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Protein

MADS-box protein SOC1

Gene

SOC1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transcription activator active in flowering time control. May integrate signals from the photoperiod, vernalization and autonomous floral induction pathways. Can modulate class B and C homeotic genes expression. When associated with AGL24, mediates effect of gibberellins on flowering under short-day conditions, and regulates the expression of LEAFY (LFY), which links floral induction and floral development.4 Publications

GO - Molecular functioni

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • flower development Source: TAIR
  • maintenance of inflorescence meristem identity Source: TAIR
  • positive regulation of flower development Source: TAIR
  • positive regulation of transcription, DNA-templated Source: UniProtKB
  • positive regulation of transcription from RNA polymerase II promoter Source: InterPro
  • protein import into nucleus, translocation Source: UniProtKB
  • response to cold Source: TAIR
  • response to gibberellin Source: UniProtKB
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding
Biological processDifferentiation, Flowering, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
MADS-box protein SOC1
Alternative name(s):
Agamous-like MADS-box protein AGL20
Protein SUPPRESSOR OF CONSTANS OVEREXPRESSION 1
Gene namesi
Name:SOC1
Synonyms:AGL20
Ordered Locus Names:At2g45660
ORF Names:F17K2.19
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G45660.
TAIRilocus:2005522. AT2G45660.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Disruption phenotypei

Plants are late-flowering.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi24R → K in sso36; suppression of early flowering time mediated by SOC1 over-expression. 1 Publication1
Mutagenesisi34E → K in sso11; partial suppression of early flowering time mediated by SOC1 overexpression. 1 Publication1
Mutagenesisi113G → E in sso4; partial suppression of early flowering time mediated by SOC1 overexpression. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001994861 – 214MADS-box protein SOC1Add BLAST214

Proteomic databases

PaxDbiO64645.
PRIDEiO64645.

Expressioni

Tissue specificityi

Widely expressed. Not found in the apical meristem of short-day grown plants in vegetative stage.

Developmental stagei

Rapidly up-regulated in apical meristems during the transition to flowering. Transiently expressed in inflorescence meristem. Re-appears in stage 3 flowers, in the central dome that later will develop into stamens and carpels.1 Publication

Inductioni

Up-regulated by gibberellins, vernalization and under long-day conditions. Gradual increase during vegetative growth. Induced by AGL24 at the shoot apex at the floral transitional stage. Repressed by SVP during the early stages of flower development. Inhibited by AP1 in emerging floral meristems (PubMed:17428825, PubMed:18339670, PubMed:19656343). Repressed by SHL to prevent flowering (PubMed:25281686).4 Publications

Gene expression databases

ExpressionAtlasiO64645. baseline and differential.
GenevisibleiO64645. AT.

Interactioni

Subunit structurei

Forms a heterodimer with AGL24 through MADS-box domain. Interacts with AGL15, AGL16 and AGL19.2 Publications

Binary interactionsi

Show more details

GO - Molecular functioni

  • protein dimerization activity Source: InterPro
  • transcription factor binding Source: UniProtKB

Protein-protein interaction databases

BioGridi4510. 35 interactors.
DIPiDIP-33799N.
ELMiO64645.
IntActiO64645. 35 interactors.
STRINGi3702.AT2G45660.1.

Structurei

3D structure databases

ProteinModelPortaliO64645.
SMRiO64645.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 57MADS-boxPROSITE-ProRule annotationAdd BLAST55
Domaini87 – 177K-boxPROSITE-ProRule annotationAdd BLAST91

Phylogenomic databases

eggNOGiKOG0014. Eukaryota.
COG5068. LUCA.
HOGENOMiHOG000155301.
InParanoidiO64645.
OMAiYEAANMM.
OrthoDBiEOG0936106C.
PhylomeDBiO64645.

Family and domain databases

CDDicd00265. MADS_MEF2_like. 1 hit.
Gene3Di3.40.1810.10. 1 hit.
InterProiView protein in InterPro
IPR033896. MADS_MEF2-like.
IPR002487. TF_Kbox.
IPR002100. TF_MADSbox.
PfamiView protein in Pfam
PF01486. K-box. 1 hit.
PF00319. SRF-TF. 1 hit.
PRINTSiPR00404. MADSDOMAIN.
SMARTiView protein in SMART
SM00432. MADS. 1 hit.
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiView protein in PROSITE
PS51297. K_BOX. 1 hit.
PS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O64645-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRGKTQMKR IENATSRQVT FSKRRNGLLK KAFELSVLCD AEVSLIIFSP
60 70 80 90 100
KGKLYEFASS NMQDTIDRYL RHTKDRVSTK PVSEENMQHL KYEAANMMKK
110 120 130 140 150
IEQLEASKRK LLGEGIGTCS IEELQQIEQQ LEKSVKCIRA RKTQVFKEQI
160 170 180 190 200
EQLKQKEKAL AAENEKLSEK WGSHESEVWS NKNQESTGRG DEESSPSSEV
210
ETQLFIGLPC SSRK
Length:214
Mass (Da):24,533
Last modified:August 1, 1998 - v1
Checksum:iB4D39151DE541F8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003680 Genomic DNA. Translation: AAC06175.1.
CP002685 Genomic DNA. Translation: AEC10583.1.
AY007726 mRNA. Translation: AAG16297.1.
AF385731 mRNA. Translation: AAK60321.1.
AY093967 mRNA. Translation: AAM16228.1.
PIRiT00879.
RefSeqiNP_182090.1. NM_130128.4.
UniGeneiAt.25546.

Genome annotation databases

EnsemblPlantsiAT2G45660.1; AT2G45660.1; AT2G45660.
GeneIDi819174.
GrameneiAT2G45660.1; AT2G45660.1; AT2G45660.
KEGGiath:AT2G45660.

Similar proteinsi

Entry informationi

Entry nameiSOC1_ARATH
AccessioniPrimary (citable) accession number: O64645
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 5, 2001
Last sequence update: August 1, 1998
Last modified: August 30, 2017
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names