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Protein

Protein transport protein SEC13 homolog B

Gene

SEC13B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for protein transport from the endoplasmic reticulum to the Golgi apparatus.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, mRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

ReactomeiR-ATH-204005 COPII (Coat Protein 2) Mediated Vesicle Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein SEC13 homolog BCurated
Alternative name(s):
SEC13-like protein BCurated
Gene namesi
Name:SEC13B1 Publication
Synonyms:SEC131 Publication
Ordered Locus Names:At2g30050Imported
ORF Names:T27E13.21Curated
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G30050
TAIRilocus:2045648 AT2G30050

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Nuclear pore complex, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004305391 – 302Protein transport protein SEC13 homolog BAdd BLAST302

Proteomic databases

PaxDbiO64740
ProMEXiO64740

Expressioni

Gene expression databases

ExpressionAtlasiO64740 baseline and differential
GenevisibleiO64740 AT

Interactioni

Subunit structurei

Part of the nuclear pore complex (NPC). The NPC has an eight-fold symmetrical structure comprising a central transport channel and two rings, the cytoplasmic and nuclear rings, to which eight filaments are attached. The cytoplasmic filaments have loose ends, while the nuclear filaments are joined in a distal ring, forming a nuclear basket. NPCs are highly dynamic in configuration and composition, and can be devided in 3 subcomplexes, the NUP62 subcomplex, the NUP107-160 subcomplex and the NUP93 subcomplex, containing approximately 30 different nucleoporin proteins. Interacts with MAG5, SEC31A and SEC31B.1 Publication1 Publication

Protein-protein interaction databases

BioGridi2905, 9 interactors
IntActiO64740, 4 interactors
STRINGi3702.AT2G30050.1

Structurei

3D structure databases

ProteinModelPortaliO64740
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati9 – 48WD 1Sequence analysisAdd BLAST40
Repeati54 – 95WD 2Sequence analysisAdd BLAST42
Repeati101 – 142WD 3Sequence analysisAdd BLAST42
Repeati148 – 201WD 4Sequence analysisAdd BLAST54
Repeati208 – 251WD 5Sequence analysisAdd BLAST44
Repeati257 – 296WD 6Sequence analysisAdd BLAST40

Sequence similaritiesi

Belongs to the WD repeat SEC13 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG1332 Eukaryota
ENOG410XPFM LUCA
HOGENOMiHOG000216895
InParanoidiO64740
KOiK14004
OMAiREDNDRW
OrthoDBiEOG09360GCO
PhylomeDBiO64740

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR037596 Sec13
IPR037363 Sec13/Seh1_fam
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR11024 PTHR11024, 1 hit
PTHR11024:SF2 PTHR11024:SF2, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O64740-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGQKIETGH EDIVHDVQMD YYGKRIATAS SDCTIKITGV SNNGGSQQLA
60 70 80 90 100
TLTGHRGPVW EVAWAHPKYG SILASCSYDG QVILWKEGNQ NQWTQDHVFT
110 120 130 140 150
DHKSSVNSIA WAPHDIGLSL ACGSSDGNIS VFTARADGGW DTSRIDQAHP
160 170 180 190 200
VGVTSVSWAP ATAPGALVSS GLLDPVYKLA SGGCDNTVKV WKLANGSWKM
210 220 230 240 250
DCFPALQKHT DWVRDVAWAP NLGLPKSTIA SGSQDGKVII WTVGKEGEQW
260 270 280 290 300
EGKVLKDFMT PVWRVSWSLT GNLLAVSDGN NNVTVWKEAV DGEWEQVTAV

EP
Length:302
Mass (Da):32,642
Last modified:August 1, 1998 - v1
Checksum:iF9D1C36D4F98C8EF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti267W → S in AAM65095 (Ref. 4) 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004165 Genomic DNA Translation: AAC16967.1
AC004680 Genomic DNA Translation: AAM14986.1
CP002685 Genomic DNA Translation: AEC08339.1
AF412112 mRNA Translation: AAL06565.1
AY124848 mRNA Translation: AAM70557.1
AY087553 mRNA Translation: AAM65095.1
PIRiT00593 T02480
RefSeqiNP_180566.1, NM_128560.3
UniGeneiAt.25577
At.74333

Genome annotation databases

EnsemblPlantsiAT2G30050.1; AT2G30050.1; AT2G30050
GeneIDi817556
GrameneiAT2G30050.1; AT2G30050.1; AT2G30050
KEGGiath:AT2G30050

Similar proteinsi

Entry informationi

Entry nameiSC13B_ARATH
AccessioniPrimary (citable) accession number: O64740
Secondary accession number(s): Q8LAX1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 29, 2014
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health