UniProtKB - O64645 (SOC1_ARATH)
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Protein
MADS-box protein SOC1
Gene
SOC1
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transcription activator active in flowering time control. May integrate signals from the photoperiod, vernalization and autonomous floral induction pathways. Can modulate class B and C homeotic genes expression. When associated with AGL24, mediates effect of gibberellins on flowering under short-day conditions, and regulates the expression of LEAFY (LFY), which links floral induction and floral development.4 Publications
GO - Molecular functioni
- protein dimerization activity Source: InterPro
- RNA polymerase II regulatory region sequence-specific DNA binding Source: InterPro
- transcription factor activity, sequence-specific DNA binding Source: TAIR
- transcription factor binding Source: UniProtKB
GO - Biological processi
- cell differentiation Source: UniProtKB-KW
- flower development Source: TAIR
- maintenance of inflorescence meristem identity Source: TAIR
- positive regulation of flower development Source: TAIR
- positive regulation of transcription, DNA-templated Source: UniProtKB
- positive regulation of transcription from RNA polymerase II promoter Source: InterPro
- protein import into nucleus, translocation Source: UniProtKB
- response to cold Source: TAIR
- response to gibberellin Source: UniProtKB
- transcription, DNA-templated Source: UniProtKB-KW
Keywordsi
| Molecular function | Activator, Developmental protein, DNA-binding |
| Biological process | Differentiation, Flowering, Transcription, Transcription regulation |
Names & Taxonomyi
| Protein namesi | Recommended name: MADS-box protein SOC1Alternative name(s): Agamous-like MADS-box protein AGL20 Protein SUPPRESSOR OF CONSTANS OVEREXPRESSION 1 |
| Gene namesi | Name:SOC1 Synonyms:AGL20 Ordered Locus Names:At2g45660 ORF Names:F17K2.19 |
| Organismi | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic identifieri | 3702 [NCBI] |
| Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
| Proteomesi |
|
Organism-specific databases
| Araporti | AT2G45660. |
| TAIRi | locus:2005522. AT2G45660. |
Pathology & Biotechi
Disruption phenotypei
Plants are late-flowering.1 Publication
Mutagenesis
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| Mutagenesisi | 24 | R → K in sso36; suppression of early flowering time mediated by SOC1 over-expression. 1 Publication | 1 | |
| Mutagenesisi | 34 | E → K in sso11; partial suppression of early flowering time mediated by SOC1 overexpression. 1 Publication | 1 | |
| Mutagenesisi | 113 | G → E in sso4; partial suppression of early flowering time mediated by SOC1 overexpression. 1 Publication | 1 |
PTM / Processingi
Molecule processing
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| ChainiPRO_0000199486 | 1 – 214 | MADS-box protein SOC1Add BLAST | 214 |
Proteomic databases
| PaxDbi | O64645. |
| PRIDEi | O64645. |
Expressioni
Tissue specificityi
Widely expressed. Not found in the apical meristem of short-day grown plants in vegetative stage.
Developmental stagei
Rapidly up-regulated in apical meristems during the transition to flowering. Transiently expressed in inflorescence meristem. Re-appears in stage 3 flowers, in the central dome that later will develop into stamens and carpels.1 Publication
Inductioni
Up-regulated by gibberellins, vernalization and under long-day conditions. Gradual increase during vegetative growth. Induced by AGL24 at the shoot apex at the floral transitional stage. Repressed by SVP during the early stages of flower development. Inhibited by AP1 in emerging floral meristems (PubMed:17428825, PubMed:18339670, PubMed:19656343). Repressed by SHL to prevent flowering (PubMed:25281686).4 Publications
Gene expression databases
| ExpressionAtlasi | O64645. baseline and differential. |
| Genevisiblei | O64645. AT. |
Interactioni
Subunit structurei
Forms a heterodimer with AGL24 through MADS-box domain. Interacts with AGL15, AGL16 and AGL19.2 Publications
Binary interactionsi
GO - Molecular functioni
- protein dimerization activity Source: InterPro
- transcription factor binding Source: UniProtKB
Protein-protein interaction databases
| BioGridi | 4510. 35 interactors. |
| DIPi | DIP-33799N. |
| IntActi | O64645. 35 interactors. |
| STRINGi | 3702.AT2G45660.1. |
Structurei
3D structure databases
| ProteinModelPortali | O64645. |
| SMRi | O64645. |
| ModBasei | Search... |
| MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| Domaini | 3 – 57 | MADS-boxPROSITE-ProRule annotationAdd BLAST | 55 | |
| Domaini | 87 – 177 | K-boxPROSITE-ProRule annotationAdd BLAST | 91 |
Phylogenomic databases
| eggNOGi | KOG0014. Eukaryota. COG5068. LUCA. |
| HOGENOMi | HOG000155301. |
| InParanoidi | O64645. |
| OMAi | YEAANMM. |
| OrthoDBi | EOG0936106C. |
| PhylomeDBi | O64645. |
Family and domain databases
| CDDi | cd00265. MADS_MEF2_like. 1 hit. |
| Gene3Di | 3.40.1810.10. 1 hit. |
| InterProi | View protein in InterPro IPR033896. MADS_MEF2-like. IPR002487. TF_Kbox. IPR002100. TF_MADSbox. |
| Pfami | View protein in Pfam PF01486. K-box. 1 hit. PF00319. SRF-TF. 1 hit. |
| PRINTSi | PR00404. MADSDOMAIN. |
| SMARTi | View protein in SMART SM00432. MADS. 1 hit. |
| SUPFAMi | SSF55455. SSF55455. 1 hit. |
| PROSITEi | View protein in PROSITE PS51297. K_BOX. 1 hit. PS00350. MADS_BOX_1. 1 hit. PS50066. MADS_BOX_2. 1 hit. |
Sequencei
Sequence statusi: Complete.
O64645-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVRGKTQMKR IENATSRQVT FSKRRNGLLK KAFELSVLCD AEVSLIIFSP
60 70 80 90 100
KGKLYEFASS NMQDTIDRYL RHTKDRVSTK PVSEENMQHL KYEAANMMKK
110 120 130 140 150
IEQLEASKRK LLGEGIGTCS IEELQQIEQQ LEKSVKCIRA RKTQVFKEQI
160 170 180 190 200
EQLKQKEKAL AAENEKLSEK WGSHESEVWS NKNQESTGRG DEESSPSSEV
210
ETQLFIGLPC SSRK
Sequence databases
| Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC003680 Genomic DNA. Translation: AAC06175.1. CP002685 Genomic DNA. Translation: AEC10583.1. AY007726 mRNA. Translation: AAG16297.1. AF385731 mRNA. Translation: AAK60321.1. AY093967 mRNA. Translation: AAM16228.1. |
| PIRi | T00879. |
| RefSeqi | NP_182090.1. NM_130128.4. |
| UniGenei | At.25546. |
Genome annotation databases
| EnsemblPlantsi | AT2G45660.1; AT2G45660.1; AT2G45660. |
| GeneIDi | 819174. |
| Gramenei | AT2G45660.1; AT2G45660.1; AT2G45660. |
| KEGGi | ath:AT2G45660. |
Similar proteinsi
Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:| 100% | UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry. |
| 90% | UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence). |
| 50% | UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster. |
Entry informationi
| Entry namei | SOC1_ARATH | |
| Accessioni | O64645Primary (citable) accession number: O64645 | |
| Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 5, 2001 |
| Last sequence update: | August 1, 1998 | |
| Last modified: | July 5, 2017 | |
| This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
| Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
| Annotation program | Plant Protein Annotation Program | |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names
