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Protein

Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g19230

Gene

At2g19230

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei596ATPPROSITE-ProRule annotation1
Active sitei692Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi575 – 583ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g19230 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:At2g19230
ORF Names:F27F23.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G19230.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini25 – 517ExtracellularSequence analysisAdd BLAST493
Transmembranei518 – 538HelicalSequence analysisAdd BLAST21
Topological domaini539 – 877CytoplasmicSequence analysisAdd BLAST339

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000040334025 – 877Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g19230Add BLAST853

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi142N-linked (GlcNAc...)Sequence analysis1
Glycosylationi233N-linked (GlcNAc...)Sequence analysis1
Glycosylationi261N-linked (GlcNAc...)Sequence analysis1
Glycosylationi295N-linked (GlcNAc...)Sequence analysis1
Glycosylationi405N-linked (GlcNAc...)Sequence analysis1
Glycosylationi420N-linked (GlcNAc...)Sequence analysis1
Modified residuei726PhosphoserineBy similarity1
Modified residuei727PhosphothreonineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO64556.

Expressioni

Gene expression databases

GenevisibleiO64556. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G19230.1.

Structurei

3D structure databases

ProteinModelPortaliO64556.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati439 – 462LRR 1Add BLAST24
Repeati463 – 484LRR 2Add BLAST22
Domaini569 – 842Protein kinasePROSITE-ProRule annotationAdd BLAST274

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 2 LRR (leucine-rich) repeats.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IID2. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116550.
InParanoidiO64556.
OrthoDBiEOG09360280.
PhylomeDBiO64556.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR024788. Malectin-like_Carb-bd_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF12819. Malectin_like. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O64556-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNFNFLPLV SFASFVVVLV LVCAQDQSGF VSIDCGIPED SSYYDEKTDI
60 70 80 90 100
KYISDAAFVE SGTIHSIDSK FQKKNLEKQF QKVRSFPEGK KNCYDVQPPQ
110 120 130 140 150
GKGFKYLIRT RFMYGNYDNL GKAPDFDLYL GVNLWDSVTL ENSTTIVTKE
160 170 180 190 200
IIYTLRSDKV HVCLVDKERG TPFLSVLELR LLKNNIYETA SDSLMLYRRW
210 220 230 240 250
DLGATGDLPA RYKDDIFDRF WMPLMFPNFL ILNTSLMIDP TSSNGFLPPS
260 270 280 290 300
VVMSTAVAPM NSSIEQIMVY WEPRDPNWKF YIYIHFAEVE KLPSNETREF
310 320 330 340 350
SVFLNKEQID TTSVFRPSYL YTDTLYVQNP VSGPFLEFVL RQGVKSTRPP
360 370 380 390 400
IMNAIETYRT NEFLDLPTDQ NDVDAIMKIK TKYKVKKNWL GDPCAPFGYP
410 420 430 440 450
WQGINCSYTA NNPPRIISVN LSFSGLTGQI DPVFITLTPL QKLDLSNNRL
460 470 480 490 500
TGTVPDFLAN LPDLTELNLE ENKLTGILPE KLLERSKDGS LSLRVGGNPD
510 520 530 540 550
LCVSDSCRNK KTERKEYIIP SVASVTGLFF LLLALISFWQ FKKRQQSVKT
560 570 580 590 600
GPLDTKRYYK YSEIVEITNN FERVLGQGGF GKVYYGVLRG EQVAIKMLSK
610 620 630 640 650
SSAQGYKEFR AEVELLLRVH HKNLIALIGY CHEGDQMALI YEYIGNGTLG
660 670 680 690 700
DYLSGKNSSI LSWEERLQIS LDAAQGLEYL HNGCKPPIVH RDVKPTNILI
710 720 730 740 750
NEKLQAKIAD FGLSRSFTLE GDSQVSTEVA GTIGYLDPEH YSMQQFSEKS
760 770 780 790 800
DVYSFGVVLL EVITGQPVIS RSRTEENRHI SDRVSLMLSK GDIKSIVDPK
810 820 830 840 850
LGERFNAGLA WKITEVALAC ASESTKTRLT MSQVVAELKE SLCRARTSGD
860 870
SGDISFSEPT EMNVSMTVDP GVLPQPR
Length:877
Mass (Da):99,011
Last modified:March 8, 2011 - v3
Checksum:iD4D1F3E3DFEB3660
GO

Sequence cautioni

The sequence AEC06859 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003058 Genomic DNA. Translation: AAC16453.1.
CP002685 Genomic DNA. Translation: AEC06859.1. Sequence problems.
PIRiT01271.
RefSeqiNP_179513.4. NM_127480.4.
UniGeneiAt.52827.

Genome annotation databases

EnsemblPlantsiAT2G19230.1; AT2G19230.1; AT2G19230.
GeneIDi816440.
GrameneiAT2G19230.1; AT2G19230.1; AT2G19230.
KEGGiath:AT2G19230.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003058 Genomic DNA. Translation: AAC16453.1.
CP002685 Genomic DNA. Translation: AEC06859.1. Sequence problems.
PIRiT01271.
RefSeqiNP_179513.4. NM_127480.4.
UniGeneiAt.52827.

3D structure databases

ProteinModelPortaliO64556.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G19230.1.

Proteomic databases

PaxDbiO64556.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G19230.1; AT2G19230.1; AT2G19230.
GeneIDi816440.
GrameneiAT2G19230.1; AT2G19230.1; AT2G19230.
KEGGiath:AT2G19230.

Organism-specific databases

TAIRiAT2G19230.

Phylogenomic databases

eggNOGiENOG410IID2. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116550.
InParanoidiO64556.
OrthoDBiEOG09360280.
PhylomeDBiO64556.

Miscellaneous databases

PROiO64556.

Gene expression databases

GenevisibleiO64556. AT.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR024788. Malectin-like_Carb-bd_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF12819. Malectin_like. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY2923_ARATH
AccessioniPrimary (citable) accession number: O64556
Secondary accession number(s): F4ISF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: March 8, 2011
Last modified: November 2, 2016
This is version 128 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.