SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O62431

- SYQ_CAEEL

UniProt

O62431 - SYQ_CAEEL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Probable glutamine--tRNA ligase
Gene
ers-1, qrs-5, Y41E3.4
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei502 – 5021ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamine-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutaminyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamine--tRNA ligase (EC:6.1.1.18)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
Name:ers-1
Synonyms:qrs-5
ORF Names:Y41E3.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiY41E3.4a; CE18372; WBGene00001336; qars-1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 786786Probable glutamine--tRNA ligase
PRO_0000195861Add
BLAST

Proteomic databases

PaxDbiO62431.
PRIDEiO62431.

Interactioni

Protein-protein interaction databases

STRINGi6239.Y41E3.4.

Structurei

3D structure databases

ProteinModelPortaliO62431.
SMRiO62431. Positions 2-182, 240-779.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi276 – 28611"HIGH" region
Add
BLAST
Motifi499 – 5035"KMSKS" region

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
GeneTreeiENSGT00550000074972.
HOGENOMiHOG000259233.
InParanoidiO62431.
KOiK01886.
OMAiRMQKRAK.
PhylomeDBiO62431.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF04558. tRNA_synt_1c_R1. 1 hit.
PF04557. tRNA_synt_1c_R2. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O62431-1 [UniParc]FASTAAdd to Basket

« Hide

MATKEELLSL GLSDSKVAET LKNVKLTETI GSIVKLASES GEISKQKGTL    50
LYQLATKLKP QVAAHTPLVV KYIMNDGIKT EPQLSAAIEY LLSHTVKGIQ 100
VPDFEKSCGV GVVVTIDDIE AAVTKVIGQH REKIVAERYS FPAGKLLGEL 150
RALLPWADGA ITKKEVDLRF LELLGPKTAE DLAPKKKEKK PEGPKPSKDA 200
AAAATAPGTK NQKEASPEEF ADGAETMDEL LRTRAHFHKV GENFKQDGYV 250
TTPKTAELLK AHVAAVGGKV VTRFPPEPNG VLHIGHAKAI NINFGYAKAM 300
GGVCNLRFDD TNPEKEEEKF FSAIEDIVHW LGYDPARVTH SSDNFQQLYL 350
WAVKLIQKGL AFVCHQKVEE MRGFEVQLSP WRERPIEENI QLFEDMKNGK 400
FDEGEATLRL KLTLEEGKVD PVAYRIKYVP HHRTGNQWCI YPTYDYTHCL 450
CDSIENITHS LCTKEFQSRR SSYYWLCNAL DIYCPVQWEY GRLNVNYTVV 500
SKRKILKLIT TKTVNDWDDP RLFTLTALRR RGIPSEAINR FVAKLGLTMS 550
QMVIDPHVLD ATVRDYLNIH APRTMAVLEG LKLTIENFSE LNLPSSVDVP 600
DFPSDPTDPR KHSVSVDREI FIEKSDYKPD DSDKSFRRLT PKQAVGLKHI 650
GLVLRFVKEV KDAEGHVTEV VVKAEKLSEK DKPKAFIHWV AKPVSCEVRL 700
YDRLFKSKNP EDAQLVPGGF LSDINPDSLT VVYNALIDQS IAKSKVYDRF 750
QFERIGFFCV DRDSTSSTLV FNRTVMLKDG GASGKN 786
Length:786
Mass (Da):88,262
Last modified:August 1, 1998 - v1
Checksum:iD00F343D845F4B47
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z95559 Genomic DNA. Translation: CAB08998.1.
PIRiT26811.
RefSeqiNP_001255843.1. NM_001268914.1.
UniGeneiCel.7782.

Genome annotation databases

EnsemblMetazoaiY41E3.4a; Y41E3.4a; WBGene00001336.
GeneIDi178415.
KEGGicel:CELE_Y41E3.4.
UCSCiY41E3.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z95559 Genomic DNA. Translation: CAB08998.1 .
PIRi T26811.
RefSeqi NP_001255843.1. NM_001268914.1.
UniGenei Cel.7782.

3D structure databases

ProteinModelPortali O62431.
SMRi O62431. Positions 2-182, 240-779.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.Y41E3.4.

Proteomic databases

PaxDbi O62431.
PRIDEi O62431.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Y41E3.4a ; Y41E3.4a ; WBGene00001336 .
GeneIDi 178415.
KEGGi cel:CELE_Y41E3.4.
UCSCi Y41E3.4. c. elegans.

Organism-specific databases

CTDi 178415.
WormBasei Y41E3.4a ; CE18372 ; WBGene00001336 ; qars-1.

Phylogenomic databases

eggNOGi COG0008.
GeneTreei ENSGT00550000074972.
HOGENOMi HOG000259233.
InParanoidi O62431.
KOi K01886.
OMAi RMQKRAK.
PhylomeDBi O62431.

Miscellaneous databases

NextBioi 901048.
PROi O62431.

Family and domain databases

Gene3Di 1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF04558. tRNA_synt_1c_R1. 1 hit.
PF04557. tRNA_synt_1c_R2. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF50715. SSF50715. 1 hit.
TIGRFAMsi TIGR00440. glnS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiSYQ_CAEEL
AccessioniPrimary (citable) accession number: O62431
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: June 11, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi