O64791 (SY124_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Syntaxin-124
Short name=AtSYP124

Gene names

Name:	SYP124
Ordered Locus Names:	At1g61290
ORF Names:	T1F9.22

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Vesicle trafficking protein that functions in the secretory pathway By similarity.
Subunit structure	Part of the t-SNARE complex By similarity.
Subcellular location	Membrane; Single-pass type IV membrane protein By similarity.
Sequence similarities	Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain.

Ontologies

Keywords
Biological process	Protein transport Transport
Cellular component	Membrane
Domain	Coiled coil Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	intracellular protein transport Inferred from electronic annotation. Source: InterPro pollen tube growth Inferred from direct assay PubMed 20718953. Source: TAIR vesicle-mediated transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from direct assay PubMed 20718953. Source: TAIR transport vesicle Inferred from direct assay PubMed 20718953. Source: TAIR
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Syntaxin-124		PRO_0000210249
Regions
	Topological domain	1 – 279	279	Cytoplasmic Potential
	Transmembrane	280 – 300	21	Helical; Anchor for type IV membrane protein; Potential
	Topological domain	301 – 303	3	Vesicular Potential
	Domain	203 – 265	63	t-SNARE coiled-coil homology
	Coiled coil	31 – 112	82	Potential

Sequences

	Sequence		Length	Mass (Da)
	O64791 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: B02A2592CA145210	FASTA	303	34,468
	10 20 30 40 50 60 MNDLFSSSFK KYTDLKQQAQ MDDIESGKET MNLDKFFEDV ENVKDNMKGV ETLYKSLQDS 70 80 90 100 110 120 NEECKTVHNA KKVKELRAKM DGDVAQVLKR VKMIKQKLEA LEKANANSRN VSGCGPGSST 130 140 150 160 170 180 DRTRTSVVSG LGKKLKDLMD SFQGLRARMN AEYKETVERR YFTITGEQAD EQTIENLISS 190 200 210 220 230 240 GESENFLQKA IQEQGRGQIL DTISEIQERH DAVKEIEKNL IELHQVFLDM AALVESQGQQ 250 260 270 280 290 300 LNDIESHVSK ASSFVRRGTD QLQDAREYQK SSRKWTCYAI LLFIVVFALL LIPALPHIML MLK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations." Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P. Plant Biotechnol. J. 4:317-324(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC004255 Genomic DNA. Translation: AAC13912.1. CP002684 Genomic DNA. Translation: AEE33817.1. DQ446382 mRNA. Translation: ABE65730.1.
IPI	IPI00544699.
PIR	G96638.
RefSeq	NP_176324.1. NM_104810.2.
UniGene	At.50658.
3D structure databases
ProteinModelPortal	O64791.
SMR	O64791. Positions 33-286.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT1G61290.1-P.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G61290.1; AT1G61290.1; AT1G61290.
GeneID	842423.
KEGG	ath:AT1G61290.
Organism-specific databases
GeneFarm	2182. 383.
TAIR	At1g61290.
Phylogenomic databases
eggNOG	COG5074.
InParanoid	O64791.
KO	K08486.
OMA	DIESHVS.
PhylomeDB	O64791.
ProtClustDB	CLSN2681842.
Gene expression databases
ArrayExpress	O64791.
Genevestigator	O64791.
Family and domain databases
InterPro	IPR006012. Syntaxin/epimorphin_CS. IPR006011. Syntaxin_N. IPR010989. t-SNARE. IPR000727. T_SNARE_dom. [Graphical view]
Pfam	PF05739. SNARE. 1 hit. PF00804. Syntaxin. 1 hit. [Graphical view]
SMART	SM00503. SynN. 1 hit. SM00397. t_SNARE. 1 hit. [Graphical view]
SUPFAM	SSF47661. t-snare. 1 hit.
PROSITE	PS00914. SYNTAXIN. 1 hit. PS50192. T_SNARE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SY124_ARATH

Accession

Primary (citable) accession number: O64791
Secondary accession number(s): Q1PFI1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	August 1, 1998
Last modified:	May 1, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program