NIALNDEAKI KYHQLHLTAL
460 470 480 490 500
LEAVSQGADV RGYYIWSLMD DFEWEFGYKY RYGLVYVDFQ DGLKRHLKSS
510
ALWYHHFLSN SSSYQMD
Length:517
Mass (Da):59,121
Last modified:August 1, 1998 - v1
Checksum:i1A9E4DD65EE1A760
GO
Isoform 2 (identifier: O64882-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-102: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:415
Mass (Da):47,698
Checksum:iDD5945D9BAF200B7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti259E → V in BAC42451 (PubMed:11910074).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0384561 – 102Missing in isoform 2. CuratedAdd BLAST102

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004521 Genomic DNA. Translation: AAC16094.1.
CP002685 Genomic DNA. Translation: AEC10426.1.
CP002685 Genomic DNA. Translation: AEC10427.1.
AK117809 mRNA. Translation: BAC42451.1.
AY074629 mRNA. Translation: AAL69445.1.
PIRiT02403.
RefSeqiNP_001118525.1. NM_001125053.1. [O64882-2]
NP_181976.1. NM_130011.3. [O64882-1]
UniGeneiAt.28778.

Genome annotation databases

EnsemblPlantsiAT2G44480.1; AT2G44480.1; AT2G44480. [O64882-1]
GeneIDi819055.
GrameneiAT2G44480.1; AT2G44480.1; AT2G44480.
KEGGiath:AT2G44480.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004521 Genomic DNA. Translation: AAC16094.1.
CP002685 Genomic DNA. Translation: AEC10426.1.
CP002685 Genomic DNA. Translation: AEC10427.1.
AK117809 mRNA. Translation: BAC42451.1.
AY074629 mRNA. Translation: AAL69445.1.
PIRiT02403.
RefSeqiNP_001118525.1. NM_001125053.1. [O64882-2]
NP_181976.1. NM_130011.3. [O64882-1]
UniGeneiAt.28778.

3D structure databases

ProteinModelPortaliO64882.
SMRiO64882.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G44480.1.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Proteomic databases

PaxDbiO64882.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G44480.1; AT2G44480.1; AT2G44480. [O64882-1]
GeneIDi819055.
GrameneiAT2G44480.1; AT2G44480.1; AT2G44480.
KEGGiath:AT2G44480.

Organism-specific databases

TAIRiAT2G44480.

Phylogenomic databases

eggNOGiKOG0626. Eukaryota.
COG2723. LUCA.
HOGENOMiHOG000088630.
InParanoidiO64882.
KOiK01188.
OMAiKYKNPPI.
OrthoDBiEOG093606W7.
PhylomeDBiO64882.

Enzyme and pathway databases

BioCyciARA:AT2G44480-MONOMER.

Miscellaneous databases

PROiO64882.

Gene expression databases

GenevisibleiO64882. AT.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR033132. Glyco_hydro_1_N_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBGL17_ARATH
AccessioniPrimary (citable) accession number: O64882
Secondary accession number(s): B3H6D8, Q8GY78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.