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O64240 (VG50_BPMD2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase

EC=1.17.4.2
Alternative name(s):
Gp50
Gene names
Name:50
OrganismMycobacterium phage D29 (Mycobacteriophage D29) [Complete proteome]
Taxonomic identifier28369 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridaeL5likevirus
Virus hostMycobacterium [TaxID: 1763]

Protein attributes

Sequence length693 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.

Cofactor

Adenosylcobalamin By similarity.

Sequence similarities

Belongs to the class II ribonucleoside-triphosphate reductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 693693Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase
PRO_0000221430

Sites

Active site3751 By similarity
Active site3771 By similarity

Amino acid modifications

Disulfide bond90 ↔ 386Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
O64240 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 148B752C15EC561F

FASTA69377,250
        10         20         30         40         50         60 
MTEGEIPWGP TGELVYNRTY SRVKPDGTRE TWPETVERVV SGNLALVDSR YQLPGEREDL 

        70         80         90        100        110        120 
LRLMREFKIL PAGRHLWASG VKNAQHLFNC WVSGWTEKPS DHFEFTFMRL MEGGGVGANY 

       130        140        150        160        170        180 
SNRFLADYPH VKQELEVHIV CDEDHDDYAD LAEAGQLSSR YDSDWVDAFV IEDSREGWAA 

       190        200        210        220        230        240 
ALVDLIDTHY RDDVAHKERV YDVSRVRAAG RKLKTFGGTA SGPVPLAKML TEVSEILSRC 

       250        260        270        280        290        300 
AREGEQYRFE DGGALTGLDA MEIDHAIAQC VVAGGVRRSA RMAMMHWADW QVETFTNIKQ 

       310        320        330        340        350        360 
DSGSHWTTNI SVEVDDAFWS LAKAPVDPLN PRSTKAHRVL KALSEGAVRN GEPGMWDSSL 

       370        380        390        400        410        420 
SNVGEPNEVV CTNPCGEITL EPWEPCNLGH INLAAFVTDA GKTDYIDLIR AHRLMTRFLI 

       430        440        450        460        470        480 
RATFSAVADP KSREVLDRNR RIGVGHLGVA SYLALTGRRY SQAPGDKRFT AFLREMAAEV 

       490        500        510        520        530        540 
DRAAEEFSHE LRIPVPVKKR TVAPTGTIAK MPGVSEGIHP IFSRYFIRRI RFSVLDNDQF 

       550        560        570        580        590        600 
LTASQYAADG YHVEKDQYDK SGNTWVVEIP TKDTLVEAVA ARFGRDAEDI VESANELTLH 

       610        620        630        640        650        660 
QLLAFQALYQ TCWADNAVSF TANVDPDAYE GVDVAADLQR FSGLIKGSTI FPEESFPQAP 

       670        680        690 
YERITKQQYE AAAIKAVADG VDEECANGAC PIK 

« Hide

References

[1]"Genome structure of mycobacteriophage D29: implications for phage evolution."
Ford M.E., Sarkis G.J., Belanger A.E., Hendrix R.W., Hatfull G.F.
J. Mol. Biol. 279:143-164(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF022214 Genomic DNA. Translation: AAC18490.1.
PIRG72805.
RefSeqNP_046865.1. NC_001900.1.

3D structure databases

ProteinModelPortalO64240.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1261592.

Family and domain databases

InterProIPR000788. RNR_lg_C.
IPR013345. RTP_Rdtase_AdoCbl-dep.
[Graphical view]
PfamPF02867. Ribonuc_red_lgC. 2 hits.
[Graphical view]
TIGRFAMsTIGR02505. RTPR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameVG50_BPMD2
AccessionPrimary (citable) accession number: O64240
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families