ID   PAHX_CAEEL              Reviewed;         312 AA.
AC   O62515;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   16-JUN-2009, entry version 51.
DE   RecName: Full=Probable phytanoyl-CoA dioxygenase;
DE            EC=1.14.11.18;
DE   AltName: Full=Phytanoyl-CoA alpha-hydroxylase;
DE            Short=PhyH;
DE   AltName: Full=Phytanic acid oxidase;
GN   ORFNames=ZK550.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;
OC   Rhabditidae; Peloderinae; Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for
RT   investigating biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
CC   -!- CATALYTIC ACTIVITY: Phytanoyl-CoA + 2-oxoglutarate + O(2) = 2-
CC       hydroxyphytanoyl-CoA + succinate + CO(2).
CC   -!- COFACTOR: Iron (By similarity).
CC   -!- COFACTOR: Ascorbate (By similarity).
CC   -!- PATHWAY: Lipid metabolism; fatty acid metabolism.
CC   -!- SIMILARITY: Belongs to the PhyH family.
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DR   EMBL; Z82287; CAB05318.1; -; Genomic_DNA.
DR   EMBL; Z80223; CAB05318.1; JOINED; Genomic_DNA.
DR   EMBL; Z80223; CAB02322.1; -; Genomic_DNA.
DR   EMBL; Z82287; CAB02322.1; JOINED; Genomic_DNA.
DR   PIR; T21397; T21397.
DR   RefSeq; NP_503062.1; -.
DR   UniGene; Cel.11604; -.
DR   Ensembl; ZK550.6; Caenorhabditis elegans.
DR   GeneID; 178503; -.
DR   KEGG; cel:ZK550.6; -.
DR   WormBase; WBGene00014000; ZK550.6.
DR   WormPep; ZK550.6; CE20432.
DR   OMA; O62515; NIMFHGI.
DR   BRENDA; 1.14.11.18; 672.
DR   NextBio; 901392; -.
DR   ArrayExpress; O62515; -.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single d...; IEA:UniProtKB-KW.
DR   GO; GO:0048244; F:phytanoyl-CoA dioxygenase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR008775; Phytyl_CoA_dOase.
DR   Pfam; PF05721; PhyH; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase;
KW   Vitamin C.
FT   CHAIN         1    312       Probable phytanoyl-CoA dioxygenase.
FT                                /FTId=PRO_0000215231.
FT   REGION      142    144       Alpha-ketoglutarate binding (By
FT                                similarity).
FT   METAL       142    142       Iron (By similarity).
FT   METAL       144    144       Iron (By similarity).
FT   METAL       231    231       Iron (By similarity).
FT   BINDING      84     84       Alpha-ketoglutarate (By similarity).
FT   BINDING     124    124       Alpha-ketoglutarate (By similarity).
FT   BINDING     160    160       Alpha-ketoglutarate (By similarity).
FT   BINDING     233    233       Alpha-ketoglutarate (By similarity).
FT   BINDING     242    242       Alpha-ketoglutarate (By similarity).
SQ   SEQUENCE   312 AA;  35720 MW;  6B5A63624FCB70CB CRC64;
     MLGKGVVDYT REGSILSAEQ RRFYEKNGYL LIRNCVPQYE LNRFRQRFQD ICEKKVKAPE
     NMTVMKDISI AKSEFKDGEK AITKIQDFAD DPVLFEYCKY PGVVDVVKDL IGNPKSNLMA
     MHTMLINKPP DNGKLTSRHP MHQDLQYFPF RPADFICCAW TAMEKITRAN GCLVVVPGTH
     KGVLLPHEYP KWEGGVNKAY HGIQDYDTST PRIHVEMEPG DTVFFHPILI HGSGANRTEG
     FRKAISCHYA NDDLCRYVNV EGTTQETLAE EIIEIAKKRL TRYGLDPNTV TLDFADIWRV
     RAREVNGRRS NL
//