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Protein

Preprotein translocase subunit SECY, chloroplastic

Gene

SECY

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

The central subunit of the protein translocation channel SecYE. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Preprotein translocase subunit SECY, chloroplastic
Alternative name(s):
CpSecY
Gene namesi
Name:SECY
Synonyms:CSY1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei144 – 16421HelicalSequence analysisAdd
BLAST
Transmembranei194 – 21421HelicalSequence analysisAdd
BLAST
Transmembranei243 – 26321HelicalSequence analysisAdd
BLAST
Transmembranei270 – 29021HelicalSequence analysisAdd
BLAST
Transmembranei297 – 31721HelicalSequence analysisAdd
BLAST
Transmembranei330 – 35021HelicalSequence analysisAdd
BLAST
Transmembranei384 – 40421HelicalSequence analysisAdd
BLAST
Transmembranei417 – 43721HelicalSequence analysisAdd
BLAST
Transmembranei482 – 50221HelicalSequence analysisAdd
BLAST
Transmembranei505 – 52521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 553Preprotein translocase subunit SECY, chloroplasticPRO_0000031996
Transit peptidei1 – ?ChloroplastSequence analysis

Proteomic databases

PaxDbiO63066.

Interactioni

Subunit structurei

Component of the plastid Sec protein translocase complex, which is composed of at least SECY and SECE.By similarity

Protein-protein interaction databases

STRINGi4577.GRMZM5G809546_P01.

Structurei

3D structure databases

ProteinModelPortaliO63066.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecY/SEC61-alpha family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IHRV. Eukaryota.
COG0201. LUCA.
HOGENOMiHOG000080585.

Family and domain databases

Gene3Di1.10.3370.10. 1 hit.
HAMAPiMF_01465. SecY.
InterProiIPR026593. SecY.
IPR002208. SecY/SEC61-alpha.
IPR030659. SecY_CS.
IPR023201. SecY_su_dom.
[Graphical view]
PANTHERiPTHR10906. PTHR10906. 1 hit.
PfamiPF00344. SecY. 1 hit.
[Graphical view]
SUPFAMiSSF103491. SSF103491. 1 hit.
TIGRFAMsiTIGR00967. 3a0501s007. 1 hit.
PROSITEiPS00755. SECY_1. 1 hit.
PS00756. SECY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O63066-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTATTTPPQ CWRGLPALAR APPPLSSPLR PRAVAAAAPI YPLRRRIAIT
60 70 80 90 100
TTRGRRGTLD CSPRCTLETA GPGFDPLGLY EEGSNSLSRS PLSTFFGIMA
110 120 130 140 150
PVFGSSSGGG ASREKASGRG AAAAIEDSSI DIGDFFKGPL PGKFLKLLGF
160 170 180 190 200
LALSRLGVYI PLGGVNREAF AGNLDQNSLL GTLDSFSGGG IGRLGICSLG
210 220 230 240 250
IVPFINAQIV FQLLAQLYPK LQDLQRKEGE AGRKKVLQYT RYASVGFAIV
260 270 280 290 300
QAIGQVLYLR PYVNDFSTEW VLTSVTLLTL GSVFTTFIGE RISDLKLGNG
310 320 330 340 350
TSLLIFTSII SYLPASFGRT VAQAFQDGNY VGLLTIILSF LLLVLGIVYV
360 370 380 390 400
QEAERKIPLN YASRYSSRTG ELQRSAYLPF KVNSSGVMPI IFSTSSLALP
410 420 430 440 450
GTLARFSGLD FLKKAAIALN PGGALYLPTN VLLIAFFNYY YTFLQLDPDD
460 470 480 490 500
LSEQLKRQGA SIPLVRPGKS TAAYIKTVLN RISVLGSAFL AVLAAGPSLV
510 520 530 540 550
EQTSHLTAFR GFAGTSVLIL VGCATDTARK VQAEIISQKY KNIEFYDVNR

FGQ
Length:553
Mass (Da):59,354
Last modified:August 1, 1998 - v1
Checksum:i641A3E5D3F340417
GO

Sequence cautioni

The sequence AAB96657.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF039304 mRNA. Translation: AAC05019.1.
AF039305 Genomic DNA. Translation: AAB96657.1. Sequence problems.
PIRiT01416.
T01432.
UniGeneiZm.94586.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF039304 mRNA. Translation: AAC05019.1.
AF039305 Genomic DNA. Translation: AAB96657.1. Sequence problems.
PIRiT01416.
T01432.
UniGeneiZm.94586.

3D structure databases

ProteinModelPortaliO63066.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4577.GRMZM5G809546_P01.

Proteomic databases

PaxDbiO63066.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IHRV. Eukaryota.
COG0201. LUCA.
HOGENOMiHOG000080585.

Family and domain databases

Gene3Di1.10.3370.10. 1 hit.
HAMAPiMF_01465. SecY.
InterProiIPR026593. SecY.
IPR002208. SecY/SEC61-alpha.
IPR030659. SecY_CS.
IPR023201. SecY_su_dom.
[Graphical view]
PANTHERiPTHR10906. PTHR10906. 1 hit.
PfamiPF00344. SecY. 1 hit.
[Graphical view]
SUPFAMiSSF103491. SSF103491. 1 hit.
TIGRFAMsiTIGR00967. 3a0501s007. 1 hit.
PROSITEiPS00755. SECY_1. 1 hit.
PS00756. SECY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A SecY homologue is required for the elaboration of the chloroplast thylakoid membrane and for normal chloroplast gene expression."
    Roy L.M., Barkan A.
    J. Cell Biol. 141:385-395(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
    Strain: cv. B73.

Entry informationi

Entry nameiSECY_MAIZE
AccessioniPrimary (citable) accession number: O63066
Secondary accession number(s): O47005
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: August 1, 1998
Last modified: February 17, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.