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O63915 (COX3_MYXGL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
Encoded onMitochondrion
OrganismMyxine glutinosa (Atlantic hagfish)
Taxonomic identifier7769 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataCyclostomataHyperotretiMyxiniformesMyxinidaeMyxininaeMyxine

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 261261Cytochrome c oxidase subunit 3
PRO_0000183811

Regions

Transmembrane15 – 3521Helical; Potential
Transmembrane38 – 5821Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane197 – 21721Helical; Potential
Transmembrane239 – 25921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O63915 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 97A9448357E6BD82

FASTA26130,052
        10         20         30         40         50         60 
MTKQMHAFHM VNPSPWPLTG AASAFMLTSG LAMWFHKHSN TLIFLSMILM LLTMYQWWRD 

        70         80         90        100        110        120 
ITREGTFQGH HTSLVQKSLR YGMILFIVSE VCFFFGFFWT FYHSSLSPSP DLGMMWPPKG 

       130        140        150        160        170        180 
VIPLDPFEIP LLNTAILLGS GVSVTWAHHS LMEKTHKDMV ISLSITIILG IYFTLLQGME 

       190        200        210        220        230        240 
YFNSTFNISD NAYGSTFFVA TGFHGGHVII GTLFLTVCLL RQLMFHFTSS HHFGFEAAAW 

       250        260 
YWHFVDVVWL FLFISIYWWG S 

« Hide

References

[1]"The mitochondrial DNA molecule of the hagfish (Myxine glutinosa) and vertebrate phylogeny."
Rasmussen A.S., Janke A., Arnason U.
J. Mol. Evol. 46:382-388(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete mitochondrial genome of the hagfish Myxine glutinosa: unique features of the control region."
Delarbre C., Rasmussen A.S., Arnason U., Gachelin G.
J. Mol. Evol. 53:634-641(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y15184 Genomic DNA. Translation: CAA75483.1.
AJ404477 Genomic DNA. Translation: CAC20655.1.
RefSeqNP_073279.1. NC_002639.1.

3D structure databases

ProteinModelPortalO63915.
SMRO63915. Positions 1-261.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID802345.

Organism-specific databases

CTD4514.

Phylogenomic databases

HOVERGENHBG016686.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_MYXGL
AccessionPrimary (citable) accession number: O63915
Entry history
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families