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Protein
Submitted name:

EXOnuclease

Gene

exo-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ExonucleaseImported, Hydrolase, Nuclease

Enzyme and pathway databases

ReactomeiR-CEL-5358565. Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha).

Names & Taxonomyi

Protein namesi
Submitted name:
EXOnucleaseImported
Gene namesi
Name:exo-1Imported
ORF Names:CELE_F45G2.3Imported, F45G2.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF45G2.3; CE28728; WBGene00009731; exo-1.

PTM / Processingi

Proteomic databases

PaxDbiO62245.
PRIDEiO62245.

Interactioni

Protein-protein interaction databases

IntActiO62245. 1 interaction.
MINTiMINT-117279.
STRINGi6239.F45G2.3.

Structurei

3D structure databases

ProteinModelPortaliO62245.
SMRiO62245. Positions 2-369.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 9999XPGNInterPro annotationAdd
BLAST
Domaini139 – 21274XPGIInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2518. Eukaryota.
COG0258. LUCA.
GeneTreeiENSGT00510000047676.
HOGENOMiHOG000022038.
InParanoidiO62245.
KOiK10746.
OMAiIHMGEET.
OrthoDBiEOG7RNJZZ.
PhylomeDBiO62245.

Family and domain databases

Gene3Di3.40.50.1010. 1 hit.
InterProiIPR020045. 5-3_exonuclease_C.
IPR032641. Exo1.
IPR008918. HhH2.
IPR029060. PIN_domain-like.
IPR006086. XPG-I_dom.
IPR006084. XPG/Rad2.
IPR006085. XPG_DNA_repair_N.
[Graphical view]
PANTHERiPTHR11081. PTHR11081. 2 hits.
PTHR11081:SF8. PTHR11081:SF8. 2 hits.
PfamiPF00867. XPG_I. 1 hit.
PF00752. XPG_N. 1 hit.
[Graphical view]
PRINTSiPR00853. XPGRADSUPER.
SMARTiSM00279. HhH2. 1 hit.
SM00484. XPGI. 1 hit.
SM00485. XPGN. 1 hit.
[Graphical view]
SUPFAMiSSF47807. SSF47807. 1 hit.
SSF88723. SSF88723. 1 hit.

Sequencei

Sequence statusi: Complete.

O62245-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGISGLLPFV KNACRKGNIL ELRGKSVAID VSCLLHRGLT GCMDKIHMGE
60 70 80 90 100
ETQSYVNYVN KYVKELLGMG CHVVMVFDGR PLPAKKGTNE ERRELREKRK
110 120 130 140 150
EHAEMLLAKG LEREARDTYR LATSISADIV ENTIQYFRSM TNVDIVVAPY
160 170 180 190 200
EADAQLAYLV QEKLVDAVIT EDSDLIVFGC EMIYFKWQSA TGECSVYEKC
210 220 230 240 250
NLKNCFTGEL GGDKFDFVKF RRICILSGCD YLQAGLPGVG LSTAAKFFSM
260 270 280 290 300
TSIKDLRTLL RKVPSYLKNP KLKEHVNDEF IRNFEKAENT FKHQIVFDPR
310 320 330 340 350
ERCQKPLTPY PKEVLMTGVD DLEEVIDLDS PKKTAPSSKS FAYAGTASTQ
360 370 380 390 400
RIAIRLALGN PENKSSIDDQ FLLVQPTPEW SVWGLRYESK GSTLDKISKQ
410 420 430 440 450
KELEATQCGG AFKLDSPSVK RVKVASKTTP NDDEDDIVKQ FMADIEKEKK
460 470 480 490 500
AIKKRKNAPQ VDYNADVLLK KYAEPPPEKR QKILEVIDDD FSEFFQEKVK
510 520 530 540 550
ENTKESVAEE KVENSNEELK PPPILRKAVS TPDSARKTHK FQSPLLNHQN
560 570 580 590 600
SAPPSLPDRK PAQTSKYFSK PTSENGVPKT KNPFRCPAFV KPTQKVEEKI
610 620 630
EKTTILAALE ENSVPMPSSN TTYRFVGFKS AGLRRKSKQ
Length:639
Mass (Da):72,104
Last modified:December 1, 2001 - v2
Checksum:i0DE16242F9482DCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAB07612.2.
PIRiT22235.
RefSeqiNP_499770.1. NM_067369.4.
UniGeneiCel.10468.

Genome annotation databases

EnsemblMetazoaiF45G2.3; F45G2.3; WBGene00009731.
GeneIDi176765.
KEGGicel:CELE_F45G2.3.
UCSCiF45G2.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAB07612.2.
PIRiT22235.
RefSeqiNP_499770.1. NM_067369.4.
UniGeneiCel.10468.

3D structure databases

ProteinModelPortaliO62245.
SMRiO62245. Positions 2-369.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO62245. 1 interaction.
MINTiMINT-117279.
STRINGi6239.F45G2.3.

Proteomic databases

PaxDbiO62245.
PRIDEiO62245.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF45G2.3; F45G2.3; WBGene00009731.
GeneIDi176765.
KEGGicel:CELE_F45G2.3.
UCSCiF45G2.3. c. elegans.

Organism-specific databases

CTDi176765.
WormBaseiF45G2.3; CE28728; WBGene00009731; exo-1.

Phylogenomic databases

eggNOGiKOG2518. Eukaryota.
COG0258. LUCA.
GeneTreeiENSGT00510000047676.
HOGENOMiHOG000022038.
InParanoidiO62245.
KOiK10746.
OMAiIHMGEET.
OrthoDBiEOG7RNJZZ.
PhylomeDBiO62245.

Enzyme and pathway databases

ReactomeiR-CEL-5358565. Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha).

Miscellaneous databases

PROiO62245.

Family and domain databases

Gene3Di3.40.50.1010. 1 hit.
InterProiIPR020045. 5-3_exonuclease_C.
IPR032641. Exo1.
IPR008918. HhH2.
IPR029060. PIN_domain-like.
IPR006086. XPG-I_dom.
IPR006084. XPG/Rad2.
IPR006085. XPG_DNA_repair_N.
[Graphical view]
PANTHERiPTHR11081. PTHR11081. 2 hits.
PTHR11081:SF8. PTHR11081:SF8. 2 hits.
PfamiPF00867. XPG_I. 1 hit.
PF00752. XPG_N. 1 hit.
[Graphical view]
PRINTSiPR00853. XPGRADSUPER.
SMARTiSM00279. HhH2. 1 hit.
SM00484. XPGI. 1 hit.
SM00485. XPGN. 1 hit.
[Graphical view]
SUPFAMiSSF47807. SSF47807. 1 hit.
SSF88723. SSF88723. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO62245_CAEEL
AccessioniPrimary (citable) accession number: O62245
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: December 1, 2001
Last modified: June 8, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.