O64718 (C71B9_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome P450 71B9
EC=1.14.-.-

Gene names

Name:	CYP71B9
Ordered Locus Names:	At2g02580
ORF Names:	T8K22.12

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Cofactor	Heme group By similarity.
Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the cytochrome P450 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Ligand	Heme Iron Metal-binding
Molecular function	Monooxygenase Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro monooxygenase activity Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Cytochrome P450 71B9		PRO_0000052087
Regions
	Transmembrane	1 – 21	21	Helical; Potential
Sites
	Metal binding	440	1	Iron (heme axial ligand) By similarity
Experimental info
	Sequence conflict	321	1	P → A in AAL59946. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	O64718 [UniParc]. Last modified August 2, 2002. Version 3. Checksum: 9D23C396410E8E4E	FASTA	500	57,084
	10 20 30 40 50 60 MATIWFLSLL FLCCILLAAF KHKKRRTNQQ QPPSPPGFPI IGNLHQLGEL PHQSLWSLSK 70 80 90 100 110 120 TYGPVMLLKL GSVPTVVVSS SETAKQVLKI NDLHCCSRPS LAGAKELSYN YLDIAFSPFD 130 140 150 160 170 180 DYWKELRRIC VQELFSAKRV HSIQPIKEEE VRKLIVSATE SASQKSPVNL SEKFLDLTVS 190 200 210 220 230 240 VICKAAFSLD FHTSVLNNDG FDKLIHDAFL FLGSFSASNF FPNGGWIIDW LTGLQRRREK 250 260 270 280 290 300 SVKDLDVFYQ QMFDLHKQEN KQGVEDFVDL LLKLEKEETV LGYGKLTRNH VKAILMNVLL 310 320 330 340 350 360 GAINTSAMTM TWAMAELIRN PRVMKKVQSE IRNQMINKSV ITLDDIDHLP YLKMVIKETW 370 380 390 400 410 420 RLHPPVPLLL PREVMSEFEI NGYKIQPKTL LYVNVWAIGR DPDSWKDADM FYPERFMDNN 430 440 450 460 470 480 IDAKGQNFEL LPFGSGRRIC PGMYMGTTMV EFGLANMLYQ FDWEVPDGMV VEDIDMEESP 490 500 GLAVGKKNEL LLVPVKYLGH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC004136 Genomic DNA. Translation: AAC18928.2. CP002685 Genomic DNA. Translation: AEC05601.1. AY072124 mRNA. Translation: AAL59946.1.
IPI	IPI00542798.
PIR	T00605.
RefSeq	NP_178362.1. NM_126314.2.
UniGene	At.41479.
3D structure databases
ProteinModelPortal	O64718.
SMR	O64718. Positions 30-480.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT2G02580.1; AT2G02580.1; AT2G02580.
GeneID	814788.
KEGG	ath:AT2G02580.
Organism-specific databases
GeneFarm	1250. 94.
TAIR	At2g02580.
Phylogenomic databases
eggNOG	COG2124.
HOGENOM	HOG000218629.
InParanoid	O64718.
OMA	AINTSAM.
PhylomeDB	O64718.
ProtClustDB	CLSN2683696.
Gene expression databases
ArrayExpress	O64718.
Genevestigator	O64718.
GermOnline	AT2G02580. Arabidopsis thaliana.
Family and domain databases
Gene3D	1.10.630.10. 1 hit.
InterPro	IPR001128. Cyt_P450. IPR017972. Cyt_P450_CS. IPR002401. Cyt_P450_E_grp-I. [Graphical view]
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00463. EP450I. PR00385. P450.
SUPFAM	SSF48264. Cytochrome_P450. 1 hit.
PROSITE	PS00086. CYTOCHROME_P450. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C71B9_ARATH

Accession

Primary (citable) accession number: O64718
Secondary accession number(s): Q8VYE9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	August 2, 2002
Last modified:	May 1, 2013
This is version 100 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program