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Protein
Submitted name:

MYOsin heavy chain structural genes

Gene

myo-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, MyosinSAAS annotation

Keywords - Ligandi

Actin-bindingSAAS annotation, ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
MYOsin heavy chain structural genesImported
Gene namesi
Name:myo-6Imported
ORF Names:CELE_F45G2.2Imported, F45G2.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF45G2.2a; CE28727; WBGene00009730; myo-6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiO62244.
PaxDbiO62244.
PeptideAtlasiO62244.

Expressioni

Gene expression databases

BgeeiWBGene00009730.
ExpressionAtlasiO62244. differential.

Interactioni

Protein-protein interaction databases

STRINGi6239.F45G2.2a.

Structurei

3D structure databases

ProteinModelPortaliO62244.
SMRiO62244.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini85 – 781Myosin motorInterPro annotationAdd BLAST697

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili845 – 921Sequence analysisAdd BLAST77
Coiled coili951 – 978Sequence analysisAdd BLAST28
Coiled coili986 – 1034Sequence analysisAdd BLAST49
Coiled coili1091 – 1146Sequence analysisAdd BLAST56

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0161. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00760000118919.
HOGENOMiHOG000173959.
InParanoidiO62244.
OMAiNEPSVIN.
OrthoDBiEOG091G07UM.
PhylomeDBiO62244.

Family and domain databases

Gene3Di4.10.270.10. 1 hit.
InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR027401. Myosin-like_IQ_dom.
IPR001609. Myosin_head_motor_dom.
IPR004009. Myosin_N.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF02736. Myosin_N. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50096. IQ. 1 hit.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O62244-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANIDYMMDP GWKYLRQAQD EALKEQAARR FDNKTHAWVP DAAEGFVTAA
60 70 80 90 100
VAVQEGDNLT FTMPDGTPKK LTRAEVQEIN PAKFEKTEDM SNLTFLNEAS
110 120 130 140 150
VLHNLRQRYY SMMIYTYSGL FCVFINPYKM LPIYTDSVAS MYVNKRRAEM
160 170 180 190 200
PPHLFAVSDE AFRNMMSDKE NQSMLITGES GAGKTENTKK VIAYFAMIGS
210 220 230 240 250
GNKDQKSESS LENQVVQANP AIEAFGNGAT TRNYNSSRYG KFIRIHFDRK
260 270 280 290 300
GKLVGGDIEH YLLEKSRVIK QAPGERSYHI FYQIMTQKAL RERYGLSDNI
310 320 330 340 350
RDYKFVSQAE ITVPGMNDTE EWQITDGAFN VMGFSEREKD DLYKLCSAIM
360 370 380 390 400
HIGNSTFKQK PRDEQAEVDD MTSPTAACKL FGINTDQFLN ALTRPRIKVG
410 420 430 440 450
MEWVNKGQNV QQVDWAVGAL SKAIYARMFN WLIKRVNKTL QANSDEMVYY
460 470 480 490 500
IGVLDIAGFE IFDRNSFEQL WINFVNEKLQ QFFNHHMFVL EQEEYQREGI
510 520 530 540 550
EWTFIDFGLD LQSCIELIEK PLGIVSMLDE ECIVPKASDM TYVDKLLTQH
560 570 580 590 600
LGKHPNFQKA KPPKGKQAEA HFSIMHYAGT VRYNAEQWLD KNKDPLNDSA
610 620 630 640 650
VAILKTSDKE GVLYQLWEEY QTDVDREESE KRGKAQAKKK GKSASFLTVS
660 670 680 690 700
TMYRESLTSL MTMLHTTHPH FIRCIIPNEK KTSGLIDAPL VLNQLTCNGV
710 720 730 740 750
LEGIRICRKG FPNRMMFADF RFRYAILAAD EASDKDAAKA SKAMLRKLSK
760 770 780 790 800
NNQLNVDTFK VGTTKVFFRA GMLARLEELR DEALSAVILK FQCSLRHYLA
810 820 830 840 850
QLEYKRRLDR EDAYPIIQEN IRAWIKLRSW PWYRLFSRLK PMLKGMKSNA
860 870 880 890 900
EIEALEKKCK ELEENHKREE EARKKYADEL RAKIDQYEET KAAHERDRML
910 920 930 940 950
LDKRNKEIEE LNRNLKAESE SNYENAKKAS ELERLREKEK KEWDEKERRM
960 970 980 990 1000
QMEAENEANQ HKTQTEKLKD QISTLQTDFE KVSAQRKAQE QMNAELVDEV
1010 1020 1030 1040 1050
ASFKQKAERA EEQKKKLVED LDSLDDKLAA EKRANNEHVK HNKKLEGQLK
1060 1070 1080 1090 1100
ATQTQLTLAL KEKHEFDVDC KRRESEIGEL KLKAQGDANL ISKLQAMLRK
1110 1120 1130 1140 1150
CISRIEELEE DLLEERKLRM KAERQFNELR SEYEVLQEQM AEASGQLTAE
1160 1170 1180 1190 1200
AHINKVRAEE VSNLRRDLQK RNLNHEAYIS DLCNMQYATV NNLRNLSQQS
1210 1220 1230
ATLESEALRI LDHRRALSKQ PLPRVYVEDP DSDSD
Length:1,235
Mass (Da):143,118
Last modified:December 1, 2001 - v2
Checksum:i976BA4BD0223A236
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAB07611.2.
PIRiT22234.
RefSeqiNP_001022590.1. NM_001027419.3.
UniGeneiCel.4935.

Genome annotation databases

EnsemblMetazoaiF45G2.2a; F45G2.2a; WBGene00009730.
GeneIDi176764.
KEGGicel:CELE_F45G2.2.
UCSCiF45G2.2a. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CAB07611.2.
PIRiT22234.
RefSeqiNP_001022590.1. NM_001027419.3.
UniGeneiCel.4935.

3D structure databases

ProteinModelPortaliO62244.
SMRiO62244.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F45G2.2a.

Proteomic databases

EPDiO62244.
PaxDbiO62244.
PeptideAtlasiO62244.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF45G2.2a; F45G2.2a; WBGene00009730.
GeneIDi176764.
KEGGicel:CELE_F45G2.2.
UCSCiF45G2.2a. c. elegans.

Organism-specific databases

CTDi176764.
WormBaseiF45G2.2a; CE28727; WBGene00009730; myo-6.

Phylogenomic databases

eggNOGiKOG0161. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00760000118919.
HOGENOMiHOG000173959.
InParanoidiO62244.
OMAiNEPSVIN.
OrthoDBiEOG091G07UM.
PhylomeDBiO62244.

Gene expression databases

BgeeiWBGene00009730.
ExpressionAtlasiO62244. differential.

Family and domain databases

Gene3Di4.10.270.10. 1 hit.
InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR027401. Myosin-like_IQ_dom.
IPR001609. Myosin_head_motor_dom.
IPR004009. Myosin_N.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF02736. Myosin_N. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50096. IQ. 1 hit.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO62244_CAEEL
AccessioniPrimary (citable) accession number: O62244
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 126 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.