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Protein

Cytochrome c oxidase subunit 2

Gene

COII

Organism
Glis glis (Fat dormouse) (Myoxus glis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotationSAAS annotation, Transport
LigandCopperUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 2UniRule annotationSAAS annotation
Gene namesi
Name:COIIImported
Encoded oniMitochondrionImported
OrganismiGlis glis (Fat dormouse) (Myoxus glis)Imported
Taxonomic identifieri41261 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciuromorphaGliridaeGlirinaeGlis

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO63901
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 91COX2_TMInterPro annotationAdd BLAST91
Domaini92 – 225COX2_CUAInterPro annotationAdd BLAST134

Sequence similaritiesi

Belongs to the cytochrome c oxidase subunit 2 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG012727

Family and domain databases

CDDicd13912 CcO_II_C, 1 hit
Gene3Di1.10.287.90, 1 hit
2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR002429 CcO_II-like_C
IPR034210 CcO_II_C
IPR001505 Copper_CuA
IPR008972 Cupredoxin
IPR014222 Cyt_c_oxidase_su2
IPR011759 Cyt_c_oxidase_su2_TM_dom
IPR036257 Cyt_c_oxidase_su2_TM_sf
PfamiView protein in Pfam
PF00116 COX2, 1 hit
PF02790 COX2_TM, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
SSF81464 SSF81464, 1 hit
TIGRFAMsiTIGR02866 CoxB, 1 hit
PROSITEiView protein in PROSITE
PS00078 COX2, 1 hit
PS50857 COX2_CUA, 1 hit
PS50999 COX2_TM, 1 hit

Sequencei

Sequence statusi: Complete.

O63901-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYPFELGFQ DATSPIMEEL LHFHDHALMI VFLISSLVLY IIILMLTTKL
60 70 80 90 100
THTSTMDAQE GETIWTILSA IILIMIALPS LRILYMMDEL NNPTLTVKTV
110 120 130 140 150
GHQWYWSYQY TGYEDLSFDS YMVPTTDLKP GELRLLEVDN RVVLPMEMPV
160 170 180 190 200
RVLISSEDVL HSWAVPSLGL KTDAIPGRLN QATLTSTRPG LYYGQCSEIC
210 220
GSNHSFMPIV LELVPLKYFE NWSLSMI
Length:227
Mass (Da):25,855
Last modified:August 1, 1998 - v1
Checksum:iE0E36A555A5116B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001562 Genomic DNA Translation: CAA04833.1
PIRiT11392
RefSeqiNP_007513.1, NC_001892.1

Genome annotation databases

GeneIDi808190

Similar proteinsi

Entry informationi

Entry nameiO63901_GLIGL
AccessioniPrimary (citable) accession number: O63901
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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