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Protein

Sperm surface protein Sp17

Gene

SPA17

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm surface protein Sp17
Alternative name(s):
Sperm autoantigenic protein 17
Gene namesi
Name:SPA17
Synonyms:SP17
OrganismiMonodelphis domestica (Gray short-tailed opossum)
Taxonomic identifieri13616 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
Proteomesi
  • UP000002280 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001813431 – 179Sperm surface protein Sp17Add BLAST179

Expressioni

Tissue specificityi

Testis- and sperm-specific.

Gene expression databases

BgeeiENSMODG00000003723.

Interactioni

Subunit structurei

Homodimer. May interact with ROPN1 (By similarity).By similarity

Protein-protein interaction databases

STRINGi13616.ENSMODP00000004559.

Structurei

3D structure databases

ProteinModelPortaliO62771.
SMRiO62771.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 172IQPROSITE-ProRule annotationAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi124 – 132Poly-Glu9

Sequence similaritiesi

Contains 1 IQ domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IX7J. Eukaryota.
ENOG410XXA6. LUCA.
HOGENOMiHOG000059525.
HOVERGENiHBG003879.
InParanoidiO62771.

Family and domain databases

InterProiIPR003117. cAMP_dep_PK_reg_su_I/II_a/b.
IPR000048. IQ_motif_EF-hand-BS.
IPR012105. Sp17.
[Graphical view]
PfamiPF00612. IQ. 1 hit.
PF02197. RIIa. 1 hit.
[Graphical view]
PIRSFiPIRSF016533. Sp17. 1 hit.
SMARTiSM00015. IQ. 1 hit.
SM00394. RIIa. 1 hit.
[Graphical view]
SUPFAMiSSF47391. SSF47391. 1 hit.
PROSITEiPS50096. IQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O62771-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFENLLEKR
60 70 80 90 100
EKTNFDPAEW GAKVDDRFYN NHAFKDEPPE KSETQKIQPE KVAIEKETMP
110 120 130 140 150
QETVKEKETQ VSFVEEPTEE PQKEEEEEED EEDLEGLLVR EGMQDAAVKI
160 170
QAVFRGHKTR KEYLKKRDST DETADENNE
Length:179
Mass (Da):20,864
Last modified:August 1, 1998 - v1
Checksum:iCADDC13CEC66A00E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF054290 mRNA. Translation: AAC08025.1.
RefSeqiNP_001028164.1. NM_001032992.1.
UniGeneiMdm.224.

Genome annotation databases

GeneIDi554229.
KEGGimdo:554229.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF054290 mRNA. Translation: AAC08025.1.
RefSeqiNP_001028164.1. NM_001032992.1.
UniGeneiMdm.224.

3D structure databases

ProteinModelPortaliO62771.
SMRiO62771.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi13616.ENSMODP00000004559.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi554229.
KEGGimdo:554229.

Organism-specific databases

CTDi53340.

Phylogenomic databases

eggNOGiENOG410IX7J. Eukaryota.
ENOG410XXA6. LUCA.
HOGENOMiHOG000059525.
HOVERGENiHBG003879.
InParanoidiO62771.

Gene expression databases

BgeeiENSMODG00000003723.

Family and domain databases

InterProiIPR003117. cAMP_dep_PK_reg_su_I/II_a/b.
IPR000048. IQ_motif_EF-hand-BS.
IPR012105. Sp17.
[Graphical view]
PfamiPF00612. IQ. 1 hit.
PF02197. RIIa. 1 hit.
[Graphical view]
PIRSFiPIRSF016533. Sp17. 1 hit.
SMARTiSM00015. IQ. 1 hit.
SM00394. RIIa. 1 hit.
[Graphical view]
SUPFAMiSSF47391. SSF47391. 1 hit.
PROSITEiPS50096. IQ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSP17_MONDO
AccessioniPrimary (citable) accession number: O62771
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.