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Protein

Integrin beta

Gene
N/A
Organism
Lytechinus variegatus (Green sea urchin) (Variegated urchin)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotationImported

Keywords - Biological processi

Cell adhesionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Integrin betaUniRule annotation
OrganismiLytechinus variegatus (Green sea urchin) (Variegated urchin)Imported
Taxonomic identifieri7654 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaTemnopleuroidaToxopneustidaeLytechinus

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei737 – 75923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 806778Integrin betaSequence analysisPRO_5004159960Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO61677.
SMRiO61677. Positions 730-771.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini42 – 473432INBInterPro annotationAdd
BLAST
Domaini655 – 73682Integrin_B_tailInterPro annotationAdd
BLAST
Domaini760 – 80647Integrin_b_cytInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the integrin beta chain family.UniRule annotation
Contains VWFA domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013032. EGF-like_CS.
IPR013111. EGF_extracell.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_N.
IPR012896. Integrin_bsu_tail.
IPR032695. Integrin_dom.
IPR016201. Plexin-like_fold.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PfamiPF07974. EGF_2. 1 hit.
PF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
PF00362. Integrin_beta. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
SM01242. Integrin_B_tail. 1 hit.
SM00423. PSI. 1 hit.
[Graphical view]
SUPFAMiSSF103575. SSF103575. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
SSF69687. SSF69687. 1 hit.
PROSITEiPS00022. EGF_1. 2 hits.
PS00243. INTEGRIN_BETA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O61677-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLHRRQELL LQWIFSVFII SLHVFSDAQS TGTSSSCLQA RTCGDCIITD
60 70 80 90 100
PSCAWCAQPD FQDAENYPRC DSPDTLRERG CMEEHIENPQ STINITQKTP
110 120 130 140 150
LSKAGASVDN LVQVYPQEID LTLRPGEKVS IDLQIRQAED FPVDLYYLMD
160 170 180 190 200
LSDSMSDDLV QLRSLGGILA AEMQNITNNF RLGYGAFIDK TVMPYIDIFP
210 220 230 240 250
AKLQNPCLNK KCGPAFSFHN ILPLTLETGR FTEEVSKVNS SGNLDSPEGG
260 270 280 290 300
MDALMQATVC TEEIGWRDRA RTLLVYTTDA SFHIAGDGKL GGIVKPNDGR
310 320 330 340 350
CHMDDTGFRY TKADEMDYPS ISKLSQKMEA LSILPIFAIG KAGVDKQDPF
360 370 380 390 400
VFYEDLPQYF HESKAARLSA DSSNIVDLIK NVYENITSEV TVGDKADKDL
410 420 430 440 450
FELDYVAHCL DGSVTKDKKT CAGLKLGDQI SFDVSITMKN LSCTVNDGMH
460 470 480 490 500
TISIGPTTFT ENLVLNVKAL CECECSNDVP EPNSSKCSFH GTFTCGACVC
510 520 530 540 550
NEGRSGKICE CDRAEAEGLD ESCVAPNSTV ECSGRGDCVC GLCECDTRGD
560 570 580 590 600
PNRVITGEFC QCDNYLCPRS GGKVCGGSDR GTCECDEDRN INFCTCAEGY
610 620 630 640 650
KGSACXCPIS NDTCRAPNGE ICNGVGTCNC GKCDCNDPKY SGATCQICPD
660 670 680 690 700
CAGACEINQP CVQCRAFHTG AFNKSQCKNC PHPIYVVTEL RKAEGHQECR
710 720 730 740 750
FTDDDECEVI FIYEILPNGT FYIEVQEEKI CPGAPEMLWV ILGIIIGIIL
760 770 780 790 800
VGLALLLIWR LLTYIHDRRE FQNFEKERAN ATWEGGENPI YKPSTSVFKN

PTYNIK
Length:806
Mass (Da):88,832
Last modified:August 1, 1998 - v1
Checksum:i9BC06EAC6BF0587C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF059607 mRNA. Translation: AAC15066.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF059607 mRNA. Translation: AAC15066.1.

3D structure databases

ProteinModelPortaliO61677.
SMRiO61677. Positions 730-771.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013032. EGF-like_CS.
IPR013111. EGF_extracell.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_N.
IPR012896. Integrin_bsu_tail.
IPR032695. Integrin_dom.
IPR016201. Plexin-like_fold.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PfamiPF07974. EGF_2. 1 hit.
PF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
PF00362. Integrin_beta. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
SM01242. Integrin_B_tail. 1 hit.
SM00423. PSI. 1 hit.
[Graphical view]
SUPFAMiSSF103575. SSF103575. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
SSF69687. SSF69687. 1 hit.
PROSITEiPS00022. EGF_1. 2 hits.
PS00243. INTEGRIN_BETA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Lytechinus variegatus beta-C integrin."
    Hertzler P.L., McClay D.R.
    Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO61677_LYTVA
AccessioniPrimary (citable) accession number: O61677
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: June 8, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.