Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O62431

- SYQ_CAEEL

UniProt

O62431 - SYQ_CAEEL

Protein

Probable glutamine--tRNA ligase

Gene

ers-1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 Aug 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei502 – 5021ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamine-tRNA ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutaminyl-tRNA aminoacylation Source: InterPro

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glutamine--tRNA ligase (EC:6.1.1.18)
    Alternative name(s):
    Glutaminyl-tRNA synthetase
    Short name:
    GlnRS
    Gene namesi
    Name:ers-1
    Synonyms:qrs-5
    ORF Names:Y41E3.4
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome IV

    Organism-specific databases

    WormBaseiY41E3.4a; CE18372; WBGene00001336; qars-1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 786786Probable glutamine--tRNA ligasePRO_0000195861Add
    BLAST

    Proteomic databases

    PaxDbiO62431.
    PRIDEiO62431.

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.Y41E3.4.

    Structurei

    3D structure databases

    ProteinModelPortaliO62431.
    SMRiO62431. Positions 2-182, 240-779.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi276 – 28611"HIGH" regionAdd
    BLAST
    Motifi499 – 5035"KMSKS" region

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0008.
    GeneTreeiENSGT00550000074972.
    HOGENOMiHOG000259233.
    InParanoidiO62431.
    KOiK01886.
    OMAiRMQKRAK.
    PhylomeDBiO62431.

    Family and domain databases

    Gene3Di1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    InterProiIPR001412. aa-tRNA-synth_I_CS.
    IPR004514. Gln-tRNA-synth.
    IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
    IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR10119. PTHR10119. 1 hit.
    PfamiPF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    PF04558. tRNA_synt_1c_R1. 1 hit.
    PF04557. tRNA_synt_1c_R2. 1 hit.
    [Graphical view]
    PRINTSiPR00987. TRNASYNTHGLU.
    SUPFAMiSSF50715. SSF50715. 1 hit.
    TIGRFAMsiTIGR00440. glnS. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O62431-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATKEELLSL GLSDSKVAET LKNVKLTETI GSIVKLASES GEISKQKGTL    50
    LYQLATKLKP QVAAHTPLVV KYIMNDGIKT EPQLSAAIEY LLSHTVKGIQ 100
    VPDFEKSCGV GVVVTIDDIE AAVTKVIGQH REKIVAERYS FPAGKLLGEL 150
    RALLPWADGA ITKKEVDLRF LELLGPKTAE DLAPKKKEKK PEGPKPSKDA 200
    AAAATAPGTK NQKEASPEEF ADGAETMDEL LRTRAHFHKV GENFKQDGYV 250
    TTPKTAELLK AHVAAVGGKV VTRFPPEPNG VLHIGHAKAI NINFGYAKAM 300
    GGVCNLRFDD TNPEKEEEKF FSAIEDIVHW LGYDPARVTH SSDNFQQLYL 350
    WAVKLIQKGL AFVCHQKVEE MRGFEVQLSP WRERPIEENI QLFEDMKNGK 400
    FDEGEATLRL KLTLEEGKVD PVAYRIKYVP HHRTGNQWCI YPTYDYTHCL 450
    CDSIENITHS LCTKEFQSRR SSYYWLCNAL DIYCPVQWEY GRLNVNYTVV 500
    SKRKILKLIT TKTVNDWDDP RLFTLTALRR RGIPSEAINR FVAKLGLTMS 550
    QMVIDPHVLD ATVRDYLNIH APRTMAVLEG LKLTIENFSE LNLPSSVDVP 600
    DFPSDPTDPR KHSVSVDREI FIEKSDYKPD DSDKSFRRLT PKQAVGLKHI 650
    GLVLRFVKEV KDAEGHVTEV VVKAEKLSEK DKPKAFIHWV AKPVSCEVRL 700
    YDRLFKSKNP EDAQLVPGGF LSDINPDSLT VVYNALIDQS IAKSKVYDRF 750
    QFERIGFFCV DRDSTSSTLV FNRTVMLKDG GASGKN 786
    Length:786
    Mass (Da):88,262
    Last modified:August 1, 1998 - v1
    Checksum:iD00F343D845F4B47
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z95559 Genomic DNA. Translation: CAB08998.1.
    PIRiT26811.
    RefSeqiNP_001255843.1. NM_001268914.1.
    UniGeneiCel.7782.

    Genome annotation databases

    EnsemblMetazoaiY41E3.4a; Y41E3.4a; WBGene00001336.
    GeneIDi178415.
    KEGGicel:CELE_Y41E3.4.
    UCSCiY41E3.4. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z95559 Genomic DNA. Translation: CAB08998.1 .
    PIRi T26811.
    RefSeqi NP_001255843.1. NM_001268914.1.
    UniGenei Cel.7782.

    3D structure databases

    ProteinModelPortali O62431.
    SMRi O62431. Positions 2-182, 240-779.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.Y41E3.4.

    Proteomic databases

    PaxDbi O62431.
    PRIDEi O62431.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai Y41E3.4a ; Y41E3.4a ; WBGene00001336 .
    GeneIDi 178415.
    KEGGi cel:CELE_Y41E3.4.
    UCSCi Y41E3.4. c. elegans.

    Organism-specific databases

    CTDi 178415.
    WormBasei Y41E3.4a ; CE18372 ; WBGene00001336 ; qars-1.

    Phylogenomic databases

    eggNOGi COG0008.
    GeneTreei ENSGT00550000074972.
    HOGENOMi HOG000259233.
    InParanoidi O62431.
    KOi K01886.
    OMAi RMQKRAK.
    PhylomeDBi O62431.

    Miscellaneous databases

    NextBioi 901048.
    PROi O62431.

    Family and domain databases

    Gene3Di 1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    InterProi IPR001412. aa-tRNA-synth_I_CS.
    IPR004514. Gln-tRNA-synth.
    IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
    IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR10119. PTHR10119. 1 hit.
    Pfami PF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    PF04558. tRNA_synt_1c_R1. 1 hit.
    PF04557. tRNA_synt_1c_R2. 1 hit.
    [Graphical view ]
    PRINTSi PR00987. TRNASYNTHGLU.
    SUPFAMi SSF50715. SSF50715. 1 hit.
    TIGRFAMsi TIGR00440. glnS. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiSYQ_CAEEL
    AccessioniPrimary (citable) accession number: O62431
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: August 1, 1998
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3