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O62826

- TRPC2_BOVIN

UniProt

O62826 - TRPC2_BOVIN

Protein

Short transient receptor potential channel 2 homolog

Gene

TRPC2

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Aug 1998)
      Previous versions | rss
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    Functioni

    Thought to form a receptor-activated calcium permeant cation channel.By similarity

    GO - Molecular functioni

    1. calcium channel activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Calcium channel, Ion channel

    Keywords - Biological processi

    Calcium transport, Ion transport, Transport

    Keywords - Ligandi

    Calcium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Short transient receptor potential channel 2 homolog
    Short name:
    TrpC2
    Alternative name(s):
    Transient receptor protein 2
    Short name:
    TRP-2
    Short name:
    bTrp2
    Gene namesi
    Name:TRPC2
    Synonyms:TRP2
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 432432Short transient receptor potential channel 2 homologPRO_0000215309Add
    BLAST

    Proteomic databases

    PRIDEiO62826.

    Interactioni

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000015344.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1 – 2121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei52 – 7221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei96 – 11621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei162 – 18221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG257288.

    Family and domain databases

    InterProiIPR005821. Ion_trans_dom.
    IPR005458. TRPC2_channel.
    IPR002153. TRPC_channel.
    [Graphical view]
    PANTHERiPTHR10117. PTHR10117. 1 hit.
    PTHR10117:SF6. PTHR10117:SF6. 1 hit.
    PfamiPF00520. Ion_trans. 1 hit.
    [Graphical view]
    PRINTSiPR01097. TRNSRECEPTRP.
    PR01643. TRPCHANNEL2.

    Sequencei

    Sequence statusi: Complete.

    O62826-1 [UniParc]FASTAAdd to Basket

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    MVILSLYLAA FTLRLLLAGL AHKHCRDAPD GAACHYFTSA ERSEWRTEDP    50
    QFLAEVLFAV TSMLSFTRLA SILPAHESLG TLQISMGRMI DDMIRFMFIL 100
    MIILTAFLCG LNNIYVPYQE TERLGNFNET FQFLFWTMFG MEEHSVVDMP 150
    QFLVPEFVGR ALYGIFTIVM VIVLLNMLIA MITNSFQKIE DAADVEWKFA 200
    RSKLYLSYFR EGLTLPVPFN ILPSPKAIFY LLRRVFRFIC CCHFCCKTKK 250
    PDYPPIPTFA NPGAGAGPGE GERGSYRLRV IKALVQRYIE TAQREFEETR 300
    RKDLGNRLTE LTKTVSRLQS EVAGVQRAVV EAGPRRPPGG ASVLSRYITR 350
    VRNSFQNLGP PIPETPELTV PATVGTQESS EIGLPDAGGA QAPASGESGP 400
    SSPAHVLVHR EQESEGAGDL PQEADLGAKE GT 432
    Length:432
    Mass (Da):48,057
    Last modified:August 1, 1998 - v1
    Checksum:i9BA438C22E98B02C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ006304 mRNA. Translation: CAA06964.1.
    UniGeneiBt.2872.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ006304 mRNA. Translation: CAA06964.1 .
    UniGenei Bt.2872.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000015344.

    Proteomic databases

    PRIDEi O62826.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi NOG257288.

    Family and domain databases

    InterProi IPR005821. Ion_trans_dom.
    IPR005458. TRPC2_channel.
    IPR002153. TRPC_channel.
    [Graphical view ]
    PANTHERi PTHR10117. PTHR10117. 1 hit.
    PTHR10117:SF6. PTHR10117:SF6. 1 hit.
    Pfami PF00520. Ion_trans. 1 hit.
    [Graphical view ]
    PRINTSi PR01097. TRNSRECEPTRP.
    PR01643. TRPCHANNEL2.
    ProtoNeti Search...

    Publicationsi

    1. "Structure and mRNA expression of a bovine trp homologue related to mammalian trp2 transcripts."
      Wissenbach U., Schroth G., Philipp S., Flockerzi V.
      FEBS Lett. 429:61-66(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Testis.

    Entry informationi

    Entry nameiTRPC2_BOVIN
    AccessioniPrimary (citable) accession number: O62826
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 20, 2001
    Last sequence update: August 1, 1998
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3