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Protein

High mobility group B protein 14

Gene

HMGB14

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi63 – 13270HMG boxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • regulation of transcription, DNA-templated Source: GOC
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
High mobility group B protein 14
Alternative name(s):
Nucleosome/chromatin assembly factor group D 14
Gene namesi
Name:HMGB14
Synonyms:NFD14
Ordered Locus Names:At2g34450
ORF Names:F13P17.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G34450.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151High mobility group B protein 14PRO_0000399939Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei150 – 1501PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO64702.
PRIDEiO64702.

Expressioni

Gene expression databases

GenevisibleiO64702. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G34450.2.

Structurei

3D structure databases

ProteinModelPortaliO64702.
SMRiO64702. Positions 53-132.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HMGB family.Curated
Contains 1 HMG box DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0381. Eukaryota.
COG5648. LUCA.
HOGENOMiHOG000197860.
InParanoidiO64702.
OMAiYTKRMES.
PhylomeDBiO64702.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
[Graphical view]
PfamiPF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: O64702-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTKRAPKSGP LSPSCSGGSS RNLELAVKSS EGARRSTRLR LQPLRKPKTS
60 70 80 90 100
PKKKPVKLQT KMPKKPATAF FFFLDDFRKQ YQEENPDVKS MREIGKTCGE
110 120 130 140 150
KWKTMTYEEK VKYYDIATEK REEFHRAMTE YTKRMESGAH DESETDSDYS

E
Length:151
Mass (Da):17,499
Last modified:June 1, 2002 - v2
Checksum:i1BDCB99C1ED68327
GO
Isoform 2 (identifier: O64702-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     93-93: E → EV

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:152
Mass (Da):17,598
Checksum:iA6C8D43EC12B9D45
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei93 – 931E → EV in isoform 2. CuratedVSP_039946

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004077 Genomic DNA. Translation: AAC26692.2.
AC004481 Genomic DNA. Translation: AAM14948.1.
CP002685 Genomic DNA. Translation: AEC08975.1.
CP002685 Genomic DNA. Translation: AEC08976.1.
AK118955 mRNA. Translation: BAC43535.1.
BT005660 mRNA. Translation: AAO64080.1.
AY084626 mRNA. Translation: AAM61189.1.
PIRiT02332.
RefSeqiNP_001031480.1. NM_001036403.1. [O64702-2]
NP_565788.1. NM_128997.2. [O64702-1]
UniGeneiAt.37803.

Genome annotation databases

EnsemblPlantsiAT2G34450.1; AT2G34450.1; AT2G34450. [O64702-1]
GeneIDi818008.
KEGGiath:AT2G34450.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004077 Genomic DNA. Translation: AAC26692.2.
AC004481 Genomic DNA. Translation: AAM14948.1.
CP002685 Genomic DNA. Translation: AEC08975.1.
CP002685 Genomic DNA. Translation: AEC08976.1.
AK118955 mRNA. Translation: BAC43535.1.
BT005660 mRNA. Translation: AAO64080.1.
AY084626 mRNA. Translation: AAM61189.1.
PIRiT02332.
RefSeqiNP_001031480.1. NM_001036403.1. [O64702-2]
NP_565788.1. NM_128997.2. [O64702-1]
UniGeneiAt.37803.

3D structure databases

ProteinModelPortaliO64702.
SMRiO64702. Positions 53-132.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G34450.2.

Proteomic databases

PaxDbiO64702.
PRIDEiO64702.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G34450.1; AT2G34450.1; AT2G34450. [O64702-1]
GeneIDi818008.
KEGGiath:AT2G34450.

Organism-specific databases

TAIRiAT2G34450.

Phylogenomic databases

eggNOGiKOG0381. Eukaryota.
COG5648. LUCA.
HOGENOMiHOG000197860.
InParanoidiO64702.
OMAiYTKRMES.
PhylomeDBiO64702.

Miscellaneous databases

PROiO64702.

Gene expression databases

GenevisibleiO64702. AT.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
[Graphical view]
PfamiPF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: cv. Columbia.
  5. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).

Entry informationi

Entry nameiHMG14_ARATH
AccessioniPrimary (citable) accession number: O64702
Secondary accession number(s): Q2V430
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: June 1, 2002
Last modified: November 11, 2015
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.