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Protein

Probable protein phosphatase 2C 26

Gene

At2g30170

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi82Manganese 1By similarity1
Metal bindingi82Manganese 2By similarity1
Metal bindingi83Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi213Manganese 2By similarity1
Metal bindingi286Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • cellular response to light stimulus Source: TAIR
  • peptidyl-threonine dephosphorylation Source: TAIR
  • thylakoid membrane organization Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 26 (EC:3.1.3.16)
Short name:
AtPP2C26
Gene namesi
Ordered Locus Names:At2g30170
ORF Names:T27E13.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G30170.
TAIRilocus:2060822. AT2G30170.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679551 – 298Probable protein phosphatase 2C 26Add BLAST298

Proteomic databases

PaxDbiO64730.

Expressioni

Gene expression databases

ExpressionAtlasiO64730. baseline and differential.
GenevisibleiO64730. AT.

Interactioni

Protein-protein interaction databases

BioGridi2918. 1 interactor.
IntActiO64730. 1 interactor.
MINTiMINT-8390765.
STRINGi3702.AT2G30170.1.

Structurei

3D structure databases

ProteinModelPortaliO64730.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 295PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST248

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG1379. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000237527.
InParanoidiO64730.
OMAiNLGDSWC.
OrthoDBiEOG09360IQM.
PhylomeDBiO64730.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR001932. PPM-type_phosphatase_dom.
SMARTiView protein in SMART
SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiView protein in PROSITE
PS51746. PPM_2. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: O64730-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAIPVTRMMV PHAIPSLRLS HPNPSRVDFL CRCAPSEIQP LRPELSLSVG
60 70 80 90 100
IHAIPHPDKV EKGGEDAFFV SSYRGGVMAV ADGVSGWAEQ DVDPSLFSKE
110 120 130 140 150
LMANASRLVD DQEVRYDPGF LIDKAHTATT SRGSATIILA MLEEVGILKI
160 170 180 190 200
GNVGDCGLKL LREGQIIFAT APQEHYFDCP YQLSSEGSAQ TYLDASFSIV
210 220 230 240 250
EVQKGDVIVM GSDGLFDNVF DHEIVSIVTK HTDVAESSRL LAEVASSHSR
260 270 280 290
DTEFESPYAL EARAKGFDVP LWKKVLGKKL TGGKLDDVTV IVAKVVSS
Length:298
Mass (Da):32,285
Last modified:June 1, 2002 - v2
Checksum:i52327F83126D89F5
GO
Isoform 2 (identifier: O64730-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-77: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:221
Mass (Da):23,886
Checksum:i65E5747759CB349B
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0367651 – 77Missing in isoform 2. CuratedAdd BLAST77

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004165 Genomic DNA. Translation: AAC16955.2.
CP002685 Genomic DNA. Translation: AEC08354.1.
CP002685 Genomic DNA. Translation: AEC08355.1.
CP002685 Genomic DNA. Translation: ANM61563.1.
AF370298 mRNA. Translation: AAK44113.1.
AY063046 mRNA. Translation: AAL34220.1.
PIRiT00581.
RefSeqiNP_001077980.1. NM_001084511.3. [O64730-2]
NP_001318317.1. NM_001336244.1.
NP_565696.1. NM_128572.5. [O64730-1]
UniGeneiAt.19566.

Genome annotation databases

EnsemblPlantsiAT2G30170.1; AT2G30170.1; AT2G30170. [O64730-1]
AT2G30170.3; AT2G30170.3; AT2G30170. [O64730-2]
GeneIDi817569.
GrameneiAT2G30170.1; AT2G30170.1; AT2G30170.
AT2G30170.3; AT2G30170.3; AT2G30170.
KEGGiath:AT2G30170.

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiP2C26_ARATH
AccessioniPrimary (citable) accession number: O64730
Secondary accession number(s): A8MQM8, Q94K51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2002
Last modified: August 30, 2017
This is version 107 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families