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Protein

Cytochrome c oxidase subunit 2

Gene
N/A
Organism
Florometra serratissima (common feather star)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotationSAAS annotation, Transport
LigandCopperUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 2UniRule annotationSAAS annotation
Encoded oniMitochondrionImported
OrganismiFlorometra serratissima (common feather star)Imported
Taxonomic identifieri73431 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataPelmatozoaCrinoideaArticulataComatulidaAntedonidaeFlorometra

Subcellular locationi

  • Mitochondrion inner membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 49HelicalSequence analysisAdd BLAST24
Transmembranei61 – 87HelicalSequence analysisAdd BLAST27

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO63590.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 91COX2_TMInterPro annotationAdd BLAST91
Domaini92 – 225COX2_CUAInterPro annotationAdd BLAST134

Sequence similaritiesi

Belongs to the cytochrome c oxidase subunit 2 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

CDDicd13912. CcO_II_C. 1 hit.
Gene3Di2.60.40.420. 1 hit.
InterProiView protein in InterPro
IPR002429. CcO_II-like_C.
IPR034210. CcO_II_C.
IPR001505. Copper_CuA.
IPR008972. Cupredoxin.
IPR014222. Cyt_c_oxidase_su2.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
PfamiView protein in Pfam
PF00116. COX2. 1 hit.
PF02790. COX2_TM. 1 hit.
SUPFAMiSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
TIGRFAMsiTIGR02866. CoxB. 1 hit.
PROSITEiView protein in PROSITE
PS00078. COX2. 1 hit.
PS50857. COX2_CUA. 1 hit.
PS50999. COX2_TM. 1 hit.

Sequencei

Sequence statusi: Complete.

O63590-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATWLQLGFQ DASSPLMEEL IYFHDYILVV LVLITIIVFY GLFSLLFIVN
60 70 80 90 100
TDRFFLDSQG VETVWTVVPA FILVFIAFPS LQLLYLIDEI NDPCLTIKAL
110 120 130 140 150
GHQWYWSYEY TDYCNLDFDS YMVFTDDLTF GSLRLLEVDN RVIVPSQNSI
160 170 180 190 200
RVLVSSSDVL HSWAIPSLGI KMDAVPGRLN QVTFLCPRSG VFYGQCSEIC
210 220
GASHSFMPIV IESIPFNTFE NWVYNFINN
Length:229
Mass (Da):26,270
Last modified:August 1, 1998 - v1
Checksum:iEA4E6C53777686A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF049132 Genomic DNA. Translation: AAD05076.1.
PIRiT11119.
RefSeqiNP_008385.1. NC_001878.1.

Genome annotation databases

GeneIDi808160.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO63590_9ECHI
AccessioniPrimary (citable) accession number: O63590
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: June 7, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)