Reviewed, UniProtKB/Swiss-Prot O64792 (PIGP_ARATH)

Names and origin

Protein names

Recommended name:
    Phosphatidylinositol N-acetylglucosaminyltransferase subunit P
    EC=2.4.1.198

Gene names

Ordered Locus Names:	At1g61280
ORF Names:	T1F9.23

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	137 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis By similarity.
Catalytic activity	UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.
Pathway	Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.
Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the PIGP family.

Ontologies

Keywords
Biological process	GPI-anchor biosynthesis
Cellular component	Membrane
Domain	Transmembrane
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	GPI anchor biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphatidylinositol N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 137	137	Phosphatidylinositol N-acetylglucosaminyltransferase subunit P		PRO_0000191786
Regions
	Transmembrane	16 – 36	21	Potential
	Transmembrane	58 – 78	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	O64792-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: ADEC3D4906CDF124	FASTA	137	15,611
	10 20 30 40 50 60 MLSLNQEVHG PKTSEVYGFV GSISIVVATV IFLIWGYVPD KFLESIGIYY YPSKYWAMAM 70 80 90 100 110 120 PMYSMVTLLV ALVFYIGLNF MSTSKPTSLN TLFDDYSRED VNFLPLMKNG EDRPIDPISD 130 IDITRINDLM FDSHLAK

References

[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Arabidopsis ORF clones." Bautista-Mercan V.R., Kim C.J., Chen H., Quan R., De Los Reyes C., Ecker J.R. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC004255 Genomic DNA. Translation: AAC13913.1. BT030658 mRNA. Translation: ABR46238.1.
IPI	IPI00540294.
RefSeq	NP_176323.1.
UniGene	At.52300
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O64792.
Genome annotation databases
GeneID	842422.
GenomeReviews	Gene locus AT1G61280 in contig CT485782_GR.
KEGG	ath:AT1G61280.
NMPDR	fig|3702.1.peg.5519.
Organism-specific databases
TAIR	At1g61280.
Phylogenomic databases
OMA	SLGITYY.
Enzyme and pathway databases
BRENDA	2.4.1.198. 302.
Gene expression databases
ArrayExpress	O64792.
Genevestigator	O64792.
GermOnline	AT1G61280. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR013717. PIG-P. IPR016542. PIG-P_GPI19. [Graphical view]
Pfam	PF08510. PIG-P. 1 hit. [Graphical view]
PIRSF	PIRSF008765. PIG-P_GPI19. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PIGP_ARATH

Accession

Primary (citable) accession number: O64792
Secondary accession number(s): A6QRD5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	August 1, 1998
Last modified:	November 3, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)