Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

AimR transcriptional regulator

Gene

aimR

Organism
Bacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcriptional regulator which is part of the latency-replication switch system that decides at the onset of infection whether to replicate and lyse the host or to lysogenize (latency) and keep the host viable. Activates the transcription of the aimX locus. Transcriptional activation of aimX seems to lead to the productive viral replication (lytic cycle), aimX possibly acting as a regulatory non-coding RNA.By similarity

GO - Biological processi

Keywordsi

Molecular functionActivator
Biological processLatency-replication decision, Transcription, Transcription regulation, Viral latency

Names & Taxonomyi

Protein namesi
Recommended name:
AimR transcriptional regulatorBy similarity
Alternative name(s):
Arbitrium communication peptide receptorBy similarity
YopK protein
Gene namesi
Name:aimRBy similarity
Synonyms:yopK
OrganismiBacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta)
Taxonomic identifieri66797 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridaeSpbetavirus
Virus hostiBacillus pumilus (Bacillus mesentericus) [TaxID: 1408]
Bacillus subtilis [TaxID: 1423]
Proteomesi
  • UP000009091 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004392571 – 386AimR transcriptional regulatorAdd BLAST386

Interactioni

Subunit structurei

Homodimer. Interacts with the viral arbitrium peptide, this interaction changes the oligomeric state of AimR from an active dimer to an inactive monomer leading to lysogeny.By similarity

Structurei

3D structure databases

ProteinModelPortaliO64094.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi155 – 158Poly-LeuSequence analysis4
Compositional biasi380 – 386Poly-LeuSequence analysis7

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiView protein in InterPro
IPR011990. TPR-like_helical_dom.

Sequencei

Sequence statusi: Complete.

O64094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELIRIAMKK DLENDNSLMN KWATVAGLKN PNPLYDFLNH DGKTFNEFSS
60 70 80 90 100
IVNIVKSQYP DREYELMKDY CLNLDVKTKA ARSALEYADA NMFFEIEDVL
110 120 130 140 150
IDSMISCSNM KSKEYGKVYK IHRELSNSVI TEFEAVKRLG KLNIKTPEMN
160 170 180 190 200
SFSRLLLLYH YLSTGNFSPM AQLIKQIDLS EISENMYIRN TYQTRVHVLM
210 220 230 240 250
SNIKLNENSL EECREYSKKA LESTNILRFQ VFSYLTIGNS LLFSNYELAQ
260 270 280 290 300
ENFLKGLSIS VQNENYNMIF QQALCFLNNV WRKENKWINF ESDSIMDLQE
310 320 330 340 350
QAHCFINFNE NSKAKEVLDK LDLLVHNDNE LAMHYYLKGR LEQNKACFYS
360 370 380
SIEYFKKSND KFLIRLPLLE LQKMGENQKL LELLLL
Length:386
Mass (Da):45,320
Last modified:August 1, 1998 - v1
Checksum:i3C341F5D43A0CDE1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020713 Genomic DNA. Translation: AAC13054.1.
PIRiT12845.
RefSeqiNP_046633.1. NC_001884.1.

Genome annotation databases

GeneIDi1261404.
KEGGivg:1261404.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiAIMR_BPSPB
AccessioniPrimary (citable) accession number: O64094
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2017
Last sequence update: August 1, 1998
Last modified: July 5, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome