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Protein

Sperm surface protein Sp17

Gene

SPA17

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity).By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm surface protein Sp17
Alternative name(s):
Sperm autoantigenic protein 17
Gene namesi
Name:SPA17
Synonyms:SP17
OrganismiMonodelphis domestica (Gray short-tailed opossum)
Taxonomic identifieri13616 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
Proteomesi
  • UP000002280 Componenti: Unplaced

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001813431 – 179Sperm surface protein Sp17Add BLAST179

Expressioni

Tissue specificityi

Testis- and sperm-specific.

Interactioni

Subunit structurei

Homodimer. May interact with ROPN1 (By similarity).By similarity

Protein-protein interaction databases

STRINGi13616.ENSMODP00000004559.

Structurei

3D structure databases

ProteinModelPortaliO62771.
SMRiO62771.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 172IQPROSITE-ProRule annotationAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi124 – 132Poly-Glu9

Phylogenomic databases

eggNOGiENOG410IX7J. Eukaryota.
ENOG410XXA6. LUCA.
HOGENOMiHOG000059525.
HOVERGENiHBG003879.
InParanoidiO62771.

Family and domain databases

InterProiView protein in InterPro
IPR003117. cAMP_dep_PK_reg_su_I/II_a/b.
IPR000048. IQ_motif_EF-hand-BS.
IPR012105. Sp17.
PANTHERiPTHR10699:SF22. PTHR10699:SF22. 1 hit.
PfamiView protein in Pfam
PF00612. IQ. 1 hit.
PF02197. RIIa. 1 hit.
PIRSFiPIRSF016533. Sp17. 1 hit.
SMARTiView protein in SMART
SM00015. IQ. 1 hit.
SM00394. RIIa. 1 hit.
SUPFAMiSSF47391. SSF47391. 1 hit.
PROSITEiView protein in PROSITE
PS50096. IQ. 1 hit.

Sequencei

Sequence statusi: Complete.

O62771-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFENLLEKR
60 70 80 90 100
EKTNFDPAEW GAKVDDRFYN NHAFKDEPPE KSETQKIQPE KVAIEKETMP
110 120 130 140 150
QETVKEKETQ VSFVEEPTEE PQKEEEEEED EEDLEGLLVR EGMQDAAVKI
160 170
QAVFRGHKTR KEYLKKRDST DETADENNE
Length:179
Mass (Da):20,864
Last modified:August 1, 1998 - v1
Checksum:iCADDC13CEC66A00E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF054290 mRNA. Translation: AAC08025.1.
RefSeqiNP_001028164.1. NM_001032992.1.
UniGeneiMdm.224.

Genome annotation databases

GeneIDi554229.
KEGGimdo:554229.

Similar proteinsi

Entry informationi

Entry nameiSP17_MONDO
AccessioniPrimary (citable) accession number: O62771
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: August 1, 1998
Last modified: August 30, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome