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O61820 (EIF3E_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit E

Short name=eIF3e
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6
Gene names
Name:eif-3.E
ORF Names:B0511.10
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03004

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03004.

Sequence similarities

Belongs to the eIF-3 subunit E family.

Contains 1 PCI domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 432432Eukaryotic translation initiation factor 3 subunit E HAMAP-Rule MF_03004
PRO_0000123518

Regions

Domain288 – 394107PCI

Sequences

Sequence LengthMass (Da)Tools
O61820 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 5489E810F201633F

FASTA43250,720
        10         20         30         40         50         60 
MSTFDLTQRM APFLDLHLII PLLEFIEPRG IYDEKSLTEM HRQLLTKTNM IDSVIETYNG 

        70         80         90        100        110        120 
KPIPAAIEAK KKQIIKERDE LKSKVDSVVA ILEIPEVKEM MDNNRERDGN VRILEHLTQN 

       130        140        150        160        170        180 
HNFTVDMVDT LFKYSKFMYE CGNYTVASVC LYYYRNLVNQ ADPNYLNALY GKLASEILLQ 

       190        200        210        220        230        240 
EWEHARDDLL KLRAYIDANP FDTEWELVTQ RAWLMHWALF VYYNYPKGRD EIIEMFLNQQ 

       250        260        270        280        290        300 
PYLNAIQVLA PHLLRYLAVA VVTSKSRQKN SLKDLVKVID IERHSYKDPV TDFLTCLYIK 

       310        320        330        340        350        360 
YDFDEAQEML QKCEEVLSND FFLTAVLGDF RESARLLIFE MFCRIHQCIT IEMLARRLNM 

       370        380        390        400        410        420 
SQEEAERWIV DLIRTYRIEG AKIDSKLGQV VMGVKSVSIH EQVMENTKRL TLRAQQIALQ 

       430 
LEKGRQDKVK AT 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO080219 Genomic DNA. Translation: CCD62105.1.
PIRT33118.
RefSeqNP_492785.1. NM_060384.6.
UniGeneCel.22775.

3D structure databases

ProteinModelPortalO61820.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid38371. 1 interaction.
IntActO61820. 2 interactions.
STRING6239.B0511.10.

Proteomic databases

PaxDbO61820.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaB0511.10; B0511.10; WBGene00001228.
GeneID172959.
KEGGcel:CELE_B0511.10.

Organism-specific databases

CTD172959.
WormBaseB0511.10; CE17349; WBGene00001228; eif-3.E.

Phylogenomic databases

eggNOGNOG324642.
GeneTreeENSGT00390000002661.
HOGENOMHOG000036697.
InParanoidO61820.
KOK03250.
OMADILTGKW.
PhylomeDBO61820.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
HAMAPMF_03004. eIF3e.
InterProIPR016650. eIF3e.
IPR019010. eIF3e_N.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERPTHR10317. PTHR10317. 1 hit.
PfamPF09440. eIF3_N. 1 hit.
PF01399. PCI. 1 hit.
[Graphical view]
PIRSFPIRSF016255. eIF3e_su6. 1 hit.
SMARTSM00088. PINT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio877691.
PROO61820.

Entry information

Entry nameEIF3E_CAEEL
AccessionPrimary (citable) accession number: O61820
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: June 11, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase