Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O62431

- SYQ_CAEEL

UniProt

O62431 - SYQ_CAEEL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable glutamine--tRNA ligase

Gene

ers-1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei502 – 5021ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamine-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutaminyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamine--tRNA ligase (EC:6.1.1.18)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
Name:ers-1
Synonyms:qrs-5
ORF Names:Y41E3.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiY41E3.4a; CE18372; WBGene00001336; qars-1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 786786Probable glutamine--tRNA ligasePRO_0000195861Add
BLAST

Proteomic databases

PaxDbiO62431.
PRIDEiO62431.

Expressioni

Gene expression databases

ExpressionAtlasiO62431. baseline.

Interactioni

Protein-protein interaction databases

STRINGi6239.Y41E3.4.

Structurei

3D structure databases

ProteinModelPortaliO62431.
SMRiO62431. Positions 2-182, 240-779.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi276 – 28611"HIGH" regionAdd
BLAST
Motifi499 – 5035"KMSKS" region

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
GeneTreeiENSGT00550000074972.
HOGENOMiHOG000259233.
InParanoidiO62431.
KOiK01886.
OMAiRMQKRAK.
PhylomeDBiO62431.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF04558. tRNA_synt_1c_R1. 1 hit.
PF04557. tRNA_synt_1c_R2. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O62431-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATKEELLSL GLSDSKVAET LKNVKLTETI GSIVKLASES GEISKQKGTL
60 70 80 90 100
LYQLATKLKP QVAAHTPLVV KYIMNDGIKT EPQLSAAIEY LLSHTVKGIQ
110 120 130 140 150
VPDFEKSCGV GVVVTIDDIE AAVTKVIGQH REKIVAERYS FPAGKLLGEL
160 170 180 190 200
RALLPWADGA ITKKEVDLRF LELLGPKTAE DLAPKKKEKK PEGPKPSKDA
210 220 230 240 250
AAAATAPGTK NQKEASPEEF ADGAETMDEL LRTRAHFHKV GENFKQDGYV
260 270 280 290 300
TTPKTAELLK AHVAAVGGKV VTRFPPEPNG VLHIGHAKAI NINFGYAKAM
310 320 330 340 350
GGVCNLRFDD TNPEKEEEKF FSAIEDIVHW LGYDPARVTH SSDNFQQLYL
360 370 380 390 400
WAVKLIQKGL AFVCHQKVEE MRGFEVQLSP WRERPIEENI QLFEDMKNGK
410 420 430 440 450
FDEGEATLRL KLTLEEGKVD PVAYRIKYVP HHRTGNQWCI YPTYDYTHCL
460 470 480 490 500
CDSIENITHS LCTKEFQSRR SSYYWLCNAL DIYCPVQWEY GRLNVNYTVV
510 520 530 540 550
SKRKILKLIT TKTVNDWDDP RLFTLTALRR RGIPSEAINR FVAKLGLTMS
560 570 580 590 600
QMVIDPHVLD ATVRDYLNIH APRTMAVLEG LKLTIENFSE LNLPSSVDVP
610 620 630 640 650
DFPSDPTDPR KHSVSVDREI FIEKSDYKPD DSDKSFRRLT PKQAVGLKHI
660 670 680 690 700
GLVLRFVKEV KDAEGHVTEV VVKAEKLSEK DKPKAFIHWV AKPVSCEVRL
710 720 730 740 750
YDRLFKSKNP EDAQLVPGGF LSDINPDSLT VVYNALIDQS IAKSKVYDRF
760 770 780
QFERIGFFCV DRDSTSSTLV FNRTVMLKDG GASGKN
Length:786
Mass (Da):88,262
Last modified:August 1, 1998 - v1
Checksum:iD00F343D845F4B47
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z95559 Genomic DNA. Translation: CAB08998.1.
PIRiT26811.
RefSeqiNP_001255843.1. NM_001268914.1.
UniGeneiCel.7782.

Genome annotation databases

EnsemblMetazoaiY41E3.4a; Y41E3.4a; WBGene00001336.
GeneIDi178415.
KEGGicel:CELE_Y41E3.4.
UCSCiY41E3.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z95559 Genomic DNA. Translation: CAB08998.1 .
PIRi T26811.
RefSeqi NP_001255843.1. NM_001268914.1.
UniGenei Cel.7782.

3D structure databases

ProteinModelPortali O62431.
SMRi O62431. Positions 2-182, 240-779.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.Y41E3.4.

Proteomic databases

PaxDbi O62431.
PRIDEi O62431.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Y41E3.4a ; Y41E3.4a ; WBGene00001336 .
GeneIDi 178415.
KEGGi cel:CELE_Y41E3.4.
UCSCi Y41E3.4. c. elegans.

Organism-specific databases

CTDi 178415.
WormBasei Y41E3.4a ; CE18372 ; WBGene00001336 ; qars-1.

Phylogenomic databases

eggNOGi COG0008.
GeneTreei ENSGT00550000074972.
HOGENOMi HOG000259233.
InParanoidi O62431.
KOi K01886.
OMAi RMQKRAK.
PhylomeDBi O62431.

Miscellaneous databases

NextBioi 901048.
PROi O62431.

Gene expression databases

ExpressionAtlasi O62431. baseline.

Family and domain databases

Gene3Di 1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2.
IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF04558. tRNA_synt_1c_R1. 1 hit.
PF04557. tRNA_synt_1c_R2. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF50715. SSF50715. 1 hit.
TIGRFAMsi TIGR00440. glnS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiSYQ_CAEEL
AccessioniPrimary (citable) accession number: O62431
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: October 29, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3