Reviewed, UniProtKB/Swiss-Prot O64459 (UGPA_PYRPY)

Names and origin

Protein names	Recommended name:     UTP--glucose-1-phosphate uridylyltransferase     EC=2.7.7.9 Alternative name(s):     UDP-glucose pyrophosphorylase       Short name=UGPase       Short name=UDPGP
Organism	Pyrus pyrifolia (Japanese pear) (Pyrus serotina)
Taxonomic identifier	3767 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids I › Rosales › Rosaceae › Maloideae › Pyrus

Protein attributes

Sequence length	471 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Plays a central role as a glucosyl donor in cellular metabolic pathways.
Catalytic activity	UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the UDPGP type 1 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UTP:glucose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 471	471	UTP--glucose-1-phosphate uridylyltransferase		PRO_0000185761

Sequences

	Sequence		Length	Mass (Da)
	O64459-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: CE5523CE35E13B40	FASTA	471	51,845
	10 20 30 40 50 60 MAAVATGNVD KLKSDVASLS QISENEKNGF INLVSRYVSG EEAQHVEWSK IQTPTDEVVV 70 80 90 100 110 120 PYDGLAPTPE DPEEIKKLLD KLVVLKLNGG LGTTMGCTGP KSVIEVRNGL TFLDLIVIQI 130 140 150 160 170 180 ENLNNKYGSC VPLLLMNSFN THDDTQKIVE KYSKSNVQIH TFNQSQYPRL VVEDFSPLPS 190 200 210 220 230 240 KGQTGKDGWY PPGHGDVFPS LKNSGKLDLL LSQGKEYVFI ANSDNLGAVV DLKILHHLIQ 250 260 270 280 290 300 KKNEYCMEVT PKTLADVKGG TLISYEGRVQ LLEIAQVPDQ HVNEFKSIEK FKIFNTNNLW 310 320 330 340 350 360 VNLNAIKRLV EADALKMEII PNPKEVDGVK VLQLETAAGA AIRFFNHAIG INVPRSRFLP 370 380 390 400 410 420 VKATSDLLLV QSDLYTLQDG FVTRNSARKN PENPTIELGP EFKKVGSYLS RFKSIPSILE 430 440 450 460 470 LESLKVSGDV WFGAGVVLKG KVTITAKSGV KLEIPDNAVI ANKDINGPED L

References

[1]

"Molecular cloning and nucleotide sequencing of a cDNA encoding UDP-glucose pyrophosphorylase of Japanese pear (Pyrus pyrifolia Nakai)." Kiyozumi D., Ishimizu T., Nakanishi T., Sakiyama F., Norioka S. Plant Gene Register PGR99-006 Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Nijisseiki. Tissue: Pollen.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB013353 mRNA. Translation: BAA25917.1.
3D structure databases
SMR	O64459. Positions 8-471.
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.7.7.9. 276500.
Family and domain databases
InterPro	IPR002618. UDPGP_trans. IPR016267. UDPGP_trans_sub. [Graphical view]
PANTHER	PTHR11952. UDPGP_trans. 1 hit.
Pfam	PF01704. UDPGP. 1 hit. [Graphical view]
PIRSF	PIRSF000806. UDPGP. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UGPA_PYRPY

Accession

Primary (citable) accession number: O64459

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	August 1, 1998
Last modified:	June 16, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)