Ant2

Functionⁱ

GO - Molecular functionⁱ

ATP:ADP antiporter activity Source: FlyBase

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

ADP transport Source: FlyBase
ATP transport Source: FlyBase
regulation of mitochondrial membrane permeability Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	TransportUniRule annotationSAAS annotation

Biological process

TransportUniRule annotationSAAS annotation

Enzyme and pathway databases

Reactomeⁱ	R-DME-1268020 Mitochondrial protein import R-DME-422356 Regulation of insulin secretion

Reactomeⁱ

R-DME-1268020 Mitochondrial protein import
R-DME-422356 Regulation of insulin secretion

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ADP/ATP translocaseImported Submitted name: AT02195pImported Submitted name: AT07206pImported Submitted name: Adenine nucleotide translocase 2, isoform AImported Submitted name: Adenine nucleotide translocase 2, isoform BImported Submitted name: Adenine nucleotide translocase 2, isoform CImported Submitted name: GM13259pImported
Gene namesⁱ	Name:Ant2Imported Synonyms:ANT2Imported, Ant2-RAImported, Ant2-RBImported, Dmel\CG1683Imported, l(1)G0126Imported, l(1)G0247Imported, l(1)G0386Imported ORF Names:CG1683Imported, Dmel_CG1683Imported
Organismⁱ	Drosophila melanogaster (Fruit fly)Imported
Taxonomic identifierⁱ	7227 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophila › Sophophora › melanogaster group › melanogaster subgroup
Proteomesⁱ	UP000000803 Componentⁱ: Chromosome X

Organism-specific databases

Drosophila genome database More...FlyBaseⁱ	FBgn0025111 Ant2

FlyBaseⁱ

FBgn0025111 Ant2

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	181 – 200	HelicalSequence analysisAdd BLAST		20
Transmembraneⁱ	220 – 240	HelicalSequence analysisAdd BLAST		21

Keywords - Cellular componentⁱ

Membrane

Expressionⁱ

Gene expression databases

Bgeeⁱ	FBgn0025111

Bgeeⁱ

FBgn0025111

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	7227.FBpp0073282

STRINGⁱ

7227.FBpp0073282

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	16 – 108	SolcarPROSITE-ProRule annotationAdd BLAST	93
Repeatⁱ	121 – 210	SolcarPROSITE-ProRule annotationAdd BLAST	90
Repeatⁱ	221 – 306	SolcarPROSITE-ProRule annotationAdd BLAST	86

Sequence similaritiesⁱ

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domainⁱ

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG0749 Eukaryota ENOG410XNW0 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000011543
HOGENOMⁱ	HOG000245391
KEGG Orthology (KO) More...KOⁱ	K05863
OMAⁱ	QHASKTI
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ULB

Family and domain databases

Gene3Dⁱ	1.50.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR002113 Aden_trnslctor IPR002067 Mit_carrier IPR018108 Mitochondrial_sb/sol_carrier IPR023395 Mt_carrier_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00153 Mito_carr, 3 hits
PRINTSⁱ	PR00927 ADPTRNSLCASE PR00926 MITOCARRIER
SUPFAMⁱ	SSF103506 SSF103506, 1 hit
PROSITEⁱ	View protein in PROSITE PS50920 SOLCAR, 3 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

O62526-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGDEGGGGGH GKGDLKSFLM DFMMGGVSAA IAKTAVAPIE RVKLILQVQE 
        60         70         80         90        100
VSKQIAADQR YKGIVDCFIR IPKEQGFSSF WRGNLANVIR YFPTQALNFA 
       110        120        130        140        150
FKDVYKSVFL GGVDKHKQFW RHFAGNLASG GAAGATSLCF VYPLDFARTR 
       160        170        180        190        200
LAADVGKGGN REFNGLIDCL MKVIKSDGPI GLYRGFIVSV QGIVIYRAAY 
       210        220        230        240        250
FGFYDTCRDF LPNPKSTPFY VSWAIAQVVT TVAGIASYPF DTVRRRMMMQ 
       260        270        280        290        300
SGLKKSEMVY KNTAHCWLVI AKQEGIGAFF KGALSNIIRG TGGALVLALY 

DEMKKYF

Length:307

Mass (Da):33,744

Last modified:August 1, 1998 - v1

Checksum:ⁱ3D6B3DFD82061C0C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE014298 Genomic DNA Translation: AAF47956.1 AE014298 Genomic DNA Translation: AAO41648.1 BT044582 mRNA Translation: ACI31282.1 BT044583 mRNA Translation: ACI31283.1 BT088432 mRNA Translation: ACR40400.1 AE014298 Genomic DNA Translation: AGB95275.1 Y10618 Genomic DNA Translation: CAA71629.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001259432.1, NM_001272503.1 NP_511110.1, NM_078555.4 NP_788898.1, NM_176725.3
UniGeneⁱ	Dm.21507

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0073425; FBpp0073281; FBgn0025111 FBtr0073426; FBpp0073282; FBgn0025111 FBtr0333963; FBpp0306086; FBgn0025111
GeneIDⁱ	32008
KEGGⁱ	dme:Dmel_CG1683
UCSC genome browser More...UCSCⁱ	CG1683-RA d. melanogaster

Protein	Similar proteins		Species	Score	Length
O62526	Uncharacterized protein		DROER		307
GM11287		DROSE		307
Uncharacterized protein		DROWI		307
GA14170		DROMI		307
Uncharacterized protein		DROYA		307
+18

Protein	Similar proteins		Species	Score	Length
O62526	ADP,ATP carrier protein 2	)	YEAST		318
K7_Pet9p		YEASK		318
Pet9p		YEASC		318
ADP/ATP carrier		YEAS7		318
PET9-like protein		SACEU		318
+301

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE014298 Genomic DNA Translation: AAF47956.1 AE014298 Genomic DNA Translation: AAO41648.1 BT044582 mRNA Translation: ACI31282.1 BT044583 mRNA Translation: ACI31283.1 BT088432 mRNA Translation: ACR40400.1 AE014298 Genomic DNA Translation: AGB95275.1 Y10618 Genomic DNA Translation: CAA71629.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001259432.1, NM_001272503.1 NP_511110.1, NM_078555.4 NP_788898.1, NM_176725.3
UniGeneⁱ	Dm.21507

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	7227.FBpp0073282

STRINGⁱ

7227.FBpp0073282

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0073425; FBpp0073281; FBgn0025111 FBtr0073426; FBpp0073282; FBgn0025111 FBtr0333963; FBpp0306086; FBgn0025111
GeneIDⁱ	32008
KEGGⁱ	dme:Dmel_CG1683
UCSC genome browser More...UCSCⁱ	CG1683-RA d. melanogaster

Organism-specific databases

CTDⁱ	32008
Drosophila genome database More...FlyBaseⁱ	FBgn0025111 Ant2

Phylogenomic databases

eggNOGⁱ	KOG0749 Eukaryota ENOG410XNW0 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000011543
HOGENOMⁱ	HOG000245391
KEGG Orthology (KO) More...KOⁱ	K05863
OMAⁱ	QHASKTI
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ULB

Enzyme and pathway databases

Reactomeⁱ	R-DME-1268020 Mitochondrial protein import R-DME-422356 Regulation of insulin secretion

Reactomeⁱ

R-DME-1268020 Mitochondrial protein import
R-DME-422356 Regulation of insulin secretion

Miscellaneous databases

ChiTaRSⁱ	Ant2 fly
GenomeRNAiⁱ	32008

Gene expression databases

Bgeeⁱ	FBgn0025111

Bgeeⁱ

FBgn0025111

Family and domain databases

Gene3Dⁱ	1.50.40.10, 1 hit
InterProⁱ	View protein in InterPro IPR002113 Aden_trnslctor IPR002067 Mit_carrier IPR018108 Mitochondrial_sb/sol_carrier IPR023395 Mt_carrier_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00153 Mito_carr, 3 hits
PRINTSⁱ	PR00927 ADPTRNSLCASE PR00926 MITOCARRIER
SUPFAMⁱ	SSF103506 SSF103506, 1 hit
PROSITEⁱ	View protein in PROSITE PS50920 SOLCAR, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	O62526_DROME
Accessionⁱ	O62526Primary (citable) accession number: O62526
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	August 1, 1998
	Last sequence update:	August 1, 1998
	Last modified:	June 20, 2018
	This is version 162 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O62526 (O62526_DROME)

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ADP/ATP translocase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Other locations

Topology

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ