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Protein

Thioredoxin O1, mitochondrial

Gene

At2g35010

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Thiol-disulfide oxidoreductase that may participate in various redox reactions. Possesses insulin disulfide bonds reducing activity. Reduced by thioredoxin reductases NTRA and NTRB.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei118NucleophileBy similarity1
Sitei119Contributes to redox potential valueBy similarity1
Sitei120Contributes to redox potential valueBy similarity1
Active sitei121NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin O1, mitochondrial
Short name:
AtTrxo1
Gene namesi
Ordered Locus Names:At2g35010
ORF Names:F19I3.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G35010
TAIRilocus:2044772 AT2G35010

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 42MitochondrionSequence analysisAdd BLAST42
ChainiPRO_000039453743 – 194Thioredoxin O1, mitochondrialAdd BLAST152

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei75PhosphoserineBy similarity1
Disulfide bondi118 ↔ 121Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Phosphoprotein

Proteomic databases

PaxDbiO64764
PRIDEiO64764

PTM databases

SwissPalmiO64764

Expressioni

Gene expression databases

ExpressionAtlasiO64764 baseline and differential
GenevisibleiO64764 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G35010.1

Structurei

3D structure databases

ProteinModelPortaliO64764
SMRiO64764
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini89 – 194ThioredoxinPROSITE-ProRule annotationAdd BLAST106

Sequence similaritiesi

Keywords - Domaini

Redox-active center, Transit peptide

Phylogenomic databases

eggNOGiKOG0907 Eukaryota
COG0526 LUCA
HOGENOMiHOG000292977
InParanoidiO64764
KOiK03671
OMAiPTFHFYY
OrthoDBiEOG09360UVJ
PhylomeDBiO64764

Family and domain databases

InterProiView protein in InterPro
IPR005746 Thioredoxin
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain
PANTHERiPTHR10438 PTHR10438, 1 hit
PfamiView protein in Pfam
PF00085 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS51352 THIOREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O64764-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGNWSIVRK VLHRQFSTLR SSTPSSRLST SIRPLVLAPN SISSLIARNS
60 70 80 90 100
LFTASNIGPS IDFNFSNTSL PHRRSLCSEA GGENGVVLVK SEEEFINAMS
110 120 130 140 150
KAQDGSLPSV FYFTAAWCGP CRFISPVIVE LSKQYPDVTT YKVDIDEGGI
160 170 180 190
SNTISKLNIT AVPTLHFFKG GSKKGEVVGA DVTKLKNLME QLYK
Length:194
Mass (Da):21,191
Last modified:August 1, 1998 - v1
Checksum:i1DA980E60614606D
GO

Sequence cautioni

The sequence BAC43652 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti110V → A in BAC43652 (PubMed:11910074).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004238 Genomic DNA Translation: AAC12840.1
CP002685 Genomic DNA Translation: AEC09048.1
CP002685 Genomic DNA Translation: AEC09049.1
BT025773 mRNA Translation: ABF83663.1
AK119076 mRNA Translation: BAC43652.1 Different initiation.
PIRiT00482
RefSeqiNP_001078006.1, NM_001084537.1
NP_181046.1, NM_129053.6
UniGeneiAt.37724

Genome annotation databases

EnsemblPlantsiAT2G35010.1; AT2G35010.1; AT2G35010
AT2G35010.2; AT2G35010.2; AT2G35010
GeneIDi818065
GrameneiAT2G35010.1; AT2G35010.1; AT2G35010
AT2G35010.2; AT2G35010.2; AT2G35010
KEGGiath:AT2G35010

Similar proteinsi

Entry informationi

Entry nameiTRXO1_ARATH
AccessioniPrimary (citable) accession number: O64764
Secondary accession number(s): Q8GW51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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