Reviewed, UniProtKB/Swiss-Prot O62515 (PAHX_CAEEL)

Names and origin

Protein names

Recommended name:
    Probable phytanoyl-CoA dioxygenase
    EC=1.14.11.18
Alternative name(s):
    Phytanoyl-CoA alpha-hydroxylase
      Short name=PhyH
    Phytanic acid oxidase

Gene names

ORF Names:

ZK550.6

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	312 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Catalytic activity	Phytanoyl-CoA + 2-oxoglutarate + O(2) = 2-hydroxyphytanoyl-CoA + succinate + CO(2).
Cofactor	Iron By similarity. Ascorbate By similarity.
Pathway	Lipid metabolism; fatty acid metabolism.
Sequence similarities	Belongs to the PhyH family.

Ontologies

Keywords
Ligand	Iron Vitamin C
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	L-ascorbic acid binding Inferred from electronic annotation. Source: UniProtKB-KW iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW phytanoyl-CoA dioxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 312	312	Probable phytanoyl-CoA dioxygenase		PRO_0000215231

Sequences

	Sequence		Length	Mass (Da)
	O62515-1 [UniParc]. Last modified May 1, 1999. Version 2. Checksum: 6B5A63624FCB70CB	FASTA	312	35,720
	10 20 30 40 50 60 MLGKGVVDYT REGSILSAEQ RRFYEKNGYL LIRNCVPQYE LNRFRQRFQD ICEKKVKAPE 70 80 90 100 110 120 NMTVMKDISI AKSEFKDGEK AITKIQDFAD DPVLFEYCKY PGVVDVVKDL IGNPKSNLMA 130 140 150 160 170 180 MHTMLINKPP DNGKLTSRHP MHQDLQYFPF RPADFICCAW TAMEKITRAN GCLVVVPGTH 190 200 210 220 230 240 KGVLLPHEYP KWEGGVNKAY HGIQDYDTST PRIHVEMEPG DTVFFHPILI HGSGANRTEG 250 260 270 280 290 300 FRKAISCHYA NDDLCRYVNV EGTTQETLAE EIIEIAKKRL TRYGLDPNTV TLDFADIWRV 310 RAREVNGRRS NL

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z82287, Z80223 Genomic DNA. Translation: CAB05318.1. Z80223, Z82287 Genomic DNA. Translation: CAB02322.1.
PIR	T21397.
RefSeq	NP_503062.1.
UniGene	Cel.11604
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ZK550.6. Caenorhabditis elegans. [Contig view]
GeneID	178503.
KEGG	cel:ZK550.6.
Organism-specific databases
WormBase	WBGene00014000. ZK550.6.
WormPep	ZK550.6. CE20432. [WorfDB]
Gene expression databases
ArrayExpress	O62515.
Family and domain databases
InterPro	IPR008775. Phytyl_CoA_dOase. [Graphical view]
Pfam	PF05721. PhyH. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	901392.

Entry information

Entry name

PAHX_CAEEL

Accession

Primary (citable) accession number: O62515

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	November 4, 2008
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project