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Protein

Ribonucleoside-diphosphate reductase subunit beta

Gene

bnrdF

Organism
Bacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).By similarity

Miscellaneous

This gene has an intron within which is encoded yosQ, a putative homing endonuclease.

Catalytic activityi

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.PROSITE-ProRule annotation

Cofactori

Fe cationBy similarityNote: Binds 2 iron ions per subunit.By similarity

Pathwayi: DNA replication

This protein is involved in the pathway DNA replication, which is part of Genetic information processing.
View all proteins of this organism that are known to be involved in the pathway DNA replication and in Genetic information processing.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi66Iron 1PROSITE-ProRule annotation1
Metal bindingi97Iron 1PROSITE-ProRule annotation1
Metal bindingi97Iron 2By similarity1
Metal bindingi101Iron 1PROSITE-ProRule annotation1
Active sitei105PROSITE-ProRule annotation1
Metal bindingi164Iron 2By similarity1
Metal bindingi198Iron 2By similarity1
Metal bindingi201Iron 2By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processDNA replication
LigandIron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00326

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleoside-diphosphate reductase subunit beta (EC:1.17.4.1)
Alternative name(s):
Ribonucleotide reductase small subunit
Gene namesi
Name:bnrdF
Synonyms:yosP
OrganismiBacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta)
Taxonomic identifieri66797 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridaeSpbetavirus
Virus hostiBacillus pumilus (Bacillus mesentericus) [TaxID: 1408]
Bacillus subtilis [TaxID: 1423]
Proteomesi
  • UP000009091 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003890111 – 329Ribonucleoside-diphosphate reductase subunit betaAdd BLAST329

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.By similarity

Structurei

3D structure databases

ProteinModelPortaliO64174
SMRiO64174
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00526
OrthoDBiVOG090000AL

Family and domain databases

CDDicd01049 RNRR2, 1 hit
Gene3Di1.10.620.20, 1 hit
InterProiView protein in InterPro
IPR009078 Ferritin-like_SF
IPR012348 RNR-like
IPR026494 RNR_NrdF
IPR033909 RNR_small
IPR030475 RNR_small_AS
IPR000358 RNR_small_fam
PANTHERiPTHR23409 PTHR23409, 1 hit
PfamiView protein in Pfam
PF00268 Ribonuc_red_sm, 1 hit
PIRSFiPIRSF000355 NrdB, 1 hit
SUPFAMiSSF47240 SSF47240, 1 hit
TIGRFAMsiTIGR04171 RNR_1b_NrdF, 1 hit
PROSITEiView protein in PROSITE
PS00368 RIBORED_SMALL, 1 hit

Sequencei

Sequence statusi: Complete.

O64174-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKIYDAANW SKHEDDFTQM FYNQNVKQFW LPEEIALNGD LLTWKYLGKN
60 70 80 90 100
EQDTYMKVLA GLTLLDTEQG NTGMPIVAEH VDGHQRKAVL NFMAMMENAV
110 120 130 140 150
HAKSYSNIFL TLAPTEQINE VFEWVKNNRF LQKKARTIVS VYKTIKKNDE
160 170 180 190 200
ISLFKGMVAS VFLESFLFYS GFYYPLYFYG QGKLMQSGEI INLIIRDEAI
210 220 230 240 250
HGVYVGLLAQ EIYKKQTPQK QKELYAWALN LLQELYENEL EYTEDVYDQV
260 270 280 290 300
GLAPDVKKFI RYNANKALNN LGFDHWFEEE DVNPIVINGL NTKTKSHDFF
310 320
STKGNGYKKA TVEPLKDSDF IFTEKGCIQ
Length:329
Mass (Da):38,181
Last modified:August 1, 1998 - v1
Checksum:iEC36E9DFC12BD269
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020713 Genomic DNA Translation: AAC13135.1
PIRiT12926
RefSeqiNP_046714.1, NC_001884.1

Genome annotation databases

GeneIDi1261446
KEGGivg:1261446

Similar proteinsi

Entry informationi

Entry nameiBNRDF_BPSPB
AccessioniPrimary (citable) accession number: O64174
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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