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Protein

Protein transport protein SEC13 homolog B

Gene

SEC13B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Required for protein transport from the endoplasmic reticulum to the Golgi apparatus.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ER-Golgi transport, mRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

ReactomeiR-ATH-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein SEC13 homolog BCurated
Alternative name(s):
SEC13-like protein BCurated
Gene namesi
Name:SEC13B1 Publication
Synonyms:SEC131 Publication
Ordered Locus Names:At2g30050Imported
ORF Names:T27E13.21Curated
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G30050.

Subcellular locationi

GO - Cellular componenti

  • endoplasmic reticulum Source: UniProtKB-SubCell
  • Golgi apparatus Source: UniProtKB-SubCell
  • nuclear envelope Source: TAIR
  • nuclear pore Source: TAIR
  • nucleolus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Nuclear pore complex, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302Protein transport protein SEC13 homolog BPRO_0000430539Add
BLAST

Proteomic databases

PaxDbiO64740.
PRIDEiO64740.
ProMEXiO64740.

Expressioni

Gene expression databases

GenevisibleiO64740. AT.

Interactioni

Subunit structurei

Part of the nuclear pore complex (NPC). The NPC has an eight-fold symmetrical structure comprising a central transport channel and two rings, the cytoplasmic and nuclear rings, to which eight filaments are attached. The cytoplasmic filaments have loose ends, while the nuclear filaments are joined in a distal ring, forming a nuclear basket. NPCs are highly dynamic in configuration and composition, and can be devided in 3 subcomplexes, the NUP62 subcomplex, the NUP107-160 subcomplex and the NUP93 subcomplex, containing approximately 30 different nucleoporin proteins. Interacts with MAG5, SEC31A and SEC31B.1 Publication1 Publication

Protein-protein interaction databases

BioGridi2905. 9 interactions.
IntActiO64740. 4 interactions.
STRINGi3702.AT2G30050.1.

Structurei

3D structure databases

ProteinModelPortaliO64740.
SMRiO64740. Positions 12-294.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati9 – 4840WD 1Sequence analysisAdd
BLAST
Repeati54 – 9542WD 2Sequence analysisAdd
BLAST
Repeati101 – 14242WD 3Sequence analysisAdd
BLAST
Repeati148 – 20154WD 4Sequence analysisAdd
BLAST
Repeati208 – 25144WD 5Sequence analysisAdd
BLAST
Repeati257 – 29640WD 6Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the WD repeat SEC13 family.Curated
Contains 6 WD repeats.Sequence analysis

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG1332. Eukaryota.
ENOG410XPFM. LUCA.
HOGENOMiHOG000216895.
InParanoidiO64740.
KOiK14004.
OMAiREDNDRW.
OrthoDBiEOG09360GCO.
PhylomeDBiO64740.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 5 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O64740-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGQKIETGH EDIVHDVQMD YYGKRIATAS SDCTIKITGV SNNGGSQQLA
60 70 80 90 100
TLTGHRGPVW EVAWAHPKYG SILASCSYDG QVILWKEGNQ NQWTQDHVFT
110 120 130 140 150
DHKSSVNSIA WAPHDIGLSL ACGSSDGNIS VFTARADGGW DTSRIDQAHP
160 170 180 190 200
VGVTSVSWAP ATAPGALVSS GLLDPVYKLA SGGCDNTVKV WKLANGSWKM
210 220 230 240 250
DCFPALQKHT DWVRDVAWAP NLGLPKSTIA SGSQDGKVII WTVGKEGEQW
260 270 280 290 300
EGKVLKDFMT PVWRVSWSLT GNLLAVSDGN NNVTVWKEAV DGEWEQVTAV

EP
Length:302
Mass (Da):32,642
Last modified:August 1, 1998 - v1
Checksum:iF9D1C36D4F98C8EF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti267 – 2671W → S in AAM65095 (Ref. 4)

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004165 Genomic DNA. Translation: AAC16967.1.
AC004680 Genomic DNA. Translation: AAM14986.1.
CP002685 Genomic DNA. Translation: AEC08339.1.
AF412112 mRNA. Translation: AAL06565.1.
AY124848 mRNA. Translation: AAM70557.1.
AY087553 mRNA. Translation: AAM65095.1.
PIRiT00593. T02480.
RefSeqiNP_180566.1. NM_128560.2.
UniGeneiAt.25577.
At.74333.

Genome annotation databases

EnsemblPlantsiAT2G30050.1; AT2G30050.1; AT2G30050.
GeneIDi817556.
GrameneiAT2G30050.1; AT2G30050.1; AT2G30050.
KEGGiath:AT2G30050.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004165 Genomic DNA. Translation: AAC16967.1.
AC004680 Genomic DNA. Translation: AAM14986.1.
CP002685 Genomic DNA. Translation: AEC08339.1.
AF412112 mRNA. Translation: AAL06565.1.
AY124848 mRNA. Translation: AAM70557.1.
AY087553 mRNA. Translation: AAM65095.1.
PIRiT00593. T02480.
RefSeqiNP_180566.1. NM_128560.2.
UniGeneiAt.25577.
At.74333.

3D structure databases

ProteinModelPortaliO64740.
SMRiO64740. Positions 12-294.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2905. 9 interactions.
IntActiO64740. 4 interactions.
STRINGi3702.AT2G30050.1.

Proteomic databases

PaxDbiO64740.
PRIDEiO64740.
ProMEXiO64740.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G30050.1; AT2G30050.1; AT2G30050.
GeneIDi817556.
GrameneiAT2G30050.1; AT2G30050.1; AT2G30050.
KEGGiath:AT2G30050.

Organism-specific databases

TAIRiAT2G30050.

Phylogenomic databases

eggNOGiKOG1332. Eukaryota.
ENOG410XPFM. LUCA.
HOGENOMiHOG000216895.
InParanoidiO64740.
KOiK14004.
OMAiREDNDRW.
OrthoDBiEOG09360GCO.
PhylomeDBiO64740.

Enzyme and pathway databases

ReactomeiR-ATH-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Miscellaneous databases

PROiO64740.

Gene expression databases

GenevisibleiO64740. AT.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 5 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSC13B_ARATH
AccessioniPrimary (citable) accession number: O64740
Secondary accession number(s): Q8LAX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 29, 2014
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.