Protein hunchback

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• metal ion binding Source: UniProtKB-KW
• RNA polymerase II distal enhancer sequence-specific DNA binding Source: EnsemblMetazoa
• transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Source: EnsemblMetazoa

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• negative regulation of transcription from RNA polymerase II promoter Source: EnsemblMetazoa
• neuroblast fate determination Source: EnsemblMetazoa
• positive regulation of transcription from RNA polymerase II promoter Source: EnsemblMetazoa
• regulation of development, heterochronic Source: InterPro
• regulation of transcription involved in anterior/posterior axis specification Source: EnsemblMetazoa
• terminal region determination Source: EnsemblMetazoa
• torso signaling pathway Source: EnsemblMetazoa
• transcription, DNA-templated Source: InterPro

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Zinc finger

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the ‘Sequence’ section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MQNWETTATT NYEQHNAWYN SMFAANIKQE PGHHLDGNSV ASSPRQSPIP 
        60         70         80         90        100
STNHLEQFLK QQQQHQQQPM DTLCAMTPSP SQNDQNSLQH YDANLQQQLL 
       110        120        130        140        150
QQQQYQQHFQ AAQQQHHHHH HLMGGFNPLT PPGLPNPMQH FYGGNLRPSP 
       160        170        180        190        200
QPTPTSASTI APVAVATGSS EKLQALTPPM DVTPPKSPAK SSQSNIEPEK 
       210        220        230        240        250
EHDQMSNSSE DMKYMAESED DDTNIRMPIY NSHGKMKNYK CKTCGVVAIT 
       260        270        280        290        300
KVDFWAHTRT HMKPDKILQC PKCPFVTEFK HHLEYHIRKH KNQKPFQCDK 
       310        320        330        340        350
CSYTCVNKSM LNSHRKSHSS VYQYRCADCD YATKYCHSFK LHLRKYGHKP 
       360        370        380        390        400
GMVLDEDGTP NPSLVIDVYG TRRGPKSKNG GPIASGGSGS GSRKSNVAAV 
       410        420        430        440        450
APQQQQSQPA QPVATSHLSA ALQGFPLVQS NSAPPAASPV LPLPASPAKS 
       460        470        480        490        500
VASVEQTPSL PSPANLLPPL ASLLQQNRNM AFFPYWNLNL QMLAAQQQAA 
       510        520        530        540        550
VLAQLSPRMR EQLQQQNQQQ SDNEEEDQDD EYERKSVDSA MDLSQGTPVK 
       560        570        580        590        600
EDEQQQQPQQ PLAMNLKVEE EATPLMSSSN ASRRKGRVLK LDTLLQLRSE 
       610        620        630        640        650
AMTSPEQLKV PSTPMPTASS PIAGRKPMPE EHCSGTSSAD ESMERPHVRQ 
       660        670        680        690        700
ANTSASSTAS SSGNSSNASS NSNGNSSSNS SSNGTTSAVA APPSGTPAAA 
       710        720        730        740        750
GAIYECKYCD IFFKDAVLYT IHMGYHSCDD VFKCNMCGEK CDGPVGLFVH 

MARNAHS                                             

Sequence databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Documents

1. Drosophila
   Drosophila: entries, gene names and cross-references to FlyBase
2. SIMILARITY comments
   Index of protein domains and families