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Protein
Submitted name:

Dopa decarboxylase isoform 2

Gene

Ddc

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BRENDAi4.1.1.28. 358.

Names & Taxonomyi

Protein namesi
Submitted name:
Dopa decarboxylase isoform 2Imported (EC:4.1.1.26Imported)
Gene namesi
Name:DdcImported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei309N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PaxDbiO61718.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP009091-PB.

Structurei

3D structure databases

ProteinModelPortaliO61718.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0628. Eukaryota.
COG0076. LUCA.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR010977. Aromatic_deC.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
PRINTSiPR00800. YHDCRBOXLASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O61718-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVPCETRTE MQAPEFKDFA KEMVDYISNY LENIRDRRVL PTVQPGYLRP
60 70 80 90 100
LIPDEAPQQP EKWEEVMADV ERVIMPGVTH WHSPKFHAYF PTANSYPAIV
110 120 130 140 150
ADMLSGAIAC IGFTWIASPA CTELEVVMLD WLGKMLDLPK EFLACSGGQG
160 170 180 190 200
GGVIQGTASD LALLGLKAKA MKRVKEEHPD WDDNTIVSKL VGYTSNQSHS
210 220 230 240 250
SVERAGLLGG VKLRGLKADE NLNVRGETLE QAIKEDLDAG LIPFYVVATL
260 270 280 290 300
GTTNTCAFDR LDEIGPVANQ YNVWVHVDAY AGSAFICPEY RYLMKGIETA
310 320 330 340 350
DSFNFNPHKW MLVNFDCSAM WLKEPYWIVN AFNVDPLYLK HDMQGSAPDY
360 370 380 390 400
RHWQIPLGRR FRALKLWFVL RLYGVDNLQA HIRRHCAFAK QFEALCRADD
410 420 430 440 450
RFEIFGEVAM GLACFRLKGT NELSEALLKR INGRGNIHLV PSKVNDVYFL
460 470 480
RMAVCSRFTE PADIDYSWKE VAAAADELLA EQKK
Length:484
Mass (Da):54,669
Last modified:August 1, 1998 - v1
Checksum:iAD8D8E79F7139C74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF063021 Genomic DNA. Translation: AAC16247.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF063021 Genomic DNA. Translation: AAC16247.1.

3D structure databases

ProteinModelPortaliO61718.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7165.AGAP009091-PB.

Proteomic databases

PaxDbiO61718.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0628. Eukaryota.
COG0076. LUCA.

Enzyme and pathway databases

BRENDAi4.1.1.28. 358.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR010977. Aromatic_deC.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
PRINTSiPR00800. YHDCRBOXLASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO61718_ANOGA
AccessioniPrimary (citable) accession number: O61718
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: October 5, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.