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Protein
Submitted name:

Proteasome Regulatory Particle, Non-ATPase-like

Gene

rpn-10

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • spermatogenesis Source: WormBase
  • ubiquitin-dependent protein catabolic process Source: WormBase
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-174113. SCF-beta-TrCP mediated degradation of Emi1.
R-CEL-195253. Degradation of beta-catenin by the destruction complex.
R-CEL-4608870. Asymmetric localization of PCP proteins.
R-CEL-4641258. Degradation of DVL.
R-CEL-5632684. Hedgehog 'on' state.
R-CEL-5668541. TNFR2 non-canonical NF-kB pathway.
R-CEL-69017. CDK-mediated phosphorylation and removal of Cdc6.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Proteasome Regulatory Particle, Non-ATPase-likeImported
Gene namesi
Name:rpn-10Imported
ORF Names:B0205.3Imported, CELE_B0205.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiB0205.3; CE26355; WBGene00004466; rpn-10.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiO61742.
PaxDbiO61742.

Interactioni

Protein-protein interaction databases

IntActiO61742. 22 interactions.
MINTiMINT-210565.
STRINGi6239.B0205.3.2.

Structurei

3D structure databases

ProteinModelPortaliO61742.
SMRiO61742. Positions 1-198.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 113108VWFAInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2884. Eukaryota.
COG5148. LUCA.
GeneTreeiENSGT00530000064050.
HOGENOMiHOG000165630.
InParanoidiO61742.
KOiK03029.
OMAiHRTKKKI.
PhylomeDBiO61742.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR027040. Proteasome_su_Rpn10.
IPR003903. UIM_dom.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10223. PTHR10223. 1 hit.
PfamiPF02809. UIM. 2 hits.
PF13519. VWA_2. 1 hit.
[Graphical view]
SMARTiSM00726. UIM. 2 hits.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
PROSITEiPS50330. UIM. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O61742-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQESTMICV DNSEYMRNGD FQPTRLQSQQ DAVNLVTQCK LRANPENAVG
60 70 80 90 100
ILSMANSVQV LSSLSTEQGR LMMKNHSIEP FGKCNFIAGI KIAHLALKHR
110 120 130 140 150
QNRNHKMRVV LFIGSPLEEI EMNELVKIAK KMKKEKVLCD VIMFGENESD
160 170 180 190 200
GHEKFSTFVD TLNGKEGSGS SLIVVPQGSS LTDALLQSSV CKNEDGQAAF
210 220 230 240 250
GGGGNGMDNA FGMDVENDPD LALALRVSME EERARQAAAA AANGGAADSG
260 270 280 290 300
ADAEVAAAAA AVPLEEMDMG AMTEEQQLEW ALRLSMQENA PAEQPQVQHE
310 320 330 340
QMDVDGAPAV GGDNLDDLMN NPELLQQIVD DLPAANAEKD DDKEKK
Length:346
Mass (Da):37,348
Last modified:October 1, 2001 - v2
Checksum:iADAFB35DE60BDE48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD61298.1.
RefSeqiNP_492809.1. NM_060408.4.
UniGeneiCel.5538.

Genome annotation databases

EnsemblMetazoaiB0205.3.1; B0205.3.1; WBGene00004466.
B0205.3.2; B0205.3.2; WBGene00004466.
GeneIDi172977.
KEGGicel:CELE_B0205.3.
UCSCiB0205.3.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD61298.1.
RefSeqiNP_492809.1. NM_060408.4.
UniGeneiCel.5538.

3D structure databases

ProteinModelPortaliO61742.
SMRiO61742. Positions 1-198.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO61742. 22 interactions.
MINTiMINT-210565.
STRINGi6239.B0205.3.2.

Proteomic databases

EPDiO61742.
PaxDbiO61742.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiB0205.3.1; B0205.3.1; WBGene00004466.
B0205.3.2; B0205.3.2; WBGene00004466.
GeneIDi172977.
KEGGicel:CELE_B0205.3.
UCSCiB0205.3.1. c. elegans.

Organism-specific databases

CTDi172977.
WormBaseiB0205.3; CE26355; WBGene00004466; rpn-10.

Phylogenomic databases

eggNOGiKOG2884. Eukaryota.
COG5148. LUCA.
GeneTreeiENSGT00530000064050.
HOGENOMiHOG000165630.
InParanoidiO61742.
KOiK03029.
OMAiHRTKKKI.
PhylomeDBiO61742.

Enzyme and pathway databases

ReactomeiR-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-174113. SCF-beta-TrCP mediated degradation of Emi1.
R-CEL-195253. Degradation of beta-catenin by the destruction complex.
R-CEL-4608870. Asymmetric localization of PCP proteins.
R-CEL-4641258. Degradation of DVL.
R-CEL-5632684. Hedgehog 'on' state.
R-CEL-5668541. TNFR2 non-canonical NF-kB pathway.
R-CEL-69017. CDK-mediated phosphorylation and removal of Cdc6.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR027040. Proteasome_su_Rpn10.
IPR003903. UIM_dom.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10223. PTHR10223. 1 hit.
PfamiPF02809. UIM. 2 hits.
PF13519. VWA_2. 1 hit.
[Graphical view]
SMARTiSM00726. UIM. 2 hits.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
PROSITEiPS50330. UIM. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO61742_CAEEL
AccessioniPrimary (citable) accession number: O61742
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: October 1, 2001
Last modified: June 8, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.