Probable phytanoyl-CoA dioxygenase - Caenorhabditis elegans

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Reviewed, UniProtKB/Swiss-Prot O62515 (PAHX_CAEEL)

Last modified June 16, 2009. Version 51. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein names

Recommended name:
    Probable phytanoyl-CoA dioxygenase
    EC=1.14.11.18
Alternative name(s):
    Phytanoyl-CoA alpha-hydroxylase
      Short name=PhyH
    Phytanic acid oxidase

Gene names

ORF Names:

ZK550.6

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	312 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Catalytic activity	Phytanoyl-CoA + 2-oxoglutarate + O₂ = 2-hydroxyphytanoyl-CoA + succinate + CO₂.
Cofactor	Iron By similarity. Ascorbate By similarity.
Pathway	Lipid metabolism; fatty acid metabolism.
Sequence similarities	Belongs to the PhyH family.

Ontologies

Keywords
Ligand	Iron Metal-binding Vitamin C
Molecular function	Dioxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	L-ascorbic acid binding Inferred from electronic annotation. Source: UniProtKB-KW iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Inferred from electronic annotation. Source: UniProtKB-KW phytanoyl-CoA dioxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

312

Probable phytanoyl-CoA dioxygenase

PRO_0000215231

Regions

Region

3

Alpha-ketoglutarate binding By similarity

Sites

Metal binding

1

Iron By similarity

Metal binding

1

Iron By similarity

Metal binding

1

Iron By similarity

Binding site

1

Alpha-ketoglutarate By similarity

Binding site

1

Alpha-ketoglutarate By similarity

Binding site

1

Alpha-ketoglutarate By similarity

Binding site

1

Alpha-ketoglutarate By similarity

Binding site

1

Alpha-ketoglutarate By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

O62515-1 [UniParc].

Last modified May 1, 1999. Version 2.
Checksum: 6B5A63624FCB70CB
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312

35,720

        10         20         30         40         50         60 
MLGKGVVDYT REGSILSAEQ RRFYEKNGYL LIRNCVPQYE LNRFRQRFQD ICEKKVKAPE 

        70         80         90        100        110        120 
NMTVMKDISI AKSEFKDGEK AITKIQDFAD DPVLFEYCKY PGVVDVVKDL IGNPKSNLMA 

       130        140        150        160        170        180 
MHTMLINKPP DNGKLTSRHP MHQDLQYFPF RPADFICCAW TAMEKITRAN GCLVVVPGTH 

       190        200        210        220        230        240 
KGVLLPHEYP KWEGGVNKAY HGIQDYDTST PRIHVEMEPG DTVFFHPILI HGSGANRTEG 

       250        260        270        280        290        300 
FRKAISCHYA NDDLCRYVNV EGTTQETLAE EIIEIAKKRL TRYGLDPNTV TLDFADIWRV 

       310 
RAREVNGRRS NL

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
	Z82287, Z80223 Genomic DNA. Translation: CAB05318.1. Z80223, Z82287 Genomic DNA. Translation: CAB02322.1.
PIR	T21397.
RefSeq	NP_503062.1.
UniGene	Cel.11604
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ZK550.6. Caenorhabditis elegans. [Contig view]
GeneID	178503.
KEGG	cel:ZK550.6.
Organism-specific databases
WormBase	WBGene00014000. ZK550.6.
WormPep	ZK550.6. CE20432. [WorfDB]
Phylogenomic databases
OMA	O62515. NIMFHGI.
Enzyme and pathway databases
BRENDA	1.14.11.18. 672.
Gene expression databases
ArrayExpress	O62515.
Family and domain databases
InterPro	IPR008775. Phytyl_CoA_dOase. [Graphical view]
Pfam	PF05721. PhyH. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	901392.

Entry information

Entry name

PAHX_CAEEL

Accession

Primary (citable) accession number: O62515

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	June 16, 2009
This is version 51 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents