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Protein

Proteasome subunit beta type-1

Gene

PBF1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine protease

Enzyme and pathway databases

ReactomeiR-OSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes)
R-OSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-OSA-349425 Autodegradation of the E3 ubiquitin ligase COP1
R-OSA-5632684 Hedgehog 'on' state
R-OSA-5687128 MAPK6/MAPK4 signaling
R-OSA-5689603 UCH proteinases
R-OSA-5689880 Ub-specific processing proteases
R-OSA-6798695 Neutrophil degranulation
R-OSA-69017 CDK-mediated phosphorylation and removal of Cdc6
R-OSA-69229 Ubiquitin-dependent degradation of Cyclin D1
R-OSA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit beta type-1 (EC:3.4.25.1)
Alternative name(s):
20S proteasome alpha subunit F
20S proteasome subunit beta-6
Gene namesi
Name:PBF1
Ordered Locus Names:Os09g0505600, LOC_Os09g32800
ORF Names:OsJ_29931Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus, Proteasome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001480391 – 221Proteasome subunit beta type-1Add BLAST221

Proteomic databases

PaxDbiO64464

Expressioni

Gene expression databases

ExpressionAtlasiO64464 differential
GenevisibleiO64464 OS

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel (By similarity).By similarity

Protein-protein interaction databases

STRINGi39947.LOC_Os09g32800.1

Structurei

3D structure databases

ProteinModelPortaliO64464
SMRiO64464
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1B family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0179 Eukaryota
COG0638 LUCA
HOGENOMiHOG000091081
InParanoidiO64464
KOiK02732
OMAiEHRFNPY
OrthoDBiEOG09360LMI

Family and domain databases

Gene3Di3.60.20.10, 1 hit
InterProiView protein in InterPro
IPR029055 Ntn_hydrolases_N
IPR035202 Proteasome_beta1
IPR016050 Proteasome_bsu_CS
IPR001353 Proteasome_sua/b
IPR023333 Proteasome_suB-type
PANTHERiPTHR11599:SF55 PTHR11599:SF55, 1 hit
PfamiView protein in Pfam
PF00227 Proteasome, 1 hit
SUPFAMiSSF56235 SSF56235, 1 hit
PROSITEiView protein in PROSITE
PS00854 PROTEASOME_BETA_1, 1 hit
PS51476 PROTEASOME_BETA_2, 1 hit

Sequencei

Sequence statusi: Complete.

O64464-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRGDWVYE NNGGTCVAIA GADYCVVAAD TRLSVGYNIL TRDHSKICEL
60 70 80 90 100
ADKCALASSG FQGDIKALHK NLAARELLYQ HQHNKRMSCP AMAQLLSNTL
110 120 130 140 150
YYKRFFPYYA FNVLGGLDSE GKGCVFTYDA VGSYERTGYS AQGTGSALIM
160 170 180 190 200
PVLDNQLKSP SPLLLPARDA VTPLSETEAV DLVKDVFASA TERDIYTGDK
210 220
LEIVVINKAG TKREYIDLRK D
Length:221
Mass (Da):24,282
Last modified:August 1, 1998 - v1
Checksum:iF040EE0C2CEA5C64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014058 mRNA Translation: BAA28276.1
AC108753 Genomic DNA No translation available.
AP008215 Genomic DNA Translation: BAF25517.1
AP014965 Genomic DNA Translation: BAT08852.1
CM000146 Genomic DNA Translation: EAZ45289.1
AK060884 mRNA Translation: BAG87594.1
AK103136 mRNA Translation: BAG95912.1
RefSeqiXP_015611664.1, XM_015756178.1
UniGeneiOs.3736

Genome annotation databases

EnsemblPlantsiOs09t0505600-01; Os09t0505600-01; Os09g0505600
GeneIDi4347507
GrameneiOs09t0505600-01; Os09t0505600-01; Os09g0505600
KEGGiosa:4347507

Similar proteinsi

Entry informationi

Entry nameiPSB1_ORYSJ
AccessioniPrimary (citable) accession number: O64464
Secondary accession number(s): Q0J0L6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: August 1, 1998
Last modified: May 23, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

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