Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O64730 (P2C26_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 26

Short name=AtPP2C26
EC=3.1.3.16
Gene names
Ordered Locus Names:At2g30170
ORF Names:T27E13.9
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length298 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: O64730-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: O64730-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-77: Missing.
Note: Derived from EST data. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 298298Probable protein phosphatase 2C 26
PRO_0000367955

Regions

Domain46 – 295250PP2C-like

Sites

Metal binding821Manganese 1 By similarity
Metal binding821Manganese 2 By similarity
Metal binding831Manganese 1; via carbonyl oxygen By similarity
Metal binding2131Manganese 2 By similarity
Metal binding2861Manganese 2 By similarity

Natural variations

Alternative sequence1 – 7777Missing in isoform 2.
VSP_036765

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified June 1, 2002. Version 2.
Checksum: 52327F83126D89F5

FASTA29832,285
        10         20         30         40         50         60 
MAIPVTRMMV PHAIPSLRLS HPNPSRVDFL CRCAPSEIQP LRPELSLSVG IHAIPHPDKV 

        70         80         90        100        110        120 
EKGGEDAFFV SSYRGGVMAV ADGVSGWAEQ DVDPSLFSKE LMANASRLVD DQEVRYDPGF 

       130        140        150        160        170        180 
LIDKAHTATT SRGSATIILA MLEEVGILKI GNVGDCGLKL LREGQIIFAT APQEHYFDCP 

       190        200        210        220        230        240 
YQLSSEGSAQ TYLDASFSIV EVQKGDVIVM GSDGLFDNVF DHEIVSIVTK HTDVAESSRL 

       250        260        270        280        290 
LAEVASSHSR DTEFESPYAL EARAKGFDVP LWKKVLGKKL TGGKLDDVTV IVAKVVSS 

« Hide

Isoform 2 [UniParc].

Checksum: 65E5747759CB349B
Show »

FASTA22123,886

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
[4]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC004165 Genomic DNA. Translation: AAC16955.2.
CP002685 Genomic DNA. Translation: AEC08354.1.
CP002685 Genomic DNA. Translation: AEC08355.1.
AF370298 mRNA. Translation: AAK44113.1.
AY063046 mRNA. Translation: AAL34220.1.
PIRT00581.
RefSeqNP_001077980.1. NM_001084511.2. [O64730-2]
NP_565696.1. NM_128572.4. [O64730-1]
UniGeneAt.19566.

3D structure databases

ProteinModelPortalO64730.
SMRO64730. Positions 45-297.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid2918. 1 interaction.
IntActO64730. 1 interaction.
MINTMINT-8390765.
STRING3702.AT2G30170.1-P.

Proteomic databases

PaxDbO64730.
PRIDEO64730.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G30170.1; AT2G30170.1; AT2G30170. [O64730-1]
GeneID817569.
KEGGath:AT2G30170.

Organism-specific databases

TAIRAT2G30170.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000237527.
InParanoidQ94K51.
OMADNVFDHE.
PhylomeDBO64730.

Enzyme and pathway databases

BioCycARA:AT2G30170-MONOMER.
ARA:GQT-463-MONOMER.

Gene expression databases

GenevestigatorO64730.

Family and domain databases

Gene3D3.60.40.10. 2 hits.
InterProIPR001932. PP2C-like_dom.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 2 hits.
ProtoNetSearch...

Entry information

Entry nameP2C26_ARATH
AccessionPrimary (citable) accession number: O64730
Secondary accession number(s): A8MQM8, Q94K51
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2002
Last modified: May 14, 2014
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names