UniProtKB - O62526 (O62526_DROME)
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Protein
Submitted name:
ADP/ATP translocase
Gene
Ant2
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- ATP:ADP antiporter activity Source: FlyBase
GO - Biological processi
- ADP transport Source: FlyBase
- ATP transport Source: FlyBase
- regulation of mitochondrial membrane permeability Source: GO_Central
Keywordsi
Biological process | TransportUniRule annotationSAAS annotation |
Names & Taxonomyi
Protein namesi | Submitted name: ADP/ATP translocaseImportedSubmitted name: AT02195pImportedSubmitted name: AT07206pImportedSubmitted name: Adenine nucleotide translocase 2, isoform AImportedSubmitted name: Adenine nucleotide translocase 2, isoform BImportedSubmitted name: Adenine nucleotide translocase 2, isoform CImportedSubmitted name: GM13259pImported |
Gene namesi | Name:Ant2Imported Synonyms:ANT2Imported, Ant2-RAImported, Ant2-RBImported, Dmel\CG1683Imported, l(1)G0126Imported, l(1)G0247Imported, l(1)G0386Imported ORF Names:CG1683Imported, Dmel_CG1683Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0025111. Ant2. |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 181 – 200 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 220 – 240 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembraneInteractioni
Protein-protein interaction databases
IntActi | O62526. 8 interactors. |
STRINGi | 7227.FBpp0073282. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 16 – 108 | SolcarPROSITE-ProRule annotationAdd BLAST | 93 | |
Repeati | 121 – 210 | SolcarPROSITE-ProRule annotationAdd BLAST | 90 | |
Repeati | 221 – 306 | SolcarPROSITE-ProRule annotationAdd BLAST | 86 |
Sequence similaritiesi
Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation
Keywords - Domaini
RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotationPhylogenomic databases
eggNOGi | KOG0749. Eukaryota. ENOG410XNW0. LUCA. |
GeneTreei | ENSGT00390000011543. |
HOGENOMi | HOG000245391. |
KOi | K05863. |
OMAi | QHASKTI. |
OrthoDBi | EOG091G0ULB. |
Family and domain databases
Gene3Di | 1.50.40.10. 1 hit. |
InterProi | View protein in InterPro IPR002113. Aden_trnslctor. IPR002067. Mit_carrier. IPR018108. Mitochondrial_sb/sol_carrier. IPR023395. Mt_carrier_dom_sf. |
Pfami | View protein in Pfam PF00153. Mito_carr. 3 hits. |
PRINTSi | PR00927. ADPTRNSLCASE. PR00926. MITOCARRIER. |
SUPFAMi | SSF103506. SSF103506. 1 hit. |
PROSITEi | View protein in PROSITE PS50920. SOLCAR. 3 hits. |
i Sequence
Sequence statusi: Complete.
O62526-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGDEGGGGGH GKGDLKSFLM DFMMGGVSAA IAKTAVAPIE RVKLILQVQE
60 70 80 90 100
VSKQIAADQR YKGIVDCFIR IPKEQGFSSF WRGNLANVIR YFPTQALNFA
110 120 130 140 150
FKDVYKSVFL GGVDKHKQFW RHFAGNLASG GAAGATSLCF VYPLDFARTR
160 170 180 190 200
LAADVGKGGN REFNGLIDCL MKVIKSDGPI GLYRGFIVSV QGIVIYRAAY
210 220 230 240 250
FGFYDTCRDF LPNPKSTPFY VSWAIAQVVT TVAGIASYPF DTVRRRMMMQ
260 270 280 290 300
SGLKKSEMVY KNTAHCWLVI AKQEGIGAFF KGALSNIIRG TGGALVLALY
DEMKKYF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014298 Genomic DNA. Translation: AAF47956.1. AE014298 Genomic DNA. Translation: AAO41648.1. BT044582 mRNA. Translation: ACI31282.1. BT044583 mRNA. Translation: ACI31283.1. BT088432 mRNA. Translation: ACR40400.1. AE014298 Genomic DNA. Translation: AGB95275.1. Y10618 Genomic DNA. Translation: CAA71629.1. |
RefSeqi | NP_001259432.1. NM_001272503.1. NP_511110.1. NM_078555.4. NP_788898.1. NM_176725.3. |
UniGenei | Dm.21507. |
Genome annotation databases
EnsemblMetazoai | FBtr0073425; FBpp0073281; FBgn0025111. FBtr0073426; FBpp0073282; FBgn0025111. FBtr0333963; FBpp0306086; FBgn0025111. |
GeneIDi | 32008. |
KEGGi | dme:Dmel_CG1683. |
UCSCi | CG1683-RA. d. melanogaster. |
Similar proteinsi
Entry informationi
Entry namei | O62526_DROME | |
Accessioni | O62526Primary (citable) accession number: O62526 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 1, 1998 |
Last sequence update: | August 1, 1998 | |
Last modified: | March 28, 2018 | |
This is version 160 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |